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Current medical language model (LM) benchmarks often over-simplify the complexities of day-to-day clinical practice tasks and instead rely on evaluating LMs on multiple-choice board exam questions. In psychiatry especially, these challenges…

Monitoring the health status of patients in the Intensive Care Unit (ICU) is a critical aspect of providing superior care and treatment. The availability of large-scale electronic health records (EHR) provides machine learning models with…

Artificial Intelligence · Computer Science 2023-05-05 Jun Wu , Xuesong Ye , Chengjie Mou , Weinan Dai

The ICH E9(R1) Addendum (International Council for Harmonization 2019) suggests treatment-policy as one of several strategies for addressing intercurrent events such as treatment withdrawal when defining an estimand. This strategy requires…

Methodology · Statistics 2023-08-28 Suzie Cro , James H Roger , James R Carpenter

High-throughput microarray and sequencing technology have been used to identify disease subtypes that could not be observed otherwise by using clinical variables alone. The classical unsupervised clustering strategy concerns primarily the…

Methodology · Statistics 2020-07-23 Peng Liu , Yusi Fang , Zhao Ren , Lu Tang , George C. Tseng

In the dynamic hospital setting, decision support can be a valuable tool for improving patient outcomes. Data-driven inference of future outcomes is challenging in this dynamic setting, where long sequences such as laboratory tests and…

Quantitative Methods · Quantitative Biology 2024-04-25 Alan D. Kaplan , Priyadip Ray , John D. Greene , Vincent X. Liu

Clinician scheduling remains a persistent challenge due to limited clinical resources and fluctuating demands. This complexity is especially acute in large academic anesthesiology departments as physicians balance responsibilities across…

Optimization and Control · Mathematics 2025-10-03 Anjali Jha , Wanqing Chen , Maxim Eckmann , Ian Stockwell , Jianwu Wang , Kai Sun

The sequential treatment decisions made by physicians to treat chronic diseases are formalized in the statistical literature as dynamic treatment regimes. To date, methods for dynamic treatment regimes have been developed under the…

Methodology · Statistics 2022-02-22 Janie Coulombe , Erica E. M. Moodie , Susan M. Shortreed , Christel Renoux

Many deep learning based automated medical image segmentation systems, in reality, face difficulties in deployment due to the cost of massive data annotation and high latency in model iteration. We propose a dynamic interactive learning…

Computer Vision and Pattern Recognition · Computer Science 2023-12-12 Mu Tian , Xiaohui Chen , Yi Gao

Dynamic assessment of patient status (e.g. by an automated, continuously updated assessment of outcome) in the Intensive Care Unit (ICU) is of paramount importance for early alerting, decision support and resource allocation. Extraction and…

Machine Learning · Computer Science 2019-09-20 Jacob Deasy , Ari Ercole , Pietro Liò

Regular documentation of progress notes is one of the main contributors to clinician burden. The abundance of structured chart information in medical records further exacerbates the burden, however, it also presents an opportunity to…

Computation and Language · Computer Science 2024-10-18 Sarvesh Soni , Dina Demner-Fushman

Feature engineering remains a major bottleneck when creating predictive systems from electronic medical records. At present, an important missing element is detecting predictive regular clinical motifs from irregular episodic records. We…

Machine Learning · Statistics 2016-07-27 Phuoc Nguyen , Truyen Tran , Nilmini Wickramasinghe , Svetha Venkatesh

Optimization of patient throughput and wait time in emergency departments (ED) is an important task for hospital systems. For that reason, Emergency Severity Index (ESI) system for patient triage was introduced to help guide manual…

Computers and Society · Computer Science 2018-04-11 Djordje Gligorijevic , Jelena Stojanovic , Wayne Satz , Ivan Stojkovic , Kathrin Schreyer , Daniel Del Portal , Zoran Obradovic

Deep learning-based health status representation learning and clinical prediction have raised much research interest in recent years. Existing models have shown superior performance, but there are still several major issues that have not…

Machine Learning · Computer Science 2019-11-28 Liantao Ma , Junyi Gao , Yasha Wang , Chaohe Zhang , Jiangtao Wang , Wenjie Ruan , Wen Tang , Xin Gao , Xinyu Ma

This study proposes a novel, integrative framework for patient-centered data science in the digital health era. We developed a multidimensional model that combines traditional clinical data with patient-reported outcomes, social…

Machine Learning · Computer Science 2024-08-07 Mohsen Amoei , Dan Poenaru

Medical report generation is a critical task in healthcare that involves the automatic creation of detailed and accurate descriptions from medical images. Traditionally, this task has been approached as a sequence generation problem,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Yijian Fan , Zhenbang Yang , Rui Liu , Mingjie Li , Xiaojun Chang

Neural network representation learning frameworks have recently shown to be highly effective at a wide range of tasks ranging from radiography interpretation via data-driven diagnostics to clinical decision support. This often superior…

Information Retrieval · Computer Science 2018-11-14 Xing Wei , Carsten Eickhoff

Estimation of individual treatment effects is commonly used as the basis for contextual decision making in fields such as healthcare, education, and economics. However, it is often sufficient for the decision maker to have estimates of…

Machine Learning · Computer Science 2020-08-13 Maggie Makar , Fredrik D. Johansson , John Guttag , David Sontag

Medical researchers are coming to appreciate that many diseases are in fact complex, heterogeneous syndromes composed of subpopulations that express different variants of a related complication. Time series data extracted from individual…

Machine Learning · Statistics 2016-06-30 Peter Schulam , Raman Arora

Monitoring the health status of patients and predicting mortality in advance is vital for providing patients with timely care and treatment. Massive medical signs in electronic health records (EHR) are fitted into advanced machine learning…

Machine Learning · Computer Science 2023-11-07 Xuesong Ye , Jun Wu , Chengjie Mou , Weinan Dai

The scientific literature is growing exponentially, and professionals are no more able to cope with the current amount of publications. Text mining provided in the past methods to retrieve and extract information from text; however, most of…

Computation and Language · Computer Science 2019-02-27 Nikola Milosevic , Cassie Gregson , Robert Hernandez , Goran Nenadic
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