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We propose a fully unsupervised multi-modal deformable image registration method (UMDIR), which does not require any ground truth deformation fields or any aligned multi-modal image pairs during training. Multi-modal registration is a key…

Computer Vision and Pattern Recognition · Computer Science 2019-03-25 Chen Qin , Bibo Shi , Rui Liao , Tommaso Mansi , Daniel Rueckert , Ali Kamen

Blind image deblurring is an important yet very challenging problem in low-level vision. Traditional optimization based methods generally formulate this task as a maximum-a-posteriori estimation or variational inference problem, whose…

Image and Video Processing · Electrical Eng. & Systems 2021-06-08 Hui Wang , Zongsheng Yue , Qian Zhao , Deyu Meng

An unsupervised framework for hyperspectral image (HSI) clustering is proposed that incorporates masked deep representation learning with diffusion-based clustering, extending the Spatially-Regularized Superpixel-based Diffusion Learning…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Vutichart Buranasiri , James M. Murphy

This paper introduces Quicksilver, a fast deformable image registration method. Quicksilver registration for image-pairs works by patch-wise prediction of a deformation model based directly on image appearance. A deep encoder-decoder…

Computer Vision and Pattern Recognition · Computer Science 2017-07-21 Xiao Yang , Roland Kwitt , Martin Styner , Marc Niethammer

The recent application of deep learning in various areas of medical image analysis has brought excellent performance gains. In particular, technologies based on deep learning in medical image registration can outperform traditional…

Image and Video Processing · Electrical Eng. & Systems 2019-09-09 Abdullah Nazib , Clinton Fookes , Dimitri Perrin

We present a novel approach for training deep neural networks in a Bayesian way. Classical, i.e. non-Bayesian, deep learning has two major drawbacks both originating from the fact that network parameters are considered to be deterministic.…

Machine Learning · Statistics 2019-03-11 Konstantin Posch , Jan Steinbrener , Jürgen Pilz

Recently, deep-learning-based approaches have been widely studied for deformable image registration task. However, most efforts directly map the composite image representation to spatial transformation through the convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Jiashun Chen , Donghuan Lu , Yu Zhang , Dong Wei , Munan Ning , Xinyu Shi , Zhe Xu , Yefeng Zheng

Dynamic MRI enables a range of clinical applications, including cardiac function assessment, organ motion tracking, and radiotherapy guidance. However, fully sampling the dynamic k-space data is often infeasible due to time constraints and…

Image and Video Processing · Electrical Eng. & Systems 2025-03-24 George Yiasemis , Jan-Jakob Sonke , Jonas Teuwen

Deformable image registration is a fundamental task in medical image analysis, aiming to establish a dense and non-linear correspondence between a pair of images. Previous deep-learning studies usually employ supervised neural networks to…

Computer Vision and Pattern Recognition · Computer Science 2018-09-11 Jun Zhang

In latest years, deep learning has gained a leading role in the pansharpening of multiresolution images. Given the lack of ground truth data, most deep learning-based methods carry out supervised training in a reduced-resolution domain.…

Image and Video Processing · Electrical Eng. & Systems 2023-07-28 Matteo Ciotola , Giovanni Poggi , Giuseppe Scarpa

This article presents a general Bayesian learning framework for multi-modal groupwise image registration. The method builds on probabilistic modelling of the image generative process, where the underlying common anatomy and geometric…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Xinzhe Luo , Xin Wang , Linda Shapiro , Chun Yuan , Jianfeng Feng , Xiahai Zhuang

Probabilistic atlas priors have been commonly used to derive adaptive and robust brain MRI segmentation algorithms. Widely-used neuroimage analysis pipelines rely heavily on these techniques, which are often computationally expensive. In…

Computer Vision and Pattern Recognition · Computer Science 2019-07-24 Adrian V. Dalca , Evan Yu , Polina Golland , Bruce Fischl , Mert R. Sabuncu , Juan Eugenio Iglesias

Imaging is a standard example of an inverse problem, where the task of reconstructing a ground truth from a noisy measurement is ill-posed. Recent state-of-the-art approaches for imaging use deep learning, spearheaded by unrolled and…

Classical deformable registration techniques achieve impressive results and offer a rigorous theoretical treatment, but are computationally intensive since they solve an optimization problem for each image pair. Recently, learning-based…

Computer Vision and Pattern Recognition · Computer Science 2019-07-26 Adrian V. Dalca , Guha Balakrishnan , John Guttag , Mert R. Sabuncu

Deformable medical image registration plays an important role in clinical diagnosis and treatment. Recently, the deep learning (DL) based image registration methods have been widely investigated and showed excellent performance in…

Image and Video Processing · Electrical Eng. & Systems 2022-10-18 Yibo Wang , Wen Qian , Xuming Zhang

Deep learning methods for unsupervised registration often rely on objectives that assume a uniform noise level across the spatial domain (e.g. mean-squared error loss), but noise distributions are often heteroscedastic and input-dependent…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Xiaoran Zhang , Daniel H. Pak , Shawn S. Ahn , Xiaoxiao Li , Chenyu You , Lawrence H. Staib , Albert J. Sinusas , Alex Wong , James S. Duncan

Deformable image registration is a critical technology in medical image analysis, with broad applications in clinical practice such as disease diagnosis, multi-modal fusion, and surgical navigation. Traditional methods often rely on…

Image and Video Processing · Electrical Eng. & Systems 2026-03-04 Zhengyong Huang , Xingwen Sun , Xuting Chang , Ning Jiang , Yao Wang , Jianfei Sun , Hongbin Han , Yao Sui

Image registration is the process of bringing different images into a common coordinate system - a technique widely used in various applications of computer vision, such as remote sensing, image retrieval, and, most commonly, medical…

Registration is a fundamental task in medical robotics and is often a crucial step for many downstream tasks such as motion analysis, intra-operative tracking and image segmentation. Popular registration methods such as ANTs and NiftyReg…

Computer Vision and Pattern Recognition · Computer Science 2021-03-26 Wentao Zhu , Yufang Huang , Daguang Xu , Zhen Qian , Wei Fan , Xiaohui Xie

Recent advances in deep learning-based medical image registration have shown that training deep neural networks~(DNNs) does not necessarily require medical images. Previous work showed that DNNs trained on randomly generated images with…

Computer Vision and Pattern Recognition · Computer Science 2025-06-02 Junyu Chen , Shuwen Wei , Yihao Liu , Aaron Carass , Yong Du