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I propose to use high brightness electron beam with 1 to 100 MeV energy as tool to combat tumor or cancerous tissues in deep part of body. The method is to directly deliver the electron beam to the tumor site via a small tube that connected…

Medical Physics · Physics 2017-06-29 Wei Gai

In this work, we present a fundamental mathematical model for proton transport, tailored to capture the key physical processes underpinning Proton Beam Therapy (PBT). The model provides a robust and computationally efficient framework for…

Accelerated charged particles offer significant physical advantages over X-rays in radiotherapy. In addition to their superior depth-dose distribution, heavy ions provide notable biological benefits compared to protons. Specifically, at…

Medical Physics · Physics 2025-12-19 Jeannette Jansen , Olga Sokol , Yolanda Prezado , Marco Durante

Particle therapy is a well established clinical treatment of tumors. More than one hundred particle therapy centers are in operation world wide. The advantage of using hadrons like protons or carbon ions as particles for tumor irradiation…

Cone-beam computed tomography (CBCT) typically requires hundreds of X-ray projections, which raises concerns about radiation exposure. While sparse-view reconstruction reduces the exposure by using fewer projections, it struggles to achieve…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Meng-Xun Li , Jin-Gang Yu , Yuan Gao , Cui Huang , Gui-Song Xia

Uncertainties in the proton range in tissue during proton therapy limit the precision in treatment delivery. These uncertainties result in expanded treatment margins, thereby increasing radiation dose to healthy tissue. Real-time range…

Medical Physics · Physics 2018-10-17 Kristian Smeland Ytre-Hauge , Kyrre Skjerdal , John Mattingly , Ilker Meric

Deciphering the conditions under which neutron captures occur in the Universe to synthesize heavy elements is an endeavour pursued since the 1950s, but that has proven elusive up to now due to the experimental difficulty of generating the…

Plasma Physics · Physics 2023-12-15 Vojtěch Horný , Sophia N. Chen , Xavier Davoine , Laurent Gremillet , Julien Fuchs

Proton and carbon ion therapy is an emerging technique used for the treatment of solid cancers. The monitoring of the dose delivered during such treatments is still a matter of research. A possible technique exploits the information…

We investigate the adsorption of the nucleic acid bases, adenine (A), guanine (G), cytosine (C), thymine (T) and uracil (U) on the outer wall of a high curvature semiconducting single-walled boron nitride nanotube (BNNT) by first principles…

Biological Physics · Physics 2014-11-20 Saikat Mukhopadhyay , S. Gowtham , Ralph H. Scheicher , Ravindra Pandey , Shashi P. Karna

Neutron capture cross sections of unstable isotopes are important for neutron-induced nucleosynthesis as well as for technological applications. A combination of a radioactive beam facility, an ion storage ring and a high flux reactor would…

The goal of this research project is to give quantitative information useful for the design of a g-ray detector to investigate neutron capture (n, g) reactions on radioactive nuclei at the Manuel Lujan Jr. Neutron Scattering Center (MLNSC)…

It has been known for about sixty years that proton and heavy ion therapy is a very powerful radiation procedure for treating tumours. It has an innate ability to irradiate tumours with greater doses and spatial selectivity compared with…

Plasma Physics · Physics 2014-05-13 K. W. D. Ledingham , P. R. Bolton , N. Shikazono , C-M. Ma

Antineutrino induced electron capture is a resonant process that can have a larg e cross-section for beams of monochromatic antineutrinos. We calculate the cross-section of this process and investigate an experimental setup where…

High Energy Physics - Phenomenology · Physics 2010-01-06 R. G. C. Oldeman , M. Meloni , B. Saitta

Neutron beam, being electrically neutral and highly penetrating, offers unique advantages for irradiation of biological species such as plants, seeds, and microorganisms. We comprehensively investigate the potential of neutron irradiation…

Accelerator Physics · Physics 2024-08-21 May Sweet , Kenji Mishima , Masahide Harada , Keisuke Kurita , Hiroshi Iikura , Seiji Tasaki , Norio Kikuchi

Radioactive ion beams (RIB) are a key focus of current research in nuclear physics. Already long ago it was proposed that they could have applications in cancer therapy. In fact, while charged particle therapy is potentially the most…

Cancer therapy using protons and heavier ions such as carbon has demonstrated advantages over other radiotherapy treatments. To bring about the next generation of clinical facilities, the requirements are likely to reduce the footprint,…

Accelerator Physics · Physics 2021-05-19 H. X. Q. Norman , A. F. Steinberg , R. B. Appleby , H. L. Owen , E. Benedetto , M. Sapinski , S. L. Sheehy

Intracorporeal needle-based therapeutic ultrasound (NBTU) is a minimally invasive option for intervening in malignant brain tumors, commonly used in thermal ablation procedures. This technique is suitable for both primary and metastatic…

Almost since the time of the discovery of the neutron more than 70 years ago, efforts have been made to understand the effects of neutron radiation on tissue and, eventually, to use neutrons for cancer treatment. In contrast to charged…

Nuclear Experiment · Physics 2010-12-15 S. Pomp

In this paper we present the main ideas and discuss both the feasibility and the conceptual design of a novel hybrid technique and equipment for an experimental cancer therapy based on the simultaneous and/or sequential application of two…

The two dominant radiotherapy methods are either simplified in terms of beam generation and handling, which compromises the energy deposition curve in tissues (photon therapy), or require extensive accelerator facilities and complex beam…

Accelerator Physics · Physics 2023-09-12 Marta Monikowska , Marcin Patecki