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Threshold-linear networks (TLNs) are models of neural networks that consist of simple, perceptron-like neurons and exhibit nonlinear dynamics that are determined by the network's connectivity. The fixed points of a TLN, including both…

Neurons and Cognition · Quantitative Biology 2018-08-06 Carina Curto , Jesse Geneson , Katherine Morrison

Neural network models in neuroscience allow one to study how the connections between neurons shape the activity of neural circuits in the brain. In this chapter, we study Combinatorial Threshold-Linear Networks (CTLNs) in order to…

Neurons and Cognition · Quantitative Biology 2018-04-05 Katherine Morrison , Carina Curto

Combinatorial threshold-linear networks (CTLNs) are a special class of inhibition-dominated TLNs defined from directed graphs. Like more general TLNs, they display a wide variety of nonlinear dynamics including multistability, limit cycles,…

Neurons and Cognition · Quantitative Biology 2022-08-16 Caitlyn Parmelee , Samantha Moore , Katherine Morrison , Carina Curto

To any inhibition-dominated threshold-linear network (TLN) we can associate a directed graph that captures the pattern of strong and weak inhibition between neurons. Robust motifs are graphs for which the structure of fixed points in the…

Neurons and Cognition · Quantitative Biology 2019-12-18 Carina Curto , Christopher Langdon , Katherine Morrison

Nonlinear network dynamics are notoriously difficult to understand. Here we study a class of recurrent neural networks called combinatorial threshold-linear networks (CTLNs) whose dynamics are determined by the structure of a directed…

Neurons and Cognition · Quantitative Biology 2021-09-16 Daniela Egas Santander , Stefania Ebli , Alice Patania , Nicole Sanderson , Felicia Burtscher , Katherine Morrison , Carina Curto

Combinatorial threshold-linear networks (CTLNs) are a special class of recurrent neural networks whose dynamics are tightly controlled by an underlying directed graph. Recurrent networks have long been used as models for associative memory…

Neurons and Cognition · Quantitative Biology 2023-11-21 Carina Curto , Jesse Geneson , Katherine Morrison

This dissertation explores applications of discrete geometry in mathematical neuroscience. We begin with convex neural codes, which model the activity of hippocampal place cells and other neurons with convex receptive fields. In Chapter 4,…

Neurons and Cognition · Quantitative Biology 2022-09-19 Caitlin Lienkaemper

Threshold-linear networks consist of simple units interacting in the presence of a threshold nonlinearity. Competitive threshold-linear networks have long been known to exhibit multistability, where the activity of the network settles into…

Neurons and Cognition · Quantitative Biology 2023-10-17 Katherine Morrison , Anda Degeratu , Vladimir Itskov , Carina Curto

Networks of interconnected neurons display diverse patterns of collective activity. Relating this collective activity to the network's connectivity structure is a key goal of computational neuroscience. We approach this question for…

Neurons and Cognition · Quantitative Biology 2025-06-09 Caitlin Lienkaemper , Gabriel Koch Ocker

Sequences of neural activity arise in many brain areas, including cortex, hippocampus, and central pattern generator circuits that underlie rhythmic behaviors like locomotion. While network architectures supporting sequence generation vary…

Neurons and Cognition · Quantitative Biology 2022-08-16 Caitlyn Parmelee , Juliana Londono Alvarez , Carina Curto , Katherine Morrison

Threshold-linear networks are a common class of firing rate models that describe recurrent interactions among neurons. Unlike their linear counterparts, these networks generically possess multiple stable fixed points (steady states), making…

Neurons and Cognition · Quantitative Biology 2016-12-28 Carina Curto , Katherine Morrison

The relationship between the properties of a dynamical system and the structure of its defining equations has long been studied in many contexts. Here we study this problem for the class of conjunctive (resp. disjunctive) Boolean networks,…

Combinatorics · Mathematics 2008-05-13 Abdul Salam Jarrah , Reinhard Laubenbacher , Alan Veliz-Cuba

Boolean threshold networks have recently been proposed as useful tools to model the dynamics of genetic regulatory networks, and have been successfully applied to describe the cell cycles of \textit{S. cerevisiae} and \textit{S. pombe}.…

Chaotic Dynamics · Physics 2010-11-18 Jorge G. T. Zañudo , Maximino Aldana , Gustavo Martínez-Mekler

The understanding of neural activity patterns is fundamentally linked to an understanding of how the brain's network architecture shapes dynamical processes. Established approaches rely mostly on deviations of a given network from certain…

Neurons and Cognition · Quantitative Biology 2014-09-19 Marc-Thorsten Huett , Marcus Kaiser , Claus C. Hilgetag

While modern deep networks have demonstrated remarkable versatility, their training dynamics remain poorly understood--often driven more by empirical tweaks than architectural insight. This paper investigates how internal structural choices…

Machine Learning · Computer Science 2025-08-26 Saleh Nikooroo , Thomas Engel

In machine learning, there is a fundamental trade-off between ease of optimization and expressive power. Neural Networks, in particular, have enormous expressive power and yet are notoriously challenging to train. The nature of that…

Machine Learning · Computer Science 2015-11-24 Diogo Almeida , Nate Sauder

This paper investigates how the compositional structure of neural networks shapes their optimization landscape and training dynamics. We analyze the gradient flow associated with overparameterized optimization problems, which can be…

Machine Learning · Computer Science 2025-11-14 Arthur Castello Branco de Oliveira , Dhruv Jatkar , Eduardo Sontag

We leverage the framework of hyperplane arrangements to analyze potential regions of (stable) fixed points. We provide an upper bound on the number of fixed points for multi-layer neural networks equipped with piecewise linear (PWL)…

Machine Learning · Computer Science 2024-07-16 Hans-Peter Beise

Artificial neural networks used for reinforcement learning are structurally rigid, meaning that each optimized parameter of the network is tied to its specific placement in the network structure. It also means that a network only works with…

Neural and Evolutionary Computing · Computer Science 2024-05-20 Joachim Winther Pedersen , Erwan Plantec , Eleni Nisioti , Milton Montero , Sebastian Risi

Understanding how learning algorithms shape the computational strategies that emerge in neural networks remains a fundamental challenge in machine intelligence. While network architectures receive extensive attention, the role of the…

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