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Background: Non-linear alterations in brain network connectivity may represent early neural signatures of Alzheimer's disease (AD) pathology in cognitively normal older adults. Understanding these changes and their cognitive relevance may…

Neurons and Cognition · Quantitative Biology 2026-04-22 Junjie Wu , Benjamin B Risk , Taylor A James , Nicholas Seyfried , David W Loring , Felicia C Goldstein , Allan I Levey , James J Lah , Deqiang Qiu

Analysis of brain connectivity is important for understanding how information is processed by the brain. We propose a novel Bayesian vector autoregression (VAR) hierarchical model for analyzing brain connectivity in a resting-state fMRI…

Applications · Statistics 2021-12-09 Bertil Wegmann , Anders Lundquist , Anders Eklund , Mattias Villani

Autism spectrum disorder (ASD) is one of the major developmental disorders affecting children. Recently, it has been hypothesized that ASD is associated with atypical brain connectivities. A substantial body of researches use Pearson's…

Neurons and Cognition · Quantitative Biology 2019-03-06 Biwei Huang , Kun Zhang , Ruben Sanchez-Romero , Joseph Ramsey , Madelyn Glymour , Clark Glymour

Resting-state brain functional connectivity quantifies the synchrony between activity patterns of different brain regions. In functional magnetic resonance imaging (fMRI), each region comprises a set of spatially contiguous voxels at which…

Methodology · Statistics 2025-11-07 Ruobin Liu , Chao Zhang , Chau Tran , Sophie Achard , Wendy Meiring , Alexander Petersen

The integration and transmission of information in the brain are dependent on the interplay between structural and dynamical properties. Implicit in any pursuit aimed at understanding neural dynamics from appropriate sets of mathematically…

Neurons and Cognition · Quantitative Biology 2020-06-30 Joshua M. Roldan , Sebastian Pardo G. , Vivek Kurien George , Gabriel A. Silva

Contemporary neuroimaging methods can shed light on the basis of human neural and cognitive specializations, with important implications for neuroscience and medicine. Different MRI acquisitions provide different brain networks at the…

Neurons and Cognition · Quantitative Biology 2016-02-23 C. Alonso-Montes , I. Diez , L. Remaki , I. Escudero , B. Mateos , Y. Rosseel , D. Marinazzo , S. Stramaglia , J. Cortes

The human brain has long inspired the pursuit of artificial intelligence (AI). Recently, neuroimaging studies provide compelling evidence of alignment between the computational representation of artificial neural networks (ANNs) and the…

Neurons and Cognition · Quantitative Biology 2024-11-01 Haiyang Sun , Lin Zhao , Zihao Wu , Xiaohui Gao , Yutao Hu , Mengfei Zuo , Wei Zhang , Junwei Han , Tianming Liu , Xintao Hu

Understanding associations between paired high-dimensional longitudinal datasets is a fundamental yet challenging problem that arises across scientific domains, including longitudinal multi-omic studies. The difficulty stems from the…

Methodology · Statistics 2026-01-21 Jianbin Tan , Pixu Shi

Neuroimaging-driven prediction of brain age, defined as the predicted biological age of a subject using only brain imaging data, is an exciting avenue of research. In this work we seek to build models of brain age based on functional…

In the study of biological networks, one of the major challenges is to understand the relationships between network structure and dynamics. In this paper, we model in vitro cortical neuronal cultures as stochastic dynamical systems and…

Neurons and Cognition · Quantitative Biology 2022-05-04 Chumin Sun , K. C. Lin , C. Y. Yeung , Emily S. C. Ching , Yu-Ting Huang , Pik-Yin Lai , C. K. Chan

We present a computational framework for analysis and visualization of non-linear functional connectivity in the human brain from resting state functional MRI (fMRI) data for purposes of recovering the underlying network community structure…

Neural and Evolutionary Computing · Computer Science 2014-07-16 Axel Wismüller , Xixi Wang , Adora M. DSouza , Mahesh B. Nagarajan

Simultaneous estimates of the activity in the left and right auditory cortex of five normal human subjects were extracted from Multichannel Magnetoencephalography recordings. Left, right and binaural stimulation were used, in separate runs,…

Biological Physics · Physics 2009-10-31 J. Kwapien , S. Drozdz , L. C. Liu , A. A. Ioannides

Measures of linear dependence (coherence) and nonlinear dependence (phase synchronization) between any number of multivariate time series are defined. The measures are expressed as the sum of lagged dependence and instantaneous dependence.…

Methodology · Statistics 2007-11-12 Roberto D. Pascual-Marqui

Neural network models in neuroscience allow one to study how the connections between neurons shape the activity of neural circuits in the brain. In this chapter, we study Combinatorial Threshold-Linear Networks (CTLNs) in order to…

Neurons and Cognition · Quantitative Biology 2018-04-05 Katherine Morrison , Carina Curto

Anatomic connections between brain areas affect information flow between neuronal circuits and the synchronization of neuronal activity. However, such structural connectivity does not coincide with effective connectivity, related to the…

Neurons and Cognition · Quantitative Biology 2015-06-03 Demian Battaglia , Annette Witt , Fred Wolf , Theo Geisel

A central challenge in the computational modeling of neural dynamics is the trade-off between accuracy and simplicity. At the level of individual neurons, nonlinear dynamics are both experimentally established and essential for neuronal…

We advance our approach of analyzing the dynamics of interacting complex systems with the nonlinear dynamics of interacting nonlinear elements. We replace the widely used lattice-like connection topology of cellular neural networks (CNN) by…

Neurons and Cognition · Quantitative Biology 2016-10-10 Henning Dickten , Christian E. Elger , Klaus Lehnertz

Executive functioning is a cognitive process that enables humans to plan, organize, and regulate their behavior in a goal-directed manner. Understanding and classifying the changes in executive functioning after longitudinal interventions…

Human-Computer Interaction · Computer Science 2024-02-01 Akash K Rao , Vishnu K Menon , Shashank Uttrani , Ayushman Dixit , Dipanshu Verma , Varun Dutt

Understanding how the brain represents visual information is a fundamental challenge in neuroscience and artificial intelligence. While AI-driven decoding of neural data has provided insights into the human visual system, integrating…

Neural and Evolutionary Computing · Computer Science 2025-10-07 Dongyang Li , Haoyang Qin , Mingyang Wu , Chen Wei , Quanying Liu

Autism spectrum disorder (ASD) is regarded as a brain disease with globally disrupted neuronal networks. Even though fMRI studies have revealed abnormal functional connectivity in ASD, they have not reached a consensus of the disrupted…

Computer Vision and Pattern Recognition · Computer Science 2017-07-26 Hongyoon Choi