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Video-rate super-resolution imaging through biological tissue can visualize and track biomolecule interplays and transportations inside cellular organisms. Structured illumination microscopy allows for wide-field super resolution…

Scanning Electron Microscopy (SEM) is pivotal in revealing intricate micro- and nanoscale features across various research fields. However, obtaining high-resolution SEM images presents challenges, including prolonged scanning durations and…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Tom Reclik , Setareh Medghalchi , Philipp Schumacher , Maximilian Wollenweber , Talal Al-Samman , Sandra Korte-Kerzel , Ulrich Kerzel

By integrating a phase-only Spatial Light Modulator (SLM) into the illumination arm of a cylindrical-lens-based Selective Plane Illumination Microscope (SPIM), we have created a versatile system able to deliver high quality images by…

Biological Physics · Physics 2018-08-10 Chiara Garbellotto , Jonathan M. Taylor

In recent years, image-scanning microscopy (ISM, also termed pixel-reassignment microscopy) has emerged as a technique that improves the resolution and signal-to-noise compared to confocal and widefield microscopy by employing a detector…

Optics · Physics 2023-04-19 Tal I. Sommer , Gil Weinberg , Ori Katz

The iterative refinement method (IRM) has been very successfully applied in many different fields for examples the modern quantum chemical calculation and CT image reconstruction. It is proved that the refinement method can create an exact…

Medical Physics · Physics 2015-12-23 Kang Yang , Kevin Yang , Xintie Yang , Shuang-Ren Zhao

Research and medicine rely on non-invasive optical techniques to image living tissue with high resolution in space and time. But so far a single data acquisition could not provide entirely diffraction-limited tomographic volumes of rapidly…

Super-resolution fluorescence microscopy is an important tool in biomedical research for its ability to discern features smaller than the diffraction limit. However, due to its difficult implementation and high cost, the universal…

Idier et al. [IEEE Trans. Comput. Imaging 4(1), 2018] propose a method which achieves superresolution in the microscopy setting by leveraging random speckle illumination and knowledge about statistical second order moments for the…

Signal Processing · Electrical Eng. & Systems 2022-02-02 Osman Asif Malik , Venkatalakshmi Vyjayanthi Narumanchi , Stephen Becker , Todd W. Murray

While electron microscopy offers crucial atomic-resolution insights into structure-property relationships, radiation damage severely limits its use on beam-sensitive materials like proteins and 2D materials. To overcome this challenge, we…

Computer Vision and Pattern Recognition · Computer Science 2025-07-18 Zifei Wang , Zian Mao , Xiaoya He , Xi Huang , Haoran Zhang , Chun Cheng , Shufen Chu , Tingzheng Hou , Xiaoqin Zeng , Yujun Xie

We demonstrate structured illumination super-resolution imaging in the Terahertz (THz) frequency band using the Virtually Structured Detection (VSD) method. Leveraging our previously reported high-speed, high-sensitivity atomic-based THz…

We demonstrate the combination of a hemispherical solid immersion lens with a micro-photoluminescence setup. Two advantages introduced by the SIL, an improved resolution of 0.4 times the wavelength in vacuum and a 5 times enhancement of the…

Optics · Physics 2009-11-07 S. Moehl , Hui Zhao , B. Dal Don , S. Wachter , H. Kalt

Regularization is essential in deep learning to enhance generalization and mitigate overfitting. However, conventional techniques often rely on heuristics, making them less reliable or effective across diverse settings. We propose Self…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Xiuding Cai , Yaoyao Zhu , Linjie Fu , Dong Miao , Yu Yao

The revolutionary technology of \emph{Stacked Intelligent Metasurfaces (SIM)} has been recently shown to be capable of carrying out advanced signal processing directly in the native electromagnetic (EM) wave domain. An SIM is fabricated by…

Information Theory · Computer Science 2023-05-16 Jiancheng An , Chao Xu , Derrick Wing Kwan Ng , George C. Alexandropoulos , Chongwen Huang , Chau Yuen , Lajos Hanzo

Circulatory system abnormalities might be an indicator of diseases or tissue damage. Early detection of vascular abnormalities might have an important role during treatment and also raise the patient's awarenes. Current detection methods…

Computer Vision and Pattern Recognition · Computer Science 2023-09-07 Ayse Altay , Abdurrahman Gumus

We consider the problem of active 3D imaging using single-shot structured light systems, which are widely employed in commercial 3D sensing devices such as Apple Face ID and Intel RealSense. Traditional structured light methods typically…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Jiaheng Li , Qiyu Dai , Lihan Li , Praneeth Chakravarthula , He Sun , Baoquan Chen , Wenzheng Chen

Allying high-resolution with a large field-of-view (FOV) is of great importance in the fields of biology and medicine, but particularly challenging when imaging non-flat living samples such as the human retina. Indeed, high-resolution is…

For collecting high-quality high-resolution (HR) MR image, we propose a novel image reconstruction network named IREM, which is trained on multiple low-resolution (LR) MR images and achieve an arbitrary up-sampling rate for HR image…

Image and Video Processing · Electrical Eng. & Systems 2021-06-30 Qing Wu , Yuwei Li , Lan Xu , Ruiming Feng , Hongjiang Wei , Qing Yang , Boliang Yu , Xiaozhao Liu , Jingyi Yu , Yuyao Zhang

This study proposes an algorithm based on a notch filter camera array system for simultaneous super-resolution imaging and spectral reconstruction, enhancing the spatial resolution and multispectral imaging capabilities of targets. In this…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Peng Lin , Xuesong Wang , Yating Chen , Xianyu Wu , Feng Huang , Shouqian Chen

Microscopy is routinely used to image biological structures of interest. Due to imaging constraints, acquired images, also called as micrographs, are typically low-SNR and contain noise. Over the last few years, regression-based tasks like…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Ashesh Ashesh , Joran Deschamps , Florian Jug

Despite super-resolution fluorescence blinking microscopes break the diffraction limit, the intense phototoxic illumination and long-term image sequences thus far still pose to major challenges in visualizing live-organisms. Here, we…