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Transmission rates in epidemic outbreaks may vary over time depending on the societal response. Non-pharmacological mitigation strategies such as social distancing and the adoption of protective equipment aim precisely at reducing…

Populations and Evolution · Quantitative Biology 2020-12-24 Elisa Franco

The dynamics of epidemics depend on how people's behavior changes during an outbreak. At the beginning of the epidemic, people do not know about the virus, then, after the outbreak of epidemics and alarm, they begin to comply with the…

Physics and Society · Physics 2021-11-29 I. A. Kastalskiy , E. V. Pankratova , E. M. Mirkes , V. B. Kazantsev , A. N. Gorban

Non-pharmaceutical interventions (NPIs) are effective measures to contain a pandemic. Yet, such control measures commonly have a negative effect on the economy. Here, we propose a macro-level approach to support resolving this…

Neural and Evolutionary Computing · Computer Science 2021-02-25 Rohit Salgotra , Thomas Seidelmann , Dominik Fischer , Sanaz Mostaghim , Amiram Moshaiov

Within the likes of any highly contagious and unpredictable disease, lies a predictable and attainable growth rate that researchers can find in order to make logistical conclusions about that particular disease and its affected regions'…

Applications · Statistics 2024-02-05 Julian Bennett , Lauren Eriksen , Xingjie Helen Li

We adapt a SEIRD differential model with asymptomatic population and Covid deaths, which we call SEAIRD, to simulate the evolution of COVID-19, and add a control function affecting both the diffusion of the virus and GDP, featuring all…

Physics and Society · Physics 2020-06-02 Andrea Aspri , Elena Beretta , Alberto Gandolfi , Etienne Wasmer

We consider the $SEIRS$ epidemiology model with such features of the COVID-19 outbreak as: abundance of unidentified infected individuals, limited time of immunity and a possibility of vaccination. Within a compartmental realization of this…

Populations and Evolution · Quantitative Biology 2021-12-07 Jaroslav Ilnytskyi , Taras Patsahan

We consider an SEIR epidemic model on a network also allowing random contacts, where recovered individuals could either recover naturally or be diagnosed. Upon diagnosis, manual contact tracing is triggered such that each infected network…

Physics and Society · Physics 2024-06-06 Dongni Zhang , Tom Britton

This paper is concerned with the well-posedness and optimal control problem of a reaction-diffusion system for an epidemic Susceptible-Infected-Recovered-Susceptible (SIRS) mathematical model in which the dynamics develops in a spatially…

Optimization and Control · Mathematics 2023-04-24 Pierluigi Colli , Gianni Gilardi , Gabriela Marinoschi , Elisabetta Rocca

The paper addresses the question of lives versus livelihood in an SIRD model augmented with a macroeconomic structure. The constraints on the availability of health facilities - both infrastructure and health workers determine the…

Dynamical Systems · Mathematics 2021-09-07 Gopal K. Basak , Chandramauli Chakraborty , Pranab Kumar Das

A model of reactive social distancing in epidemics is proposed, in which the infection rate changes with the number infected. The final-size equation for the total number that the epidemic will infect can be derived analytically, as can the…

Populations and Evolution · Quantitative Biology 2020-03-19 Rose Baker

Research in epidemiology often focusses on designing interventions that result in the number of infected individuals asymptotically approaching zero, without considering that this number may peak at high values during transients. Recent…

Optimization and Control · Mathematics 2020-03-24 Willem Esterhuizen , Tim Aschenbruck , Jean Lévine , Stefan Streif

A Markovian SIR (Susceptible-Infectious-Recovered) model is considered for the spread of an epidemic on a configuration model network, in which susceptible individuals may take preventive measures by dropping edges to infectious neighbours.…

Probability · Mathematics 2019-01-23 Frank Ball , Tom Britton , Ka Yin Leung , David Sirl

Modeling epidemic dynamics plays an important role in studying how diseases spread, predicting their future course, and designing strategies to control them. In this letter, we introduce a model of SIR (susceptible-infected-removed) type…

Populations and Evolution · Quantitative Biology 2013-12-17 Li Chen , Fakhteh Ghanbarnejad , Weiran Cai , Peter Grassberger

Background: Restrictive mass quarantine or lockdown has been implemented as the most important controlling measure to fight against COVID-19. Many countries have enforced 2 - 4 weeks' lockdown and are extending the period depending on their…

Populations and Evolution · Quantitative Biology 2020-10-28 Sarmistha Das , Pramit Ghosh , Bandana Sen , Indranil Mukhopadhyay

In this paper, we study the dynamics of epidemic processes taking place in adaptive networks of arbitrary topology. We focus our study on the adaptive susceptible-infected-susceptible (ASIS) model, where healthy individuals are allowed to…

Social and Information Networks · Computer Science 2016-06-29 Masaki Ogura , Victor M. Preciado

The main aim of the work is to present a general class of two time scales discrete-time epidemic models. In the proposed framework the disease dynamics is considered to act on a slower time scale than a second different process that could…

Dynamical Systems · Mathematics 2024-02-07 Luis Sanz-Lorenzo , Rafael Bravo de la Parra

In the absence of any available vaccines or drugs, prevention of the spread of Coronavirus Disease 2019 (COVID-19) pandemic is being achieved by putting many mitigation measures in place. It is indispensable to have robust and reliable ways…

Populations and Evolution · Quantitative Biology 2020-04-17 Gaurav Goswami , Jayanti Prasad , Mansi Dhuria

The Susceptible-Infectious-Recovered (SIR) equations and their extensions comprise a commonly utilized set of models for understanding and predicting the course of an epidemic. In practice, it is of substantial interest to estimate the…

Applications · Statistics 2025-05-07 Omar Melikechi , Alexander L. Young , Tao Tang , Trevor Bowman , David Dunson , James Johndrow

We study the impact of model parameter uncertainty on optimally mitigating the spread of epidemics. We capture the epidemic spreading process using a susceptible-infected-removed (SIR) epidemic model and consider testing for isolation as…

Systems and Control · Electrical Eng. & Systems 2022-09-07 Baike She , Shreyas Sundaram , Philip E. Paré

Optimal control problems reflecting the finding of effective quarantine strategies are considered for two control SEIR~type models describing the spread of the COVID-19 virus in the human population. The properties of the corresponding…

Optimization and Control · Mathematics 2020-11-30 Ellina Grigorieva , Evgenii Khailov , Andrei Korobeinikov