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Understanding and predicting microstructure evolution is fundamental to materials science, as it governs the resulting properties and performance of materials. Traditional simulation methods, such as phase-field models, offer high-fidelity…
Depression is a major global public health challenge and its early identification is crucial. Social media data provides a new perspective for depression detection, but existing methods face limitations such as insufficient accuracy,…
Autism Spectrum Disorders are associated with atypical movements, of which stereotypical motor movements (SMMs) interfere with learning and social interaction. The automatic SMM detection using inertial measurement units (IMU) remains…
This paper introduces a simple efficient learning algorithms for general sequential decision making. The algorithm combines Optimism for exploration with Maximum Likelihood Estimation for model estimation, which is thus named OMLE. We prove…
Interpretability is a critical factor in applying complex deep learning models to advance the understanding of brain disorders in neuroimaging studies. To interpret the decision process of a trained classifier, existing techniques typically…
Brain disorders in the early and late life of humans potentially share pathological alterations in brain functions. However, the key evidence from neuroimaging data for pathological commonness remains unrevealed. To explore this hypothesis,…
Clinicians usually combine information from multiple sources to achieve the most accurate diagnosis, and this has sparked increasing interest in leveraging multimodal deep learning for diagnosis. However, in real clinical scenarios, due to…
Deep models, e.g., CNNs and Vision Transformers, have achieved impressive achievements in many vision tasks in the closed world. However, novel classes emerge from time to time in our ever-changing world, requiring a learning system to…
Autistic Spectrum Disorder (ASD) is a neurological disease characterized by difficulties with social interaction, communication, and repetitive activities. While its primary origin lies in genetics, early detection is crucial, and…
While Large Language Models (LLMs) are emerging as a promising direction in computational pathology, the substantial computational cost of giga-pixel Whole Slide Images (WSIs) necessitates the use of Multi-Instance Learning (MIL) to enable…
Multiple instance learning (MIL) has become the leading approach for extracting discriminative features from whole slide images (WSIs) in computational pathology. Attention-based MIL methods can identify key patches but tend to overlook…
Single-cell datasets often lack individual cell labels, making it challenging to identify cells associated with disease. To address this, we introduce Mixture Modeling for Multiple Instance Learning (MMIL), an expectation maximization…
Schizophrenia is a debilitating, chronic mental disorder that significantly impacts an individual's cognitive abilities, behavior, and social interactions. It is characterized by subtle morphological changes in the brain, particularly in…
Large language models (LLMs) have demonstrated that large-scale pretraining enables systems to adapt rapidly to new problems with little supervision in the language domain. This success, however, has not translated as effectively to the…
Automatic depression detection provides cues for early clinical intervention by clinicians. Clinical interviews for depression detection involve dialogues centered around multiple themes. Existing studies primarily design end-to-end neural…
Alzheimer's disease is a neurodegenerative condition that accelerates cognitive decline relative to normal aging. It is of critical scientific importance to gain a better understanding of early disease mechanisms in the brain to facilitate…
In statistical learning, many problem formulations have been proposed so far, such as multi-class learning, complementarily labeled learning, multi-label learning, multi-task learning, which provide theoretical models for various real-world…
Recently, In-context Learning (ICL) has become a significant inference paradigm in Large Multimodal Models (LMMs), utilizing a few in-context demonstrations (ICDs) to prompt LMMs for new tasks. However, the synergistic effects in multimodal…
Recent advancements in deep learning have shifted the development of brain imaging analysis. However, several challenges remain, such as heterogeneity, individual variations, and the contradiction between the high dimensionality and small…
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition whose rising prevalence places increasing demands on a lengthy diagnostic process. Machine learning (ML) has shown promise in automating ASD diagnosis, but most…