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Recent experimental and theoretical approaches have attempted to quantify the physical organization (compaction and geometry) of the bacterial chromosome with its complement of proteins (the nucleoid). The genomic DNA exists in a complex…

There are many proteins or protein complexes which have multiple DNA binding domains. This allows them to bind to multiple points on a DNA molecule (or chromatin fibre) at the same time. There are also many proteins which have been found to…

Soft Condensed Matter · Physics 2020-06-24 C. A. Brackley

Nanotechnology has revolutionized the fabrication of hybrid species with tailored functionalities. A milestone in this field is the DNA conjugation of nanoparticles, introduced almost 30 years ago, which typically exploits the affinity…

DNA-coated colloids can crystallize into a multitude of lattices, ranging from face-centered cubic to diamond and thereby contribute to our understanding of crystallization and open avenues to producing structures with useful photonic…

Soft Condensed Matter · Physics 2026-04-17 Pepijn G. Moerman , Huang Fang , Thomas E. Videbæk , W. Benjamin Rogers , Rebecca Schulman

Block copolymer melts offer a unique template to control the position and alignment of nanoparticles due to their ability to self-assemble into periodic ordered structures. Active Brownian particles are shown to co-assemble with block…

Soft Condensed Matter · Physics 2024-03-14 Javier Diaz , Ignacio Pagonabarraga

DNA adsorption on solid or liquid surfaces is a topic of broad fundamental and applied interest. Here we study by x-ray reflectivity the adsorption of monodisperse double-stranded DNA molecules a positively-charged surface, obtained through…

Soft Condensed Matter · Physics 2008-09-29 Carine Douarche , Robert Cortès , Steven J. Roser , Jean-Louis Sikorav , Alan Braslau

Proteins often regulate their activities via allostery - or action at a distance - in which the binding of a ligand at one binding site influences the affinity for another ligand at a distal site. Although less studied than in proteins,…

Statistical Mechanics · Physics 2024-01-11 Midas Segers , Aderik Voorspoels , Takahiro Sakaue , Enrico Carlon

Complex nonequilibrium self-assembly enables the formation of materials with specific patterns and functions from the bottom up. How to directionally control the assembly to form the target configuration is a challenge. Here, we propose a…

Soft Condensed Matter · Physics 2026-01-29 Chaoqun Du , Zhiyu Cao , Zhonghuai Hou

We study the self-assembly of branching-chain networks and crystals in a binary colloidal system with tunable interactions. The particle positions are extracted from microscope images and order parameters are extracted by image processing…

Soft Condensed Matter · Physics 2022-07-19 Hauke Carstensen , Anne Krämer , Vassilios Kapaklis , Max Wolff

In a system of colloidal inclusions suspended in a thermalized bath of smaller particles, the bath engenders an attractive force between the inclusions, arising mainly from entropic origins, known as the depletion force. In the case of…

Soft Condensed Matter · Physics 2020-10-01 Mahdi Zarif , Ali Naji

Electrostatics plays a key role in biomolecular assembly. Oppositely charged biomolecules, for instance, can co-assembled into functional units, such as DNA and histone proteins into nucleosomes and actin-binding protein complexes into…

Materials Science · Physics 2009-11-11 Y. S. Velichko , M. Olvera de la Cruz

The pair interaction between two stiff parallel linear DNA molecules depends not only on the distance between their axes but on their azimuthal orientation. The positional and orientational order in columnar B-DNA assemblies in solution is…

Soft Condensed Matter · Physics 2009-11-07 H. M. Harreis , A. A. Kornyshev , C. N. Likos , H. Loewen , G. Sutmann

We investigate the phase behavior and kinetics of a monodisperse mixture of active (\textit{i.e.}, self-propelled) and passive isometric Brownian particles through Brownian dynamics simulations and theory. As in a purely active system,…

Soft Condensed Matter · Physics 2015-01-08 Joakim Stenhammar , Raphael Wittkowski , Davide Marenduzzo , Michael E. Cates

Interparticle interactions and bulk properties of colloidal suspensions can be substantially modified by addition of nanoparticles. Extreme asymmetries in size and charge between colloidal particles and nanoparticles present severe…

Soft Condensed Matter · Physics 2018-01-03 Alan R. Denton

Inorganic nanocrystal gels retain distinct properties of individual nanocrystals while offering tunable, network structure-dependent characteristics. We review different mechanisms for assembling gels from colloidal nanocrystals including…

DNA nanotechnology promises to provide controllable self-assembly on the nanoscale, allowing for the design of static structures, dynamic machines and computational architectures. In this article I review the state-of-the art of DNA…

Soft Condensed Matter · Physics 2015-07-13 Thomas E. Ouldridge

The use of colloidal supported lipid bilayers (CSLBs) has recently been extended to create colloidal joints, that - in analogy to their macroscopic counterparts - can flexibly connect colloidal particles. These novel elements enable the…

Soft Condensed Matter · Physics 2018-12-20 Melissa Rinaldin , Ruben W. Verweij , Indrani Chakraborty , Daniela J. Kraft

Scaffold proteins organize cellular processes by bringing signaling molecules into interaction, sometimes by forming large signalosomes. Several of these scaffolds are known to polymerize. Their assemblies should therefore not be understood…

Quantitative Methods · Quantitative Biology 2020-03-06 Andrés Ortiz-Muñoz , Héctor F. Medina-Abarca , Walter Fontana

Motile living organisms routinely probe their surroundings to adapt in ever-evolving environments. Although synthetic microswimmers offer surrogates for self-propelled living entities, they often lack the complex feedback mechanisms that…

Electrochemical Biosensors are uniquely positioned to offer real-time in vivo molecular sensing due to their robustness to both biofluids and contaminants found in biofluids, and their adaptability for the detection of different analytes by…

Biological Physics · Physics 2024-10-04 Philip S Lukeman
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