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Deformable image registration remains a central challenge in medical image analysis, particularly under multi-modal scenarios where intensity distributions vary significantly across scans. While deep learning methods provide efficient…

Image and Video Processing · Electrical Eng. & Systems 2026-03-30 Yi Zhang , Yidong Zhao , Qian Tao

Multi-contrast image registration is a challenging task due to the complex intensity relationships between different imaging contrasts. Conventional image registration methods are typically based on iterative optimizations for each input…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Yinsong Wang , Siyi Du , Shaoming Zheng , Xinzhe Luo , Chen Qin

Deformable medical image registration is an essential task in computer-assisted interventions. This problem is particularly relevant to oncological treatments, where precise image alignment is necessary for tracking tumor growth, assessing…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Stefano Fogarollo , Gregor Laimer , Reto Bale , Matthias Harders

Proton therapy offers superior organ-at-risk sparing but is highly sensitive to anatomical changes, making accurate deformable image registration (DIR) across longitudinal CT scans essential. Conventional DIR methods are often too slow for…

With recent advances in computing hardware and surges of deep-learning architectures, learning-based deep image registration methods have surpassed their traditional counterparts, in terms of metric performance and inference time. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-13 Bin Duan , Ming Zhong , Yan Yan

Image registration techniques usually assume that the images to be registered are of a certain type (e.g. single- vs. multi-modal, 2D vs. 3D, rigid vs. deformable) and there lacks a general method that can work for data under all…

Image and Video Processing · Electrical Eng. & Systems 2025-01-28 Quang Luong Nhat Nguyen , Ruiming Cao , Laura Waller

Reliably and physically accurately transferring information between images through deformable image registration with large anatomical differences is an open challenge in medical image analysis. Most existing methods have two key…

Computer Vision and Pattern Recognition · Computer Science 2023-03-13 Georgios Andreadis , Peter A. N. Bosman , Tanja Alderliesten

Medical image registration is a difficult problem. Not only a registration algorithm needs to capture both large and small scale image deformations, it also has to deal with global and local image intensity variations. In this paper we…

Computer Vision and Pattern Recognition · Computer Science 2009-07-14 Ulas Bagci , Li Bai

Deep learning (DL) has led to significant improvements in medical image synthesis, enabling advanced image-to-image translation to generate synthetic images. However, DL methods face challenges such as domain shift and high demands for…

Image and Video Processing · Electrical Eng. & Systems 2024-02-20 Savannah P. Hays , Lianrui Zuo , Yihao Liu , Anqi Feng , Jiachen Zhuo , Jerry L. Prince , Aaron Carass

Image registration is a fundamental task in medical image analysis. Recently, deep learning based image registration methods have been extensively investigated due to their excellent performance despite the ultra-fast computational time.…

Computer Vision and Pattern Recognition · Computer Science 2020-08-14 Boah Kim , Dong Hwan Kim , Seong Ho Park , Jieun Kim , June-Goo Lee , Jong Chul Ye

3D medical image registration is of great clinical importance. However, supervised learning methods require a large amount of accurately annotated corresponding control points (or morphing), which are very difficult to obtain. Unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2020-05-11 Shengyu Zhao , Tingfung Lau , Ji Luo , Eric I-Chao Chang , Yan Xu

Deformable registration of magnetic resonance images between patients with brain tumors and healthy subjects has been an important tool to specify tumor geometry through location alignment and facilitate pathological analysis. Since tumor…

Image and Video Processing · Electrical Eng. & Systems 2021-01-19 Xiaofeng Liu , Fangxu Xing , Chao Yang , C. -C. Jay Kuo , Georges ElFakhri , Jonghye Woo

Deformable image registration plays a fundamental role in medical image analysis by enabling spatial alignment of anatomical structures across subjects. While recent deep learning-based approaches have significantly improved computational…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jiaqi Shang , Haojin Wu , Yinyi Lai , Zongyu Li , Chenghao Zhang , Jia Guo

Deformable image registration is a critical technology in medical image analysis, with broad applications in clinical practice such as disease diagnosis, multi-modal fusion, and surgical navigation. Traditional methods often rely on…

Image and Video Processing · Electrical Eng. & Systems 2026-03-04 Zhengyong Huang , Xingwen Sun , Xuting Chang , Ning Jiang , Yao Wang , Jianfei Sun , Hongbin Han , Yao Sui

Robust and accurate 2D/3D registration, which aligns preoperative models with intraoperative images of the same anatomy, is crucial for successful interventional navigation. To mitigate the challenge of a limited field of view in…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Yuxin Cui , Rui Song , Yibin Li , Max Q. -H. Meng , Zhe Min

A novel non-rigid image registration algorithm is built upon fully convolutional networks (FCNs) to optimize and learn spatial transformations between pairs of images to be registered in a self-supervised learning framework. Different from…

Computer Vision and Pattern Recognition · Computer Science 2018-01-15 Hongming Li , Yong Fan

We present a diffeomorphic image registration algorithm to learn spatial transformations between pairs of images to be registered using fully convolutional networks (FCNs) under a self-supervised learning setting. The network is trained to…

Computer Vision and Pattern Recognition · Computer Science 2020-10-06 Hongming Li , Yong Fan

Learning non-rigid registration in an end-to-end manner is challenging due to the inherent high degrees of freedom and the lack of labeled training data. In this paper, we resolve these two challenges simultaneously. First, we propose to…

Computer Vision and Pattern Recognition · Computer Science 2021-04-14 Wanquan Feng , Juyong Zhang , Hongrui Cai , Haofei Xu , Junhui Hou , Hujun Bao

Indirect image registration is a promising technique to improve image reconstruction quality by providing a shape prior for the reconstruction task. In this paper, we propose a novel hybrid method that seeks to reconstruct high quality…

Image and Video Processing · Electrical Eng. & Systems 2019-12-18 Jiulong Liu , Angelica I. Aviles-Rivero , Hui Ji , Carola-Bibiane Schönlieb

We propose a novel non-rigid image registration algorithm that is built upon fully convolutional networks (FCNs) to optimize and learn spatial transformations between pairs of images to be registered. Different from most existing deep…

Computer Vision and Pattern Recognition · Computer Science 2017-09-05 Hongming Li , Yong Fan