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Despite of decades of work, query optimizers still make mistakes on "difficult" queries because of bad cardinality estimates, often due to the interaction of multiple predicates and correlations in the data. In this paper, we propose a…

Databases · Computer Science 2016-01-22 Wentao Wu , Jeffrey F. Naughton , Harneet Singh

Advancements in computational power and methodologies have enabled research on massive datasets. However, tools for analyzing data with directional or periodic characteristics, such as wind directions and customers' arrival time in 24-hour…

Methodology · Statistics 2026-04-07 Xiang Ye , Janet Van Niekerk , Håvard Rue

Medical events of interest, such as mortality, often happen at a low rate in electronic medical records, as most admitted patients survive. Training models with this imbalance rate (class density discrepancy) may lead to suboptimal…

Machine Learning · Computer Science 2022-08-02 Zepeng Huo , Xiaoning Qian , Shuai Huang , Zhangyang Wang , Bobak J. Mortazavi

Diagnostic accuracy studies assess sensitivity and specificity of a new index test in relation to an established comparator or the reference standard. The development and selection of the index test is usually assumed to be conducted prior…

Methodology · Statistics 2022-08-30 Max Westphal , Antonia Zapf

Principal stratification is a framework for making sense of causal effects conditioned on variables that may themselves have been affected by the treatment. For instance, in an evaluation of an educational intervention, some subjects in the…

Methodology · Statistics 2026-05-05 Adam C. Sales , Kirk P. Vanacore , Erin R. Ottmar

We study a fully funded, collective defined-contribution (DC) pension system with multiple overlapping generations. We investigate whether the welfare of participants can be improved by intergenerational risk sharing (IRS) implemented with…

General Economics · Economics 2023-03-24 An Chen , Motonobu Kanagawa , Fangyuan Zhang

In medical reporting, the accuracy of radiological reports, whether generated by humans or machine learning algorithms, is critical. We tackle a new task in this paper: image-conditioned autocorrection of inaccuracies within these reports.…

Computer Vision and Pattern Recognition · Computer Science 2024-12-05 Arnold Caleb Asiimwe , Dídac Surís , Pranav Rajpurkar , Carl Vondrick

The broad adoption of Electronic Health Records (EHR) has led to vast amounts of data being accumulated on a patient's history, diagnosis, prescriptions, and lab tests. Advances in recommender technologies have the potential to utilize this…

Information Retrieval · Computer Science 2020-09-01 Suman Bhoi , Lee Mong Li , Wynne Hsu

In countries that enabled patients to choose their own providers, a common problem is that the patients did not make rational decisions, and hence, fail to use healthcare resources efficiently. This might cause problems such as overwhelming…

Computers and Society · Computer Science 2020-06-25 Lichin Chen , Yu Tsao , Ji-Tian Sheu

Patients who are seriously ill may ask doctors to treat them with unapproved medication, about which not much is known, or else with known medication in a high dosage. Apart from strict legal constraints such cases may involve difficult…

Other Statistics · Statistics 2018-04-13 F. Thomas Bruss

Problem definition: Personalized medicine (PM) seeks the best treatment for each patient among a set of available treatment methods. Since a specific treatment does not work well on all patients, traditionally, the best treatment was…

Optimization and Control · Mathematics 2023-08-03 Jianzhong Du , Siyang Gao , Chun-Hung Chen

The present state of the art in analytics requires high upfront investment of human effort and computational resources to curate datasets, even before the first query is posed. So-called pay-as-you-go data curation techniques allow these…

Databases · Computer Science 2016-01-05 Arindam Nandi , Ying Yang , Oliver Kennedy , Boris Glavic , Ronny Fehling , Zhen Hua Liu , Dieter Gawlick

There is a mounting crisis in delivering affordable healthcare in the US. For decades, key decision makers in the public and private sectors have considered cost-effectiveness in healthcare a top priority. Their actions have focused on…

Over the years, several studies have demonstrated that there exist significant disparities in health indicators in the United States population across various groups. Healthcare expense is used as a proxy for health in algorithms that drive…

Machine Learning · Computer Science 2019-11-06 Moninder Singh , Karthikeyan Natesan Ramamurthy

The iterative scaling procedure (ISP) is an algorithm which computes a sequence of matrices, starting from some given matrix. The objective is to find a matrix 'proportional' to the given matrix, having given row and column sums. In many…

Statistics Theory · Mathematics 2012-07-24 Erik Aas

Indirect treatment comparisons (ITCs) are essential in Health Technology Assessment (HTA) when head-to-head clinical trials are absent. A common challenge arises when attempting to compare a treatment with available individual patient data…

Computation · Statistics 2026-01-16 Nathan Green

There has been growing interest in developing optimal individualized treatment rules (ITRs) in various fields, such as precision medicine, business decision-making, and social welfare distribution. The application of ITRs within a societal…

Methodology · Statistics 2025-04-29 Wenhai Cui , Wen Su , Xiaodong Yan , Donglin Zeng , Xingqiu Zhao

Automated medical image segmentation inherently involves a certain degree of uncertainty. One key factor contributing to this uncertainty is the ambiguity that can arise in determining the boundaries of a target region of interest,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-28 Qingqiao Hu , Hao Wang , Jing Luo , Yunhao Luo , Zhiheng Zhangg , Jan S. Kirschke , Benedikt Wiestler , Bjoern Menze , Jianguo Zhang , Hongwei Bran Li

Referral workflow inefficiencies, including misaligned referrals and delays, contribute to suboptimal patient outcomes and higher healthcare costs. In this study, we investigated the possibility of predicting procedural needs based on…

Reliable confidence measures of metrics derived from medical imaging reconstruction pipelines would improve the standard of decision-making in many clinical workflows. Conformal Prediction (CP) provides a robust framework for producing…

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