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The first passage time (FPT) for random walks is a key indicator of how fast information diffuses in a given system. Despite the role of FPT as a fundamental feature in transport phenomena, its behavior, particularly in heterogeneous…

Statistical Mechanics · Physics 2015-06-05 S. Hwang , D. -S. Lee , B. Kahng

A physics-informed convolutional neural network is proposed to simulate two phase flow in porous media with time-varying well controls. While most of PICNNs in existing literatures worked on parameter-to-state mapping, our proposed network…

Machine Learning · Computer Science 2024-10-24 Jungang Chen , Eduardo Gildin , John E. Killough

Network models are used to study interconnected systems across many physical, biological, and social disciplines. Such models often assume a particular network-generating mechanism, which when fit to data produces estimates of…

Social and Information Networks · Computer Science 2022-01-17 Ryan E. Langendorf , Matthew G. Burgess

Neural Processes (NPs) are appealing due to their ability to perform fast adaptation based on a context set. This set is encoded by a latent variable, which is often assumed to follow a simple distribution. However, in real-word settings,…

Machine Learning · Computer Science 2023-06-28 Dharmesh Tailor , Mohammad Emtiyaz Khan , Eric Nalisnick

Species sampling processes have long served as the fundamental framework for modeling random discrete distributions and exchangeable sequences. However, data arising from distinct but related sources require a broader notion of…

Statistics Theory · Mathematics 2026-02-03 Beatrice Franzolini , Antonio Lijoi , Igor Prünster , Giovanni Rebaudo

Modelling gene regulatory networks not only requires a thorough understanding of the biological system depicted but also the ability to accurately represent this system from a mathematical perspective. Throughout this chapter, we aim to…

Quantitative Methods · Quantitative Biology 2018-05-04 Olivia Angelin-Bonnet , Patrick J. Biggs , Matthieu Vignes

Phylogenetic mixture models, in which the sites in sequences undergo different substitution processes along the same or different trees, allow the description of heterogeneous evolutionary processes. As data sets consisting of longer…

Populations and Evolution · Quantitative Biology 2012-07-17 Elizabeth S. Allman , John A. Rhodes , Seth Sullivant

We consider a bivariate first hitting-time model in which durations are the crossing times of dependent compound Poisson processes with fixed thresholds. The identifiability of the model is discussed, and likelihood estimators of the model…

Methodology · Statistics 2025-04-14 Mikael Escobar-Bach , Alexandre Popier , Malo Sahin

Collective cell migration plays a crucial role in numerous biological processes, including tumour growth, wound healing, and the immune response. Often, the migrating population consists of cells with various different phenotypes. This…

Populations and Evolution · Quantitative Biology 2025-04-01 Rebecca M. Crossley , Philip K. Maini , Ruth E. Baker

Conventional diffusion models typically relies on a fixed forward process, which implicitly defines complex marginal distributions over latent variables. This can often complicate the reverse process' task in learning generative…

Machine Learning · Statistics 2025-06-10 Grigory Bartosh , Dmitry Vetrov , Christian A. Naesseth

Real-world complex systems such as ecological communities and neuron networks are essential parts of our everyday lives. These systems are composed of units which interact through intricate networks. The ability to predict sudden changes in…

Adaptation and Self-Organizing Systems · Physics 2019-07-05 Deniz Eroglu , Matteo Tanzi , Sebastian van Strien , Tiago Pereira

We present general methods to exactly calculate mean-first passage quantities on self-similar networks defined recursively. In particular, we calculate the mean first-passage time and the splitting probabilities associated to a source and…

Statistical Mechanics · Physics 2015-06-04 B. Meyer , E. Agliari , O. Bénichou , R. Voituriez

Fluctuations in stochastic systems are usually characterized by the full counting statistics, which analyzes the distribution of the number of events taking place in the fixed time interval. In an alternative approach, the distribution of…

Statistical Mechanics · Physics 2018-01-24 Krzysztof Ptaszynski

A class of spiking neuronal models with threshold 2 is considered. It is defined by a set of conditions typical for basic threshold-type models, such as the leaky integrate-and-fire (LIF) or the binding neuron model and also for some…

Neurons and Cognition · Quantitative Biology 2019-08-20 Olha Shchur , Alexander Vidybida

In this paper the problems of the retrospective analysis of models with time-varying structure are considered. These models include contamination models with randomly switching parameters and multivariate classification models with an…

Statistics Theory · Mathematics 2017-10-31 Boris Brodsky , Boris Darkhovsky

Reaction-diffusion processes are the foundational model for a diverse range of complex systems, ranging from biochemical reactions to social agent-based phenomena. The underlying dynamics of these systems occur at the individual…

Statistical Mechanics · Physics 2025-10-15 Mauricio J. del Razo , Margarita Kostré

We propose a model of an adaptive network of spiking neurons that gives rise to a hypernetwork of its dynamic states at the upper level of description. Left to itself, the network exhibits a sequence of transient clustering which relates to…

Adaptation and Self-Organizing Systems · Physics 2017-05-16 Oleg V. Maslennikov , Dmitry S. Shchapin , Vladimir I. Nekorkin

Since its introduction in 1952, Turing's (pre-)pattern theory ("the chemical basis of morphogenesis") has been widely applied to a number of areas in developmental biology. The related pattern formation models normally comprise a system of…

Cell Behavior · Quantitative Biology 2020-10-28 Fiona R Macfarlane , Mark AJ Chaplain , Tommaso Lorenzi

Temporal point processes are the dominant paradigm for modeling sequences of events happening at irregular intervals. The standard way of learning in such models is by estimating the conditional intensity function. However, parameterizing…

Machine Learning · Computer Science 2020-01-24 Oleksandr Shchur , Marin Biloš , Stephan Günnemann

First-passage processes are pervasive across numerous scientific fields, yet a general framework for understanding their response to external perturbations remains elusive. While the fluctuation-dissipation theorem offers a complete linear…

Statistical Mechanics · Physics 2025-08-05 Tommer D. Keidar , Shlomi Reuveni