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Causal discovery algorithms estimate causal graphs from observational data. This can provide a valuable complement to analyses focussing on the causal relation between individual treatment-outcome pairs. Constraint-based causal discovery…

Methodology · Statistics 2021-08-31 Janine Witte , Ronja Foraita , Vanessa Didelez

Graph-based Multiple Instance Learning (MIL) is widely used in survival analysis with Hematoxylin and Eosin (H\&E)-stained whole slide images (WSIs) due to its ability to capture topological information. However, variations in staining and…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Min Cen , Zhenfeng Zhuang , Yuzhe Zhang , Min Zeng , Baptiste Magnier , Lequan Yu , Hong Zhang , Liansheng Wang

Two popular approaches for relating correlated measurements of a non-Gaussian response variable to a set of predictors are to fit a marginal model using generalized estimating equations and to fit a generalized linear mixed model by…

Methodology · Statistics 2017-02-23 Jeffrey J. Gory , Peter F. Craigmile , Steven N. MacEachern

Three distinct phenomena complicate statistical causal analysis: latent common causes, causal cycles, and latent selection. Foundational works on Structural Causal Models (SCMs), e.g., Bongers et al. (2021, Ann. Stat., 49(5): 2885-2915),…

Methodology · Statistics 2025-11-23 Leihao Chen , Onno Zoeter , Joris M. Mooij

While LLM-based agents excel at planning and executing long action sequences, their execution often remains inconsistent across trials, limiting reliability. Consolidating agent consistency requires distilling trial-error trajectories into…

Machine Learning · Computer Science 2026-05-12 Zihan Huang , Junda Wu , Tong Yu , Qianqi Yan , Rohan Surana , Uttaran Bhattacharya , Lina Yao , Xin Eric Wang , Julian McAuley

Causal mediation analysis is widely utilized to separate the causal effect of treatment into its direct effect on the outcome and its indirect effect through an intermediate variable (the mediator). In this study we introduce a functional…

Applications · Statistics 2018-05-21 Yi Zhao , Xi Luo , Martin Lindquist , Brian Caffo

Learning identifiable representations and models from low-level observations is helpful for an intelligent spacecraft to complete downstream tasks reliably. For temporal observations, to ensure that the data generating process is provably…

Machine Learning · Computer Science 2024-12-05 Congxi Zhang , Yongchun Xie

A key challenge for robotic systems is to figure out the behavior of another agent. The capability to draw correct inferences is crucial to derive human behavior from examples. Processing correct inferences is especially challenging when…

Robotics · Computer Science 2022-07-19 Alexander Wich , Holger Schultheis , Michael Beetz

Models and simulations of collective behaviours are often based on considering them as assumed by interactive particle systems. The focus is then on behavioural and interaction rules by using approaches based on artificial agents designed…

Adaptation and Self-Organizing Systems · Physics 2009-03-04 Gianfranco Minati

Decomposing an exposure effect on an outcome into separate natural indirect effects through multiple mediators requires strict assumptions, such as correctly postulating the causal structure of the mediators, and no unmeasured confounding…

Methodology · Statistics 2021-02-04 Wen Wei Loh , Beatrijs Moerkerke , Tom Loeys , Stijn Vansteelandt

Visual language models (VLMs) have demonstrated strong performance across diverse multimodal reasoning tasks but still face challenges such as hallucinations, resulting in incorrect reasoning outcomes. Inspired by recent research on…

Multimedia · Computer Science 2025-04-16 Shuhang Liu , Zhenrong Zhang , Pengfei Hu , Jiefeng Ma , Jun Du , Qing Wang , Jianshu Zhang , Quan Liu , Jianqing Gao , Feng Ma

Multimodal Large Language Models demonstrate strong performance on multimodal benchmarks, yet often exhibit poor robustness when exposed to spurious modality interference, such as irrelevant text in vision understanding, or irrelevant…

Machine Learning · Computer Science 2026-01-30 Rui Cai , Bangzheng Li , Xiaofei Wen , Muhao Chen , Zhe Zhao

Unlike other techniques of causality inference, the use of valid instrumental variables can deal with unobserved sources of both variable errors, variable omissions, and sampling bias, and still arrive at consistent estimates of average…

Econometrics · Economics 2021-02-17 Øyvind Hoveid

Causal discovery with latent variables is a crucial but challenging task. Despite the emergence of numerous methods aimed at addressing this challenge, they are not fully identified to the structure that two observed variables are…

Machine Learning · Computer Science 2023-12-20 Wei Chen , Zhiyi Huang , Ruichu Cai , Zhifeng Hao , Kun Zhang

This paper combines causal mediation analysis with double machine learning to control for observed confounders in a data-driven way under a selection-on-observables assumption in a high-dimensional setting. We consider the average indirect…

Econometrics · Economics 2021-02-17 Helmut Farbmacher , Martin Huber , Lukáš Lafférs , Henrika Langen , Martin Spindler

Causal mediation analysis aims to estimate the natural direct and indirect effects under clearly specified assumptions. Traditional mediation analysis based on Ordinary Least Squares (OLS) relies on the absence of unmeasured causes of the…

Methodology · Statistics 2017-07-07 Cedric E. Ginestet , Richard Emsley , Sabine Landau

Instrumental variable (IV) methods are used to estimate causal effects in settings with unobserved confounding, where we cannot directly experiment on the treatment variable. Instruments are variables which only affect the outcome…

Methodology · Statistics 2023-05-26 Elisabeth Ailer , Jason Hartford , Niki Kilbertus

Studies investigating the causal effects of spatially varying exposures on outcomes often rely on observational and spatially indexed data. A prevalent challenge is unmeasured spatial confounding, where an unobserved spatially varying…

Methodology · Statistics 2025-11-19 Sophie M. Woodward , Mauricio Tec , Francesca Dominici

Discovering causal structures among latent factors from observed data is a particularly challenging problem. Despite some efforts for this problem, existing methods focus on the single-domain data only. In this paper, we propose…

Machine Learning · Computer Science 2022-04-26 Yan Zeng , Shohei Shimizu , Ruichu Cai , Feng Xie , Michio Yamamoto , Zhifeng Hao

In this work, we present sequence-driven structural causal models (SD-SCMs), a framework for specifying causal models with user-defined structure and language-model-defined mechanisms. We characterize how an SD-SCM enables sampling from…

Computation and Language · Computer Science 2025-09-24 Lucius E. J. Bynum , Kyunghyun Cho
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