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Efficient and accurate multi-organ segmentation from abdominal CT volumes is a fundamental challenge in medical image analysis. Existing 3D segmentation approaches are computationally and memory intensive, often processing entire volumes…

Model based iterative reconstruction (MBIR) algorithms for low-dose X-ray CT are computationally expensive. To address this problem, we recently proposed a deep convolutional neural network (CNN) for low-dose X-ray CT and won the second…

Recent developments in fluorescence microscopy allow capturing high-resolution 3D images over time for living model organisms. To be able to image even large specimens, techniques like multi-view light-sheet imaging record different…

Medical imaging is limited by acquisition time and scanning equipment. CT and MR volumes, reconstructed with thicker slices, are anisotropic with high in-plane resolution and low through-plane resolution. We reveal an intriguing phenomenon…

Multi-modality (MM) image fusion aims to render fused images that maintain the merits of different modalities, e.g., functional highlight and detailed textures. To tackle the challenge in modeling cross-modality features and decomposing…

Relying on either deep models or physical models are two mainstream approaches for solving inverse sample reconstruction problems in programmable illumination computational microscopy. Solutions based on physical models possess strong…

Recovering the 3D shape of an object from single or multiple images with deep neural networks has been attracting increasing attention in the past few years. Mainstream works (e.g. 3D-R2N2) use recurrent neural networks (RNNs) to…

Model-based optimization methods and discriminative learning methods have been the two dominant strategies for solving various inverse problems in low-level vision. Typically, those two kinds of methods have their respective merits and…

For single source helical Computed Tomography (CT), both Filtered-Back Projection (FBP) and statistical iterative reconstruction have been investigated. However for dual source CT with flying focal spot (DS-FFS CT), statistical iterative…

Brain imaging analysis on clinically acquired computed tomography (CT) is essential for the diagnosis, risk prediction of progression, and treatment of the structural phenotypes of traumatic brain injury (TBI). However, in real clinical…

Performing magnetic resonance imaging (MRI) reconstruction from under-sampled k-space data can accelerate the procedure to acquire MRI scans and reduce patients' discomfort. The reconstruction problem is usually formulated as a denoising…

Multi-contrast MRI images provide complementary contrast information about the characteristics of anatomical structures and are commonly used in clinical practice. Recently, a multi-flip-angle (FA) and multi-echo GRE method (MULTIPLEX MRI)…

MRI and CT are essential clinical cross-sectional imaging techniques for diagnosing complex conditions. However, large 3D datasets with annotations for deep learning are scarce. While methods like DINOv2 are encouraging for 2D image…

Plug-and-Play Priors (PnP) is one of the most widely-used frameworks for solving computational imaging problems through the integration of physical models and learned models. PnP leverages high-fidelity physical sensor models and powerful…

The availability of high-speed 3D video sensors has greatly facilitated 3D shape acquisition of dynamic and deformable objects, but high frame rate 3D reconstruction is always degraded by spatial noise and temporal fluctuations. This paper…

Novel sparse reconstruction algorithms are proposed for beamspace channel estimation in massive multiple-input multiple-output systems. The proposed algorithms minimize a least-squares objective having a nonconvex regularizer. This…

Parallel imaging has been an essential technique to accelerate MR imaging. Nevertheless, the acceleration rate is still limited due to the ill-condition and challenges associated with the undersampled reconstruction. In this paper, we…

A long-standing challenge in tomography is the 'missing wedge' problem, which arises when the acquisition of projection images within a certain angular range is restricted due to geometrical constraints. This incomplete dataset results in…

Deep learning-based 3-dimensional (3D) shape reconstruction from 2-dimensional (2D) magnetic resonance imaging (MRI) has become increasingly important in medical disease diagnosis, treatment planning, and computational modeling. This review…

While convolutional neural networks (CNNs) and vision transformers (ViTs) have advanced medical image segmentation, they face inherent limitations such as local receptive fields in CNNs and high computational complexity in ViTs. This paper…