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Our knowledge of the sensory world is encoded by neurons in sequences of discrete, identical pulses termed action potentials or spikes. There is persistent controversy about the extent to which the precise timing of these spikes is relevant…

Neurons and Cognition · Quantitative Biology 2007-05-23 Ilya Nemenman , Geoffrey D. Lewen , William Bialek , Rob R. de Ruyter van Steveninck

It is widely accepted that the brain operates near a critical state, characterized by neural avalanches that follow power-law distributions. However, the functional rationale for why neural systems attain criticality remains unclear. Here,…

Neurons and Cognition · Quantitative Biology 2026-05-22 He Xiao , Xinyue Zhao , Weikang Wang

We have developed an efficient information-maximization method for computing the optimal shapes of tuning curves of sensory neurons by optimizing the parameters of the underlying feedforward network model. When applied to the problem of…

Information Theory · Computer Science 2017-02-03 Wentao Huang , Xin Huang , Kechen Zhang

Mixture-of-Experts models are commonly used when there exist distinct clusters with different relationships between the independent and dependent variables. Fitting such models for large datasets, however, is computationally virtually…

Methodology · Statistics 2023-09-06 Yanxi Liu , John Stufken , Min Yang

Although Shannon mutual information has been widely used, its effective calculation is often difficult for many practical problems, including those in neural population coding. Asymptotic formulas based on Fisher information sometimes…

Information Theory · Computer Science 2019-03-06 Wentao Huang , Kechen Zhang

Many real-world tasks include some kind of parameter estimation, i.e., determination of a parameter encoded in a probability distribution. Often, such probability distributions arise from stochastic processes. For a stationary stochastic…

Quantum Physics · Physics 2023-06-08 Marco Radaelli , Gabriel T. Landi , Kavan Modi , Felix C. Binder

The conventional formulation of quantum sensing is based on the assumption that the probe is reset to its initial state after each measurement. In a very distinct approach, one can also pursue a sequential measurement scheme in which…

Quantum Physics · Physics 2023-08-08 Yaoling Yang , Victor Montenegro , Abolfazl Bayat

In the brain, information is encoded, transmitted and used to inform behaviour at the level of timing of action potentials distributed over population of neurons. To implement neural-like systems in silico, to emulate neural function, and…

Neural and Evolutionary Computing · Computer Science 2022-12-09 Stefano Panzeri , Ella Janotte , Alejandro Pequeño-Zurro , Jacopo Bonato , Chiara Bartolozzi

Sparse coding refers to the pursuit of the sparsest representation of a signal in a typically overcomplete dictionary. From a Bayesian perspective, sparse coding provides a Maximum a Posteriori (MAP) estimate of the unknown vector under a…

Signal Processing · Electrical Eng. & Systems 2019-09-04 Dror Simon , Jeremias Sulam , Yaniv Romano , Yue M. Lu , Michael Elad

A simple sparse coding mechanism appears in the sensory systems of several organisms: to a coarse approximation, an input $x \in \R^d$ is mapped to much higher dimension $m \gg d$ by a random linear transformation, and is then sparsified by…

Neural and Evolutionary Computing · Computer Science 2020-06-09 Sanjoy Dasgupta , Christopher Tosh

Mammalian spatial navigation relies on specialized neurons, such as place and grid cells, which encode position based on self-motion and environmental cues. While extensive research has explored the computational role of grid cells, the…

Neurons and Cognition · Quantitative Biology 2026-03-02 Jared Deighton , Wyatt Mackey , Ioannis Schizas , David L. Boothe , Vasileios Maroulas

Neural populations encode information about their stimulus in a collective fashion, by joint activity patterns of spiking and silence. A full account of this mapping from stimulus to neural activity is given by the conditional probability…

Neurons and Cognition · Quantitative Biology 2013-06-14 Einat Granot-Atedgi , Gašper Tkačik , Ronen Segev , Elad Schneidman

The human brain utilizes spikes for information transmission and dynamically reorganizes its network structure to boost energy efficiency and cognitive capabilities throughout its lifespan. Drawing inspiration from this spike-based…

Human-Computer Interaction · Computer Science 2025-02-20 Jiangrong Shen , Qi Xu , Gang Pan , Badong Chen

The brain, which uses redundancy and continuous learning to overcome the unreliability of its components, provides a promising path to building computing systems that are robust to the unreliability of their constituent nanodevices. In this…

Emerging Technologies · Computer Science 2018-10-17 Alice Mizrahi , Julie Grollier , Damien Querlioz , M. D. Stiles

In this contribution, quantum Fisher information is utilized to estimate the parameters of a central qubit interacting with a single-spin qubit. The effect of the longitudinal, transverse and the rotating strengths of the magnetic field on…

Quantum Physics · Physics 2018-04-04 N. Metwally

In this paper, we study an asymptotic approximation of the Fisher information for the estimation of a scalar parameter using quantized measurements. We show that, as the number of quantization intervals tends to infinity, the loss of Fisher…

Information Theory · Computer Science 2013-10-28 Rodrigo Cabral Farias , Jean-Marc Brossier

The estimation of continuous parameters from measured data plays a central role in many fields of physics. A key tool in understanding and improving such estimation processes is the concept of Fisher information, which quantifies how…

We examine the connection between training error and generalization error for arbitrary estimating procedures, working in an overparameterized linear model under general priors in a Bayesian setup. We find determining factors inherent to…

Machine Learning · Statistics 2026-02-11 Chen Cheng , Rina Foygel Barber

There is increasing realization in neuroscience that information is represented in the brain, e.g., neocortex, hippocampus, in the form sparse distributed codes (SDCs), a kind of cell assembly. Two essential questions are: a) how are such…

Machine Learning · Computer Science 2020-10-22 Rod Rinkus

In humans and other animals, category learning enhances discrimination between stimuli close to the category boundary. This phenomenon, called categorical perception, was also empirically observed in artificial neural networks trained on…

Machine Learning · Computer Science 2025-11-27 Laurent Bonnasse-Gahot , Jean-Pierre Nadal