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Involuntary motion during weight-bearing cone-beam computed tomography (CT) scans of the knee causes artifacts in the reconstructed volumes making them unusable for clinical diagnosis. Currently, image-based or marker-based methods are…

Computer Vision and Pattern Recognition · Computer Science 2020-10-22 Jennifer Maier , Marlies Nitschke , Jang-Hwan Choi , Garry Gold , Rebecca Fahrig , Bjoern M. Eskofier , Andreas Maier

The raw BRITE photometry is affected by the presence of many outliers and instrumental effects. We present and discuss possible ways to correct the photometry for instrumental effects. Special attention is paid to the procedure of…

Instrumentation and Methods for Astrophysics · Physics 2018-01-26 Andrzej Pigulski

Optical Coherence Tomography (OCT) is a non-invasive depth resolved optical imaging modality, that enables high resolution, cross-sectional imaging in biological tissues and materials at clinically relevant depths. Though OCT offers high…

Medical Physics · Physics 2020-05-29 Cerine Lal , Sergey Alexandrov , Sweta Rani , Yi Zhou , Thomas Ritter , Martin Leahy

Throughout the process of aging, deterioration of bone macro- and micro-architecture, as well as material decomposition result in a loss of strength and therefore in an increased likelihood of fractures. To date, precise contributions of…

Quantitative Methods · Quantitative Biology 2020-02-19 Pouyan Asgharzadeh , Oliver Röhrle , Bettina M. Willie , Annette I. Birkhold

Significance: Multiple eye diseases such as age-related macular degeneration, diabetic retinopathy, and retinitis pigmentosa can cause photoreceptor dysfunction. Rod photoreceptors are known to be more vulnerable than cone photoreceptors.…

Biological Physics · Physics 2022-12-21 Jie Ding , Tae-Hoon Kim , Guangying Ma , Xincheng Yao

Currently, free flaps and pedicled flaps are assessed for reperfusion in post-operative care using colour, capillary refill, temperature, texture and Doppler signal (if available). While these techniques are effective, they are prone to…

Medical Physics · Physics 2022-04-18 Mark Main , Richard JJ Pilkington , Graham M Gibson , Akhil Kallepalli

Intracortical US imaging extends B-mode imaging into bone using a dedicated image reconstruction algorithm that corrects for refraction at the bone-soft tissue interfaces. It has shown promising results in a few healthy, predominantly young…

Medical Physics · Physics 2025-02-14 Amadou S. Dia , Guillaume Renaud , Christine Chappard , Quentin Grimal

Noninvasive, non-contact and \textit{in vivo} monitoring of blood glucose is a long needed pathology tool for saving patients from recurring pain and hassle that can accompany conventional blood glucose testing methods. Optical coherence…

Biological Physics · Physics 2008-08-04 R Poddar , S R Sharma , P Sen , J T Andrews

Inverse scattering in optical coherence tomography (OCT) seeks to recover both structural images and intrinsic tissue optical properties, including refractive index, scattering coefficient, and anisotropy. This inverse problem is…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Jinglun Yu , Yaning Wang , Wenhan Guo , Yuan Gao , Yu Sun , Jin U. Kang

Blunt traumatic aortic rupture is a heart injury that can occur in falls, automobile accidents, and sporting injuries involving impact to the thorax. Despite its severity and high morbidity rate, the research still does not provide a…

This paper investigates the use of Optical Coherence Tomography (OCT) and Short-wave Infrared (SWIR) spectral imaging to study the deterioration of a Limoges enamel panel. Limoges enamels are formed of glass layers applied on a metal…

Corneal thickness (pachymetry) maps can be used to monitor restoration of corneal endothelial function, for example after Descemet's membrane endothelial keratoplasty (DMEK). Automated delineation of the corneal interfaces in anterior…

We introduce CartiMorph, a framework for automated knee articular cartilage morphometrics. It takes an image as input and generates quantitative metrics for cartilage subregions, including the percentage of full-thickness cartilage loss…

Image and Video Processing · Electrical Eng. & Systems 2023-11-22 Yongcheng Yao , Junru Zhong , Liping Zhang , Sheheryar Khan , Weitian Chen

Plain radiography is the most common modality to assess the stage of osteoarthritis. Our aims were to assess the relationship of radiography-based bone density and texture between radiographs with minimal and clinical post-processing, and…

Medical Physics · Physics 2019-02-07 Jukka Hirvasniemi , Jaakko Niinimäki , Jérôme Thevenot , Simo Saarakkala

Plastic scintillators are a versatile and inexpensive option for particle detection, which is why the largest particle physics experiments, CMS and ATLAS, use them extensively in their calorimeters. One of their challenging aspects,…

Instrumentation and Detectors · Physics 2023-12-11 C. Papageorgakis , M. Y. Aamir , A. Belloni , T. K. Edberg , S. C. Eno , B. Kronheim , C. Palmer

Injuries to articular cartilage result in the development of lesions that form on the surface of the cartilage. Such lesions are associated with articular cartilage degeneration and osteoarthritis. The typical injury response often causes…

Tissues and Organs · Quantitative Biology 2011-09-08 Jason M. Graham , Bruce P. Ayati , Lei Ding , Prem S. Ramakrishnan , James A. Martin

Exudative (wet) age-related macular degeneration (AMD) is a leading cause of vision loss in older adults, typically treated with intravitreal injections. Emerging therapies, such as subretinal injections of stem cells, gene therapy, small…

A Coulomb-excitation reorientation-effect measurement using the TIGRESS $\gamma-$ray spectrometer at the TRIUMF/ISAC II facility has permitted the first determination of the $\langle 2^+_1\mid\mid \hat{E2} \mid\mid 2^+_1\rangle$ diagonal…

Accurate assessment of corneal mechanical properties is critical for understanding ocular biomechanics, predicting refractive surgery outcomes, and optimizing cross-linking (CXL) treatments. Conventional uniaxial tensile test is limited by…

Objective: To establish an automated pipeline for post-processing of quantitative spin-lattice relaxation time constant in the rotating frame ($T_{1\rho}$) imaging of knee articular cartilage. Design: The proposed post-processing pipeline…

Image and Video Processing · Electrical Eng. & Systems 2024-09-20 Junru Zhong , Yongcheng Yao , Fan Xiao , Tim-Yun Michael Ong , Ki-Wai Kevin Ho , Siyue Li , Chaoxing Huang , Queenie Chan , James F. Griffith , Weitian Chen