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Related papers: Multistability of Small Reaction Networks

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Chemical reaction network theory provides powerful tools for rigorously understanding chemical reactions and the dynamical systems and differential equations that represent them. A frequent issue with mathematical analyses of these networks…

Quantitative Methods · Quantitative Biology 2025-12-23 Joseph M. Sauder , Bruce P. Ayati , Ryan Kinser

Microreversibility rules the fluctuations of the currents flowing across open systems in nonequilibrium (or equilibrium) steady states. As a consequence, the statistical cumulants of the currents and their response coefficients at arbitrary…

Statistical Mechanics · Physics 2018-08-15 Maximilien Barbier , Pierre Gaspard

We study networks of biochemical reactions modelled by continuous-time Markov processes. Such networks typically contain many molecular species and reactions and are hard to study analytically as well as by simulation. Particularly, we are…

Molecular Networks · Quantitative Biology 2018-05-22 Daniele Cappelletti , Carsten Wiuf

The singularities of network flow are modeled by self-similarly shrinking solutions called regular shrinkers. In this paper, we study the stability of regular shrinkers. We show that all regular shrinkers with two or more enclosed regions…

Differential Geometry · Mathematics 2021-07-12 Jui-En Chang

We investigate the following generalisation of permutation networks. We say a sequence $T=(T_1,\dots,T_\ell)$ of transpositions in $S_n$ forms a $t$-reachability network if, for every choice of $t$ distinct points $x_1, \dots, x_t\in…

Combinatorics · Mathematics 2025-11-05 Carla Groenland , Tom Johnston , Jamie Radcliffe , Alex Scott

In this paper we study the local instability to the boundary equilibria and the local stability to the positive equilibria for some chemical reaction-diffusion systems. We first analyze a three-species system with boundary equilibria in…

Analysis of PDEs · Mathematics 2020-03-12 Jiaxin Jin

Chemical reaction networks describe interactions between biochemical species. Once an underlying reaction network is given for a biochemical system, the system dynamics can be modelled with various mathematical frameworks such as continuous…

Probability · Mathematics 2023-06-22 German Enciso , Radek Erban , Jinsu Kim

Very often, models in biology, chemistry, physics, and engineering are systems of polynomial or power-law ordinary differential equations, arising from a reaction network. Such dynamical systems can be generated by many different reaction…

Dynamical Systems · Mathematics 2020-01-01 Gheorghe Craciun , Jiaxin Jin , Polly Y. Yu

Networks constructed out of resistors, inductors, capacitors and transformers form a compelling subclass of simple models. Models constructed out of these basic elements are frequently used to explain phenomena in large-scale applications,…

Optimization and Control · Mathematics 2024-10-28 Richard Pates

In the study of grain-surface chemistry in the interstellar medium, there exists much uncertainty regarding the reaction mechanisms with few constraints on the abundances of grain-surface molecules. Bayesian inference can be performed to…

Astrophysics of Galaxies · Physics 2020-12-07 Johannes Heyl , Serena Viti , Jonathan Holdship , Stephen M. Feeney

We study how the properties of allowing multiple positive nondegenerate equilibria (MPNE) and multiple positive linearly stable equilibria (MPSE) are inherited in chemical reaction networks (CRNs). Specifically, when is it that we can…

Dynamical Systems · Mathematics 2017-09-11 Murad Banaji , Casian Pantea

The quasi-steady state approximation and time-scale separation are commonly applied methods to simplify models of biochemical reaction networks based on ordinary differential equations (ODEs). The concentrations of the "fast" species are…

Dynamical Systems · Mathematics 2016-05-10 Meritxell Sáez , Carsten Wiuf , Elisenda Feliu

In this paper we introduce a new representation for the multistationarity region of a reaction network, using polynomial superlevel sets. The advantages of using this polynomial superlevel set representation over the already existing…

Molecular Networks · Quantitative Biology 2022-09-29 AmirHosein Sadeghimanesh , Matthew England

We present a systematic mathematical analysis of the qualitative steady-state response to rate perturbations in large classes of reaction networks. This includes multimolecular reactions and allows for catalysis, enzymatic reactions,…

Dynamical Systems · Mathematics 2017-11-22 Bernhard Brehm , Bernold Fiedler

Small-world networks provide an interesting framework for studying the interplay between regular and random graphs, where links are located in a regular and random way, respectively. On one hand, the random links make the model to obey some…

Statistical Mechanics · Physics 2024-04-12 M. Ostilli

A major challenge in network science is to determine parameters governing complex network dynamics from experimental observations and theoretical models. In complex chemical reaction networks, for example, such as those describing processes…

Disordered Systems and Neural Networks · Physics 2021-06-02 Zachary G. Nicolaou , Adilson E. Motter

A theory of relative species abundance on sparsely-connected networks is presented by investigating the replicator dynamics with symmetric interactions. Sparseness of a network involves difficulty in analyzing the fixed points of the…

Statistical Mechanics · Physics 2016-12-21 Tomoyuki Obuchi , Yoshiyuki Kabashima , Kei Tokita

Drastic change in dynamics and statistics in a chemical reaction system, induced by smallness in the molecule number, is reported. Through stochastic simulations for random catalytic reaction networks, transition to a novel state is…

Adaptation and Self-Organizing Systems · Physics 2009-11-13 Akinori Awazu , Kunihiko Kaneko

Simple nonlinear dynamical systems with multiple stable stationary states are often taken as models for switchlike biological systems. This paper considers the interaction of multiple such simple multistable systems when they are embedded…

Quantitative Methods · Quantitative Biology 2008-04-10 Dennis Cates Wylie

We establish that mass conserving single terminal-linkage networks of chemical reactions admit positive steady states regardless of network deficiency and the choice of reaction rate constants. This result holds for closed systems without…

Molecular Networks · Quantitative Biology 2015-03-19 Santiago Akle , Onkar Dalal , Ronan M. T. Fleming , Michael Saunders , Nicole Taheri , Yinyu Ye