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Mid-infrared spectroscopic imaging (MIRSI) is an emerging class of label-free techniques being leveraged for digital histopathology. Modern histopathologic identification of ovarian cancer involves tissue staining followed by morphological…

Ovarian cancer detection has traditionally relied on a multi-step process that includes biopsy, tissue staining, and morphological analysis by experienced pathologists. While widely practiced, this conventional approach suffers from several…

Label-free and nondestructive mid-infrared vibrational hyperspectral imaging is emerging as an important ex-vivo tissue analysis tool, providing spatially resolved biochemical information critical to understanding physiological and…

Mid-infrared (MIR) spectroscopy is widely recognized as a powerful, non-distractive method for chemical analysis. However, its utility is constrained by a micrometer-scale spatial resolution imposed by the long-wavelength MIR diffraction…

Fourier-transform infrared spectroscopy (FTIR) is the golden standard of mid-infrared (MIR) molecular spectroscopic analysis through optically-encoded vibrational signatures. Michelson-type FTIR and MIR dual-comb spectrometers allow us to…

Optics · Physics 2025-05-06 Kazuki Hashimoto , Venkata Ramaiah Badarla , Takuro Ideguchi

The emerging technique of mid-infrared optical coherence tomography (MIR-OCT) takes advantage of the reduced scattering of MIR light in various materials and devices, enabling tomographic imaging at deeper penetration depths. Because of…

Mid-InfraRed spectroscopy is a promising label-free technique that can offer insights into morphological and pathological alterations in biological tissues at the molecular level. Owing to the development of the Fourier Transform InfraRed…

Optics · Physics 2026-04-21 Xiangyu Zhao , Yudong Tian , Jingzhu Shao , Chongzhao Wu

Nano-FTIR imaging is a powerful scanning-based technique at nanometer spatial resolution which combines Fourier transform infrared spectroscopy (FTIR) and scattering-type scanning near-field optical microscopy (s-SNOM). However, recording…

High-dimensional hyperspectral imaging (HSI) enables the visualization of ultrafast molecular dynamics and complex, heterogeneous spectra. However, applying this capability to resolve spatially varying vibrational couplings in…

Image and Video Processing · Electrical Eng. & Systems 2026-04-09 Chi-Jui Ho , Harsh Bhakta , Wei Xiong , Nicholas Antipa

Fourier single-pixel imaging (FSI) is a branch of single-pixel imaging techniques. It uses Fourier basis patterns as structured patterns for spatial information acquisition in the Fourier domain. However, the spatial resolution of the image…

Image and Video Processing · Electrical Eng. & Systems 2021-08-06 Ziheng Qiu , Xinyi Guo , Tianao Lu , Pan Qi , Zibang Zhang , Jingang Zhong

Fourier Transform Interferometry (FTI) is an appealing Hyperspectral (HS) imaging modality for many applications demanding high spectral resolution, e.g., in fluorescence microscopy. However, the effective resolution of FTI is limited by…

Information Theory · Computer Science 2019-01-31 A. Moshtaghpour , L. Jacques , V. Cambareri , P. Antoine , M. Roblin

Mid-wave infrared (MWIR) cameras for large number pixels are extremely expensive compared with their counterparts in visible light, thus, super-resolution imaging (SRI) for MWIR by increasing imaging pixels has always been a research…

Image and Video Processing · Electrical Eng. & Systems 2025-03-19 Xiao-Peng Jin , Qing Zhao , Xue-Feng Liu , An-Dong Xiong

Fourier-transform infrared spectroscopy (FTIR) is a powerful analytical method for not only the chemical identification of solid, liquid, and gas species, but also the quantification of their concentration. However, the chemical…

Spectral imaging in the mid-infrared (MIR) range provides simultaneous morphological and chemical information of a wide variety of samples. However, current MIR technologies struggle to produce high-definition images over a broad spectral…

Single-pixel imaging, with the advantages of a wide spectrum, beyond-visual-field imaging, and robustness to light scattering, has attracted increasing attention in recent years. Fourier single-pixel imaging (FSI) can reconstruct sharp…

Image and Video Processing · Electrical Eng. & Systems 2021-08-05 Dong Zhou , Jie Cao , Huan Cui , Qun Hao , Bing-Kun Chen , Kai Lin

Photothermal microscopy is an emerging tool for measuring light-matter interactions with single-molecule sensitivity. It is generally believed that the spectral acquisition speed in photothermal microscopy is limited by the slow thermal…

This paper presents an adaptive and intelligent sparse model for digital image sampling and recovery. In the proposed sampler, we adaptively determine the number of required samples for retrieving image based on space-frequency-gradient…

Computer Vision and Pattern Recognition · Computer Science 2017-11-27 Ali Taimori , Farokh Marvasti

Hyperspectral imaging (HSI) is an advanced sensing modality that simultaneously captures spatial and spectral information, enabling non-invasive, label-free analysis of material, chemical, and biological properties. This Primer presents a…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Danfeng Hong , Chenyu Li , Naoto Yokoya , Bing Zhang , Xiuping Jia , Antonio Plaza , Paolo Gamba , Jon Atli Benediktsson , Jocelyn Chanussot

Quasiparticle interference imaging (QPI) offers insight into the band structure of quantum materials from the Fourier transform of local density of states (LDOS) maps. Their acquisition with a scanning tunneling microscope is traditionally…

We demonstrate instrumentation and methods to enable fluorescence-detected photothermal infrared (F-PTIR) microscopy, then demonstrate the utility of F-PTIR to characterize the composition within phase-separated domains of model amorphous…

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