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Current theories suggest that adaptive decision-making necessitates the interaction between multiple decision-making systems. The computational definitions of different models of decision-making suggest interactions with task demands and…

Neurons and Cognition · Quantitative Biology 2023-07-28 Ugurcan Mugan , Seiichiro Amemiya , Paul S. Regier , A. David Redish

Synaptic plasticity allows cortical circuits to learn new tasks and to adapt to changing environments. How do cortical circuits use plasticity to acquire functions such as decision-making or working memory? Neurons are connected in complex…

Neurons and Cognition · Quantitative Biology 2023-03-08 Néstor Parga , Luis Serrano-Fernández , Joan Falcó-Roget

Understanding how decision making changes across the lifespan is a central challenge for neuroscience, yet research on cognitive aging has remained largely disconnected from the theoretical and computational advances that now shape modern…

Neurons and Cognition · Quantitative Biology 2026-03-04 Michael B. Ryan , Letizia Ye , Anne K. Churchland

A central goal of evolutionary biology is to explain the origins and distribution of diversity across life. Beyond species or genetic diversity, we also observe diversity in the circuits (genetic or otherwise) underlying complex functional…

Populations and Evolution · Quantitative Biology 2018-06-06 Ali Tehrani-Saleh , Thomas LaBar , Christoph Adami

This paper describes a relatively simple way of allowing a brain model to self-organise its concept patterns through nested structures. For a simulation, time reduction is helpful and it would be able to show how patterns may form and then…

Artificial Intelligence · Computer Science 2015-03-17 Kieran Greer

The increasing interest in understanding the behavior of the biological neural networks, and the increasing utilization of artificial neural networks in different fields and scales, both require a thorough understanding of how neuromorphic…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-05-12 János Végh , Ádám J. Berki

Computational modeling plays an increasingly important role in neuroscience, highlighting the philosophical question of how computational models explain. In the context of neural network models for neuroscience, concerns have been raised…

Neurons and Cognition · Quantitative Biology 2021-04-15 Rosa Cao , Daniel Yamins

Neural-network models of high-level brain functions such as memory recall and reasoning often rely on the presence of stochasticity. The majority of these models assumes that each neuron in the functional network is equipped with its own…

Neurons and Cognition · Quantitative Biology 2022-05-17 Jakob Jordan , Mihai A. Petrovici , Oliver Breitwieser , Johannes Schemmel , Karlheinz Meier , Markus Diesmann , Tom Tetzlaff

Neurons in the brain communicate with spikes, which are discrete events in time and value. Functional network models often employ rate units that are continuously coupled by analog signals. Is there a qualitative difference implied by these…

Disordered Systems and Neural Networks · Physics 2021-07-20 Christian Keup , Tobias Kühn , David Dahmen , Moritz Helias

A natural phenomenon occurring in a living system is an outcome of the dynamics of the specific biological network underlying the phenomenon. The collective dynamics have both deterministic and stochastic components. The stochastic nature…

Statistical Mechanics · Physics 2023-09-01 Indrani Bose

Redundancy is a ubiquitous property of the nervous system. This means that vastly different configurations of cellular and synaptic components can enable the same neural circuit functions. However, until recently very little brain disorder…

Neurons and Cognition · Quantitative Biology 2021-02-08 Beatriz E. P. Mizusaki , Cian O'Donnell

The discovery of neural plasticity has proved that throughout the life of a human being, the brain reorganizes itself through forming new neural connections. The formation of new neural connections are achieved through the brain's effort to…

Neurons and Cognition · Quantitative Biology 2020-08-10 Soaad Hossain

The brain can be considered as a system that dynamically optimizes the structure of anatomical connections based on the efficiency requirements of functional connectivity. To illustrate the power of this principle in organizing the…

Neurons and Cognition · Quantitative Biology 2024-02-07 Carlos Calvo Tapia , Valeriy A. Makarov Slizneva , Cees van Leeuwen

Neurons in the brain are often finely tuned for specific task variables. Moreover, such disentangled representations are highly sought after in machine learning. Here we mathematically prove that simple biological constraints on neurons,…

Neurons and Cognition · Quantitative Biology 2023-04-04 James C. R. Whittington , Will Dorrell , Surya Ganguli , Timothy E. J. Behrens

We discuss methods for visualizing neural network decision boundaries and decision regions. We use these visualizations to investigate issues related to reproducibility and generalization in neural network training. We observe that changes…

Shedding light onto how biological systems represent, process and store information in noisy environments is a key and challenging goal. A stimulating, though controversial, hypothesis poses that operating in dynamical regimes near the edge…

Disordered Systems and Neural Networks · Physics 2021-07-14 Guillermo B. Morales , Miguel A. Muñoz

The informational synthesis of neural structures, processes, parameters and characteristics that allow a unified description and modeling as neural machines of natural and artificial neural systems is presented. The general informational…

Neural and Evolutionary Computing · Computer Science 2024-04-08 Iosif Iulian Petrila

It is becoming increasingly appreciated that the signal transduction systems used by eukaryotic cells to achieve a variety of essential responses represent highly complex networks rather than simple linear pathways. While significant effort…

Molecular Networks · Quantitative Biology 2009-11-10 Kevin S. Brown , Colin C. Hill , Guillermo A. Calero , Kelvin H. Lee , James P. Sethna , Richard A. Cerione

A fundamental question in neuroscience is how structure and function of neural systems are related. We study this interplay by combining a familiar auto-associative neural network with an evolving mechanism for the birth and death of…

Adaptation and Self-Organizing Systems · Physics 2019-04-26 Ana P. Millán , J. J. Torres , S. Johnson , J. Marro

Neural activity fluctuates over a wide range of timescales within and across brain areas. Experimental observations suggest that diverse neural timescales reflect information in dynamic environments. However, how timescales are defined and…

Neurons and Cognition · Quantitative Biology 2026-01-21 Roxana Zeraati , Anna Levina , Jakob H. Macke , Richard Gao