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Poly(N-isopropylacrylamide) (pNIPAM) microgels are renowned for their thermoresponsive behavior, exhibiting a distinct volume phase transition (VPT) upon temperature changes. This study investigates the influence of microgel softness,…

Soft Condensed Matter · Physics 2024-08-06 Syamjith KS , Shubhasmita Rout , Alan R Jacob

Hollow microgels, consisting of a pNIPAM polymer network with a central cavity, have significant potential due to their tunable softness and encapsulation capabilities. Using molecular dynamics simulations, we thoroughly characterise the…

Soft Condensed Matter · Physics 2025-04-28 Leah Rank , Emanuela Zaccarelli

A low-temperature dynamical transition has been reported in several proteins. We provide the first observation of a `protein-like' dynamical transition in nonbiological aqueous environments. To this aim we exploit the popular colloidal…

The thermosensitive behavior of microgel particles suspended in solvents, i.e. their temperature-dependent swelling properties, has triggered ongoing interest in industry and academia over the past forty years. The most-studied polymer is…

Soft Condensed Matter · Physics 2026-04-23 Domenico Truzzolillo , Thomas Hellweg , Julian Oberdisse

The thermosensitivity and microstructure of microgels made by copolymerizing standard microgel-forming monomers with more hydrophilic comonomers is investigated, with the aim of increasing the volume phase transition temperature (VPTT). We…

Thermo-responsive microgel particles can exhibit a drastic volume shrinkage upon increasing the solvent temperature. Recently we found that the spreading of poly(N-isopropylacrylamide)(PNiPAm) microgels at a liquid interface under the…

The volume phase transition of microgels is one of the most paradigmatic examples of stimuli-responsiveness, enabling a collapse from a highly swollen microgel state into a densely coiled state by an external stimulus. Although well…

Soft Condensed Matter · Physics 2019-08-16 Johannes Harrer , Marcel Rey , Simone Ciarella , Hartmut Löwen , Liesbeth M. C. Janssen , Nicolas Vogel

Interpenetrated Polymer Network (IPN) microgels of PNIPAM and PAAc have been investigated and the experimental data have been compared with theoretical models from the Flory-Rehner theory. We confirm that the swelling behavior of PNIPAM…

Soft Condensed Matter · Physics 2019-06-24 Valentina Nigro , Roberta Angelini , Monica Bertoldo , Barbara Ruzicka

Temperature-sensitive hydrogels based on polymers such as poly(N-isopropylacrylamide) (PNIPAM) undergo a volume phase transition in response to changes in temperature. During this transition, distinct changes in both thermal and mechanical…

Soft Condensed Matter · Physics 2017-07-19 Frank J. Aangenendt , Johan Mattsson , Wouter G. Ellenbroek , Hans M. Wyss

Microgel suspensions of Interpenetrated Polymer Network (IPN) of PNIPAM and PAAc in D$_2$O, have been investigated through dynamic light scattering as a function of temperature, pH and concentration across the Volume Phase Transition (VPT).…

Colloidal microgel particles such as poly(N-isopropylacrylamide) (PNIPAM) shrink reversibly in an aqueous medium due to the expulsion of water at a volume phase transition temperature, VPTT $\sim$33$^\circ$C. Romeo et al. [Adv. Mater. 2010,…

Soft Condensed Matter · Physics 2025-11-06 Sayantan Chanda , Chandeshwar Misra , Ranjini Bandyopadhyay

Poly(N-isopropylacrylamide) (PNIPAM) is a temperature-responsive polymer that undergoes large volumetric deformations through a transition from a swollen to a collapsed state at the volume phase transition temperature (VPTT). Locally, these…

Soft Condensed Matter · Physics 2025-12-23 Noy Cohen

We investigated the complexation of thermoresponsive anionic poly(N-isopropylacrylamide) (PNiPAM) microgels and cationic $\epsilon$-polylysine ($\epsilon$-PLL) chains. By combining electrophoresis, light scattering, transmission electron…

Thermoresponsive microgels are one of the most investigated class of soft colloids, thanks to their ability to undergo a Volume Phase Transition (VPT) close to ambient temperature. However, this fundamental phenomenon still lacks a detailed…

Thermoresponsive hydrogels exhibit reversible deswelling at the Volume Phase Transition (VPT), associated to a minimum of the Poisson's ratio $\nu$. Recent numerical investigations uncovered the occurrence of a Hyper-Auxetic Transition…

Soft Condensed Matter · Physics 2024-07-31 Andrea Ninarello , Emanuela Zaccarelli

This is an integrated experimental and theoretical study of the dynamics and rheology of self-crosslinked, slightly charged, temperature responsive soft Poly(N-isopropylacrylamide) (pNIPAM) microgels over a wide range of concentration and…

Soft Condensed Matter · Physics 2021-03-04 Gaurav Chaudhary , Ashesh Ghosh , Jin Gu Kang , Paul V. Braun , Randy H. Ewoldt , Kenneth S. Schweizer

Microgels are often discussed as well-suited model system for soft colloids. In contrast to rigid spheres, the microgel volume and, coupled to this, the volume fraction in dispersion can be manipulated by external stimuli. This behavior is…

The phase behavior of poly (N-isopropylacrylamide) nanoparticles dispersed in aqueous medium is investigated as a function of temperature using static and dynamic light scattering techniques. The diameter, d of the particles, as determined…

Soft Condensed Matter · Physics 2008-06-11 J. Brijitta , B. V. R. Tata , T. Kaliyappan

We synthesize thermoresponsive poly(N-isopropylacrylamide) (PNIPAM) colloidal microgel particles of different stiffnesses by controlling the concentration of crosslinker in a one-pot synthesis method. We employ oscillatory rheology and…

Soft Condensed Matter · Physics 2024-02-12 Chandeshwar Misra , Sanjay Kumar Behera , Sonali Vasant Kawale , Ranjini Bandyopadhyay

Poly(N-isopropylacrylamide), PNIPAM, is a widely studied polymer, which serves as a key constituent of nanostructured soft materials with responsive properties. Upon increasing temperature the PNIPAM polymer chain undergoes a reversible…

Soft Condensed Matter · Physics 2019-10-22 Letizia Tavagnacco , Emanuela Zaccarelli , Ester Chiessi
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