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This article develops flexible methodology to study the association between scalar outcomes and functional predictors observed over time, at many instances, in longitudinal studies. We propose a parsimonious modeling framework to study…

Applications · Statistics 2018-01-25 Md Nazmul Islam , Ana-Maria Staicu , Eric van Heugten

Rapid changes in blood glucose levels can have severe and immediate health consequences, leading to the need to develop indices for assessing these rapid changes based on continuous glucose monitoring (CGM) data. We proposed a CGM index,…

Quantitative Methods · Quantitative Biology 2025-06-17 Dandan Wang , Xiaoyan Chen , Jingxiang Lin , Teng Zhang , Lianyi Huang , Dongliang Leng , Xiaohua Douglas Zhang , Gang Li

As continuous glucose monitors (CGMs) are used increasingly by diabetic patients, new and intuitive tools are needed to help patients and their physicians use these streams of data to improve blood glucose management. In this paper, we…

Quantitative Methods · Quantitative Biology 2013-05-15 Edward Aboufadel

Comorbid chronic conditions are common among people with type 2 diabetes. We developed an Artificial Intelligence algorithm, based on Reinforcement Learning (RL), for personalized diabetes and multi-morbidity management with strong…

Computers and Society · Computer Science 2020-11-05 Hua Zheng , Ilya O. Ryzhov , Wei Xie , Judy Zhong

One common way to test for diabetes is the Oral Glucose Tolerance Test or OGTT. Most common methods for the analysis of the data on this test are wasteful of much of the information contained therein. We propose to model blood glucose…

Applications · Statistics 2019-05-15 Nicolás Kuschinski , J. Andrés Christen , Adriana Monroy , Silvestre Alavez

Many medical decisions involve the use of dynamic information collected on individual patients toward predicting likely transitions in their future health status. If accurate predictions are developed, then a prognostic mode can identify…

Methodology · Statistics 2018-02-22 Aasthaa Bansal , Patrick J. Heagerty

Background and objective: Diabetes is one of the four leading causes of death worldwide, necessitating daily blood glucose monitoring. While sweat offers a promising non-invasive alternative for glucose monitoring, its application remains…

Quantitative Methods · Quantitative Biology 2024-12-05 Xiaoyu Yin , Elisabetta Peri , Eduard Pelssers , Jaap den Toonder , Lisa Klous , Hein Daanen , Massimo Mischi

In this study, we delve into the intricate relationships between diabetes and a range of health indicators, with a particular focus on the newly added variable of income. Utilizing data from the 2015 Behavioral Risk Factor Surveillance…

Machine Learning · Computer Science 2024-04-23 Fariba Jafari Horestani , M. Mehdi Owrang O

Disease progression varies with age and is influenced by underlying genetic, biochemical, and hormonal etiologies, suggesting the need for tailored monitoring, care, and medication beyond standard clinical guidelines. Specifically, in…

Machine Learning · Computer Science 2026-04-28 Beyza Cinar , Maria Maleshkova

Accurate prediction of cardiovascular disease (CVD) risk is crucial for healthcare institutions. This study addresses the growing prevalence of diabetes and its strong link to heart disease by proposing an efficient CVD risk prediction…

Machine Learning · Computer Science 2025-11-10 Esha Chowdhury

Diabetes mellitus is a complex group of syndromes that have in common a disturbance in the body's use of glucose, resulting in an elevated blood sugar. Once detected, sugar diabetes can be controlled by an appropriate regimen that should…

Medical Physics · Physics 2008-11-03 Raju Poddar , Joseph Thomas Andrews , Pratyoosh Shukla , Pratima Sen

This study introduces a novel approach for early Type 2 Diabetes Mellitus (T2DM) risk prediction using a tabular transformer (TabTrans) architecture to analyze longitudinal patient data. By processing patients` longitudinal health records…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Sulaiman Khan , Md. Rafiul Biswas , Zubair Shah

Hybrid models composing mechanistic ODE-based dynamics with flexible and expressive neural network components have grown rapidly in popularity, especially in scientific domains where such ODE-based modeling offers important interpretability…

Machine Learning · Computer Science 2026-02-02 Bob Junyi Zou , Matthew E. Levine , Dessi P. Zaharieva , Ramesh Johari , Emily B. Fox

Metabolic disorders present a pressing global health challenge, with China carrying the world's largest burden. While continuous glucose monitoring (CGM) has transformed diabetes care, its potential for supporting sub-health populations --…

Human-Computer Interaction · Computer Science 2025-11-04 Dongyijie Primo Pan , Lan Luo , Yike Wang , Pan Hui

Simulation of post-prandial pharmacokinetics, such as muscle protein synthesis (MPS) through mTORC1 and insulin-induced glucose uptake, is often challenging due to the computational intensity of the multi-compartmental approach. In this…

Other Quantitative Biology · Quantitative Biology 2026-05-28 Alberto Calderone

Diabetes has a long asymptomatic period which can often remain undiagnosed for multiple years. In this study, we trained a deep learning model to detect new-onset diabetes using 12-lead ECG and readily available demographic information. To…

Machine Learning · Computer Science 2025-12-01 Hao Zhang , Neil Jethani , Aahlad Puli , Leonid Garber , Lior Jankelson , Yindalon Aphinyanaphongs , Rajesh Ranganath

Chronic diseases such as diabetes pose significant management challenges, particularly due to the risk of complications like hypoglycemia, which require timely detection and intervention. Continuous health monitoring through wearable…

Machine Learning · Computer Science 2026-01-08 Vaibhav Gupta , Florian Grensing , Beyza Cinar , Maria Maleshkova

The prevalence of Diabetes mellitus (DM) in the Middle East is exceptionally high as compared to the rest of the world. In fact, the prevalence of diabetes in the Middle East is 17-20%, which is well above the global average of 8-9%.…

Computer Vision and Pattern Recognition · Computer Science 2021-01-12 Muhammad Usman , Kashif Ahmad , Amir Sohail , Marwa Qaraqe

Diabetes mellitus (DM) is a global health issue of significance that must be diagnosed as early as possible and managed well. This study presents a framework for diabetes prediction using Machine Learning (ML) models, complemented with…

Machine Learning · Computer Science 2025-02-13 Pir Bakhsh Khokhar , Viviana Pentangelo , Fabio Palomba , Carmine Gravino

Managing patients with chronic diseases is a major and growing healthcare challenge in several countries. A chronic condition, such as diabetes, is an illness that lasts a long time and does not go away, and often leads to the patient's…

Machine Learning · Computer Science 2020-03-23 Rafael T. Sousa , Lucas A. Pereira , Anderson S. Soares
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