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Celiac disease prevalence and diagnosis have increased substantially in recent years. The current gold standard for celiac disease confirmation is visual examination of duodenal mucosal biopsies. An accurate computer-aided biopsy analysis…

Computer Vision and Pattern Recognition · Computer Science 2019-02-01 Jason W. Wei , Jerry W. Wei , Christopher R. Jackson , Bing Ren , Arief A. Suriawinata , Saeed Hassanpour

Objective: Ulcerative colitis (UC), characterized by chronic inflammation with alternating remission-relapse cycles, requires precise histological healing (HH) evaluation to improve clinical outcomes. To overcome the limitations of…

Quantitative Methods · Quantitative Biology 2025-05-16 Zhengxuan Qiu , Bo Peng , Xiaoying Tang , Jiankun Wang , Qin Guo

Inflammatory bowel diseases (IBD) are complex diseases in which the gut microbiota is attacked by the immune system of genetically predisposed subjects when they are exposed to yet unclear environmental factors. The complexity of this class…

Quantitative Methods · Quantitative Biology 2022-08-17 Mirko Hu , Guido Caldarelli , Tommaso Gili

Inflammatory Bowel Disease (IBD), including Crohn's Disease (CD) and Ulcerative Colitis (UC), presents significant public health challenges due to its complex etiology. Motivated by the IBD study of the Integrative Human Microbiome Project,…

Applications · Statistics 2025-10-28 Limeng Liu , Guannan Wang , Sandra E. Safo

Colorectal cancer is the third most common cancer-related death after lung cancer and breast cancer worldwide. The risk of developing colorectal cancer could be reduced by early diagnosis of polyps during a colonoscopy. Computer-aided…

Image and Video Processing · Electrical Eng. & Systems 2020-04-24 Sara Hosseinzadeh Kassani , Peyman Hosseinzadeh Kassani , Michal J. Wesolowski , Kevin A. Schneider , Ralph Deters

Foot ulcer is a common complication of diabetes mellitus and, associated with substantial morbidity and mortality, remains a major risk factor for lower leg amputations. Extracting accurate morphological features from foot wounds is crucial…

Image and Video Processing · Electrical Eng. & Systems 2022-06-20 Amirreza Mahbod , Gerald Schaefer , Rupert Ecker , Isabella Ellinger

Inflammatory bowel disease (IBD) involves chronic inflammation of the digestive tract, with treatment options often burdened by adverse effects. Identifying biomarkers for personalized treatment is crucial. While immune cells play a key…

Image and Video Processing · Electrical Eng. & Systems 2025-04-15 Ruiwen Ding , Lin Li , Rajath Soans , Tosha Shah , Radha Krishnan , Marc Alexander Sze , Sasha Lukyanov , Yash Deshpande , Antong Chen

Colonoscopy screening effectively identifies and removes polyps before they progress to colorectal cancer (CRC), but current follow-up guidelines rely primarily on histopathological features, overlooking other important CRC risk factors.…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Shuai Jiang , Christina Robinson , Joseph Anderson , William Hisey , Lynn Butterly , Arief Suriawinata , Saeed Hassanpour

Colonic polyps are well-recognized precursors to colorectal cancer (CRC), typically detected during colonoscopy. However, the variability in appearance, location, and size of these polyps complicates their detection and removal, leading to…

Colorectal cancer from the appearance of polyps that can be benign or malignant is one of the most fatal diseases in the world. To find these polyps in patients, colonoscopy is performed, which is a very efficient technique in this case.…

Image and Video Processing · Electrical Eng. & Systems 2021-03-30 Marcus V. L. Branch , Adriele S. Carvalho

Automatic image-based severity estimation is an important task in computer-aided diagnosis. Severity estimation by deep learning requires a large amount of training data to achieve a high performance. In general, severity estimation uses…

Computer Vision and Pattern Recognition · Computer Science 2024-09-11 Takeaki Kadota , Hideaki Hayashi , Ryoma Bise , Kiyohito Tanaka , Seiichi Uchida

Polyps are well-known cancer precursors identified by colonoscopy. However, variability in their size, location, and surface largely affect identification, localisation, and characterisation. Moreover, colonoscopic surveillance and removal…

Deep learning based neural networks have gained popularity for a variety of biomedical imaging applications. In the last few years several works have shown the use of these methods for colon cancer detection and the early results have been…

Computer Vision and Pattern Recognition · Computer Science 2023-01-24 Chandana Raju , Sumedh Vilas Datar , Kushala Hari , Kavin Vijay , Suma Ningappa

Over 150,000 new people in the United States are diagnosed with colorectal cancer each year. Nearly a third die from it (American Cancer Society). The only approved noninvasive diagnosis tools currently involve fecal blood count tests…

Machine Learning · Statistics 2017-08-16 Anirudh Kamath , Aditya Singh , Raj Ramnani , Ayush Vyas , Jay Shenoy

The tremendous boost in the next generation sequencing and in the omics technologies makes it possible to characterize human gut microbiome (the collective genomes of the microbial community that reside in our gastrointestinal tract). While…

Quantitative Methods · Quantitative Biology 2020-01-10 Hilal Hacilar , O. Ufuk Nalbantoglu , Oya Aran , Burcu Bakir-Gungor

In this study, to address the current high earlydetection miss rate of colorectal cancer (CRC) polyps, we explore the potentials of utilizing transfer learning and machine learning (ML) classifiers to precisely and sensitively classify the…

Image and Video Processing · Electrical Eng. & Systems 2022-11-10 Nethra Venkatayogi , Ozdemir Can Kara , Jeff Bonyun , Naruhiko Ikoma , Farshid Alambeigi

Gastrointestinal mucosal changes can cause cancers after some years and early diagnosing them can be very useful to prevent cancers and early treatment. In this article, 8 classes of mucosal changes and anatomical landmarks including…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Mohammadhasan Goharian , Vahid Goharian , Hamidreza Bolhasani

Colorectal polyps are generally benign alterations that, if not identified promptly and managed successfully, can progress to cancer and cause affectations on the colon mucosa, known as adenocarcinoma. Today advances in Deep Learning have…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Daniela L. Ramos , Hector J. Hortua

Lower urinary tract symptoms (LUTS) can indicate the presence of urinary tract infection (UTI), a condition that if it becomes chronic requires expensive and time consuming care as well as leading to reduced quality of life. Detecting the…

Applications · Statistics 2015-07-13 William Barcella , Maria De Iorio , Gianluca Baio , James Malone-Lee

Deep learning based approaches to Computer Aided Diagnosis (CAD) typically pose the problem as an image classification (Normal or Abnormal) problem. These systems achieve high to very high accuracy in specific disease detection for which…

Computer Vision and Pattern Recognition · Computer Science 2020-10-06 Aniket Joshi , Gaurav Mishra , Jayanthi Sivaswamy