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We study the contraction of Hodgkin-Huxley model and its role in the reliability of spike timings. Without input, the model is contractive in the region of physiological interest. With impulsive synaptic inputs, contraction is retained…

Systems and Control · Electrical Eng. & Systems 2026-04-20 Alessandro Cecconi , Michelangelo Bin , Lorenzo Marconi , Rodolphe Sepulchre

We review different aspects of the simulation of spiking neural networks. We start by reviewing the different types of simulation strategies and algorithms that are currently implemented. We next review the precision of those simulation…

Cellular signaling is essential in information processing and decision making. Therefore, a variety of experimental approaches have been developed to study signaling on bulk and single-cell level. Single-cell measurements of signaling…

Quantitative Methods · Quantitative Biology 2019-04-18 Carolin Loos , Jan Hasenauer

We implement the Ising model on a structural connectivity matrix describing the brain at a coarse scale. Tuning the model temperature to its critical value, i.e. at the susceptibility peak, we find a maximal amount of total information…

Neurons and Cognition · Quantitative Biology 2013-09-03 Daniele Marinazzo , Mario Pellicoro , Guorong Wu , Leonardo Angelini , Jesus M Cortes , Sebastiano Stramaglia

Many real-world communication networks often have hybrid nature with both fixed nodes and moving modes, such as the mobile phone networks mainly composed of fixed base stations and mobile phones. In this paper, we discuss the information…

Networking and Internet Architecture · Computer Science 2017-10-11 Rongbin Chen , Wei Cui , Cunlai Pu , Jie Li , Bo Ji , Konstantinos Gakis , Panos M. Pardalos

We present a novel mathematical approach to model noise in dynamical systems. We do so by considering dynamics of a chain of diffusively coupled Nagumo cells affected by noise. We show that the noise in transmembrane current can be…

Dynamical Systems · Mathematics 2011-05-13 A. A. Samoletov , B. N. Vasiev

We theoretically describe how weak signals may be efficiently transmitted throughout more than one frequency range in noisy excitable media by kind of stochastic multiresonance. This serves us here to reinterpret recent experiments in…

Data Analysis, Statistics and Probability · Physics 2015-05-27 J. J. Torres , J. Marro , J. F. Mejias

Model calculations have been performed on the spike-train response of a pair of Hodgkin-Huxley (HH) neurons coupled by recurrent excitatory-excitatory couplings with time delay. The coupled, excitable HH neurons are assumed to receive the…

Disordered Systems and Neural Networks · Physics 2009-10-31 Hideo Hasegawa

The dynamics of a multiplex heterogeneous network of oscillators is studied. Two types of similar models based on the Hodgkin-Huxley formalism are used as the basic elements of the networks. The first type model demonstrates bursting…

Disordered Systems and Neural Networks · Physics 2021-06-03 Nataliya Stankevich

A great variety of systems in nature, society and technology -- from the web of sexual contacts to the Internet, from the nervous system to power grids -- can be modeled as graphs of vertices coupled by edges. The network structure,…

Adaptation and Self-Organizing Systems · Physics 2012-10-10 Petter Holme , Jari Saramäki

In this paper we deal with a feedback control design for the action potential of a neuronal membrane in relation with the non-linear dynamics of the Hodgkin-Huxley mathematical model. More exactly, by using an external current as a control…

Optimization and Control · Mathematics 2020-04-22 Cecilia Cavaterra , Denis Enachescu , Gabriela Marinoschi

In this paper mathematical models are formulated in order to simulate heat production and corresponding temperature changes which accompany the propagation of an axon potential. Based on earlier experimental results, several models are…

Biological Physics · Physics 2019-07-24 Kert Tamm , Jüri Engelbrecht , Tanel Peets

The nervous system represents time-dependent signals in sequences of discrete action potentials or spikes, all spikes are identical so that information is carried only in the spike arrival times. We show how to quantify this information, in…

Condensed Matter · Physics 2008-02-03 S. P. Strong , Roland Koberle , Rob R. de Ruyter van Steveninck , William Bialek

The Hodgkin-Huxley model describes the conduction of the nervous impulse through the axon, whose membrane's electric response can be described employing multiple connected electric circuits containing capacitors, voltage sources, and…

Neurons and Cognition · Quantitative Biology 2021-12-13 Tasio Gonzalez-Raya , Enrique Solano , Mikel Sanz

This work explores four nonlinear classical models of neural oscillators, the Hodgkin-Huxley model, the Fitzhugh-Nagumo model, the Morris-Lecar model, and the Hindmarsh-Rose model. Nonlinear contraction theory is used to develop observers…

Neurons and Cognition · Quantitative Biology 2013-10-03 Ranjeetha Bharath , Jean-Jacques Slotine

Transient phenomena play a key role in coordinating brain activity at multiple scales, however,their underlying mechanisms remain largely unknown. A key challenge for neural data science is thus to characterize the network interactions at…

Neurons and Cognition · Quantitative Biology 2022-09-16 Kaidi Shao , Nikos K. Logothetis , Michel Besserve

Experimental manipulations perturb the neuronal activity. This phenomenon is manifested in the fMRI response. Dynamic causal model and its variants can model these neuronal responses along with the BOLD responses [1, 2, 3, 4, 5] .…

Neurons and Cognition · Quantitative Biology 2021-01-15 Sayan Nag

Synaptic, dendritic and single-cell kinetics generate significant time delays that shape the dynamics of large networks of spiking neurons. Previous work has shown that such effective delays can be taken into account with a rate model…

Neurons and Cognition · Quantitative Biology 2014-01-31 Alex Roxin , Ernest Montbrio

The classical Hodgkin-Huxley (HH) point-neuron model of action potential generation is four-dimensional. It consists of four ordinary differential equations describing the dynamics of the membrane potential and three gating variables…

Neurons and Cognition · Quantitative Biology 2023-02-16 Ulises Chialva , Vicente González Boscá , Horacio G. Rotstein

Human heart rate fluctuates in a complex and non-stationary manner. Elaborating efficient and adequate tools for the analysis of such signals has been a great challenge for the researchers during last decades. Here, an overview of the main…

Medical Physics · Physics 2007-05-23 J. Kalda , M. Sakki , M. Vainu , M. Laan