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Non-invasive colorectal cancer (CRC) screening represents a key opportunity to improve colonoscopy participation rates and reduce CRC mortality. This study explores the potential of the gut-liver axis for predicting colorectal neoplasia…

Colorectal cancer remains a major global health concern, with early detection being pivotal for improving patient outcomes. In this study, we leveraged high throughput methylation profiling of cellfree DNA to identify and validate…

Genomics · Quantitative Biology 2025-05-19 Kartavya Mathur , Shipra Jain , Nisha Bajiya , Nishant Kumar , Gajendra P. S. Raghava

As the global population ages, the incidence of Chronic Kidney Disease (CKD) is rising. CKD often remains asymptomatic until advanced stages, which significantly burdens both the healthcare system and patient quality of life. This research…

Artificial Intelligence · Computer Science 2024-04-18 Nantika Nguycharoen

Endoscopy provides a major contribution to the diagnosis of the Gastrointestinal Tract (GIT) diseases. With Colon Endoscopy having its certain limitations, Wireless Capsule Endoscopy is gradually taking over it in the terms of ease and…

Image and Video Processing · Electrical Eng. & Systems 2020-09-03 Vanshika Vats , Pooja Goel , Amodini Agarwal , Nidhi Goel

Skin cancer is one of the major types of cancers with an increasing incidence over the past decades. Accurately diagnosing skin lesions to discriminate between benign and malignant skin lesions is crucial to ensure appropriate patient…

Computer Vision and Pattern Recognition · Computer Science 2019-04-26 Amirreza Mahbod , Gerald Schaefer , Chunliang Wang , Rupert Ecker , Isabella Ellinger

Collagen, a key structural component of the extracellular matrix, undergoes significant remodeling during carcinogenesis. However, the important role of collagen levels in breast cancer diagnostics still lacks effective in vivo detection…

Optics · Physics 2024-10-14 Jiayan Li , Lu Bai , Yingna Chen , Junmei Cao , Jingtao Zhu , Wanxiang Zhi , Qian Cheng

There has been a substantial amount of research involving computer methods and technology for the detection and recognition of diabetic foot ulcers (DFUs), but there is a lack of systematic comparisons of state-of-the-art deep learning…

The rapid development of deep learning, a family of machine learning techniques, has spurred much interest in its application to medical imaging problems. Here, we develop a deep learning algorithm that can accurately detect breast cancer…

Computer Vision and Pattern Recognition · Computer Science 2019-10-08 Li Shen , Laurie R. Margolies , Joseph H. Rothstein , Eugene Fluder , Russell B. McBride , Weiva Sieh

Colonoscopy is a routine outpatient procedure used to examine the colon and rectum for any abnormalities including polyps, diverticula and narrowing of colon structures. A significant amount of the clinician's time is spent in…

Computer Vision and Pattern Recognition · Computer Science 2022-09-28 Aniruddha Tamhane , Tse'ela Mida , Erez Posner , Moshe Bouhnik

Colorectal cancer liver metastases (CLM) are the most common type of distant metastases originating from the abdomen and are characterized by a high recurrence rate after curative resection. It has been previously reported that CLM…

Quantitative Methods · Quantitative Biology 2023-03-09 Ralph Saber , David Henault , Rolando Rebolledo , Simon Turcotte , Samuel Kadoury

Colorectal cancer is a one of the highest causes of cancer-related death, especially in men. Polyps are one of the main causes of colorectal cancer and early diagnosis of polyps by colonoscopy could result in successful treatment. Diagnosis…

Image and Video Processing · Electrical Eng. & Systems 2018-02-02 Mojtaba Akbari , Majid Mohrekesh , Ebrahim Nasr-Esfahani , S. M. Reza Soroushmehr , Nader Karimi , Shadrokh Samavi , Kayvan Najarian

In this paper, we explore the possibility to apply machine learning to make diagnostic predictions using discomfort drawings. A discomfort drawing is an intuitive way for patients to express discomfort and pain related symptoms. These…

Machine Learning · Computer Science 2016-09-14 Cheng Zhang , Hedvig Kjellstrom , Carl Henrik Ek , Bo C. Bertilson

Segmentation of histopathology sections is an ubiquitous requirement in digital pathology and due to the large variability of biological tissue, machine learning techniques have shown superior performance over standard image processing…

Computer Vision and Pattern Recognition · Computer Science 2017-10-11 Philipp Kainz , Michael Pfeiffer , Martin Urschler

Celiac Disease (CD) is a chronic autoimmune disease that affects the small intestine in genetically predisposed children and adults. Gluten exposure triggers an inflammatory cascade which leads to compromised intestinal barrier function. If…

Image and Video Processing · Electrical Eng. & Systems 2019-10-09 Rasoul Sali , Lubaina Ehsan , Kamran Kowsari , Marium Khan , Christopher A. Moskaluk , Sana Syed , Donald E. Brown

Optical colonoscopy is an essential diagnostic and prognostic tool for many gastrointestinal diseases, including cancer screening and staging, intestinal bleeding, diarrhea, abdominal symptom evaluation, and inflammatory bowel disease…

Computer Vision and Pattern Recognition · Computer Science 2021-12-10 Heming Yao , Ryan W. Stidham , Zijun Gao , Jonathan Gryak , Kayvan Najarian

Colorectal cancer (CRC) is among the top three malignant tumor types in terms of morbidity and mortality. Histopathological images are the gold standard for diagnosing colon cancer. Cellular nuclei instance segmentation and classification,…

Computer Vision and Pattern Recognition · Computer Science 2024-01-29 Liangrui Pan , Lian Wang , Zhichao Feng , Zhujun Xu , Liwen Xu , Shaoliang Peng

Skin cancer is among the most prevalent and life-threatening diseases worldwide, with early detection being critical to patient outcomes. This work presents a hybrid machine and deep learning-based approach for classifying malignant and…

Image and Video Processing · Electrical Eng. & Systems 2025-06-05 Muhammad Zubair Hasan , Fahmida Yasmin Rifat

Existing universal lesion detection (ULD) methods utilize compute-intensive anchor-based architectures which rely on predefined anchor boxes, resulting in unsatisfactory detection performance, especially in small and mid-sized lesions.…

Computer Vision and Pattern Recognition · Computer Science 2022-03-31 Manu Sheoran , Meghal Dani , Monika Sharma , Lovekesh Vig

Skin cancer, the most common human malignancy, is primarily diagnosed visually by physicians [1]. Classification with an automated method like CNN [2, 3] shows potential for challenging tasks [1]. By now, the deep convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2017-03-13 Wenhao Zhang , Liangcai Gao , Runtao Liu

One of the most serious corneal disorders, keratoconus is difficult to diagnose in its early stages and can result in blindness. This illness, which often appears in the second decade of life, affects people of all sexes and races.…

Image and Video Processing · Electrical Eng. & Systems 2023-11-06 AKM Enzam-Ul Haque , Golam Rabbany , Md. Siam