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Detection of rare variants by resequencing is important for the identification of individuals carrying disease variants. Rapid sequencing by new technologies enables low-cost resequencing of target regions, although it is still prohibitive…

Genomics · Quantitative Biology 2009-09-03 Noam Shental , Amnon Amir , Or Zuk

The coronavirus disease 2019 (COVID-19) pandemic has spread rapidly across the world, leading to enormous amounts of human death and economic loss. Until definitive preventive or curative measures are developed, policies regarding testing,…

With the extensive use of digital devices, online experimental platforms are commonly used to conduct experiments to collect data for evaluating different variations of products, algorithms, and interface designs, a.k.a., A/B tests. In…

Methodology · Statistics 2024-07-09 Qiong Zhang , Lulu Kang , Xinwei Deng

Group testing enables to identify infected individuals in a population using a smaller number of tests than individual testing. To achieve this, group testing algorithms commonly assume knowledge of the number of infected individuals;…

Information Theory · Computer Science 2023-05-16 Chaorui Yao , Pavlos Nikolopoulos , Christina Fragouli

We consider some computationally efficient and provably correct algorithms with near-optimal sample-complexity for the problem of noisy non-adaptive group testing. Group testing involves grouping arbitrary subsets of items into pools. Each…

Information Theory · Computer Science 2016-11-18 Chun Lam Chan , Sidharth Jaggi , Venkatesh Saligrama , Samar Agnihotri

In epidemic or pandemic situations, resources for testing the infection status of individuals may be scarce. Although group testing can help to significantly increase testing capabilities, the (repeated) testing of entire populations can…

Populations and Evolution · Quantitative Biology 2021-10-29 Günther Koliander , Georg Pichler

The rapid finding of effective therapeutics requires the efficient use of available resources in clinical trials. The use of covariate adjustment can yield statistical estimates with improved precision, resulting in a reduction in the…

Methodology · Statistics 2021-09-10 Nicholas Williams , Michael Rosenblum , Iván Díaz

The fundamental task of group testing is to recover a small distinguished subset of items from a large population while efficiently reducing the total number of tests (measurements). The key contribution of this paper is in adopting a new…

Information Theory · Computer Science 2015-03-13 George Kamal Atia , Venkatesh Saligrama

I present a frequentist method for quantifying uncertainty when correcting correlations for attenuation due to measurement error. The method is conservative but has far better coverage properties than the methods currently used when sample…

Methodology · Statistics 2019-11-06 Jonas Moss

Benchmarking the performance of quantum error correction codes in physical systems is crucial for achieving fault-tolerant quantum computing. Current methodologies, such as (shadow) tomography or direct fidelity estimation, fall short in…

Quantum Physics · Physics 2024-10-17 Junjie Chen , Pei Zeng , Qi Zhao , Xiongfeng Ma , You Zhou

We introduce KodCode, a synthetic dataset that addresses the persistent challenge of acquiring high-quality, verifiable training data across diverse difficulties and domains for training Large Language Models for coding. Existing…

Machine Learning · Computer Science 2025-07-15 Zhangchen Xu , Yang Liu , Yueqin Yin , Mingyuan Zhou , Radha Poovendran

Accurate estimation of treatment effects in online A/B testing is challenging with zero-inflated and skewed metrics. Traditional tests, like Welch's t-test, often lack sensitivity with heavy-tailed data due to their reliance on means, as…

Methodology · Statistics 2025-10-07 Kevin Charette , Tristan Boudreault

In this paper, we study the pooled data problem of identifying the labels associated with a large collection of items, based on a sequence of pooled tests revealing the counts of each label within the pool. In the noiseless setting, we…

Machine Learning · Statistics 2017-10-19 Jonathan Scarlett , Volkan Cevher

The main purpose of this study is to develop a pipeline for COVID-19 detection from a big and challenging database of Computed Tomography (CT) images. The proposed pipeline includes a segmentation part, a lung extraction part, and a…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Kenan Morani

Text error correction aims to correct the errors in text sequences such as those typed by humans or generated by speech recognition models. Previous error correction methods usually take the source (incorrect) sentence as encoder input and…

Computation and Language · Computer Science 2022-11-28 Kai Shen , Yichong Leng , Xu Tan , Siliang Tang , Yuan Zhang , Wenjie Liu , Edward Lin

Cough audio signal classification is a potentially useful tool in screening for respiratory disorders, such as COVID-19. Since it is dangerous to collect data from patients with such contagious diseases, many research teams have turned to…

Sound · Computer Science 2023-08-22 Lara Orlandic , Tomas Teijeiro , David Atienza

In this paper, we propose a general method for testing composite hypotheses. Our idea is to use confidence limits to define stopping and decision rules. The requirements of operating characteristic function can be satisfied by adjusting the…

Statistics Theory · Mathematics 2012-02-10 Xinjia Chen

In early clinical test evaluations the potential benefits of the introduction of a new technology into the healthcare system are assessed in the challenging situation of limited available empirical data. The aim of these evaluations is to…

Applications · Statistics 2020-05-21 Sara Graziadio , Kevin J. Wilson

Identifying subgroups of patients with an enhanced response to a new treatment has become an area of increased interest in the last few years. When there is knowledge about possible subpopulations with an enhanced treatment effect before…

Methodology · Statistics 2018-11-27 Marius Thomas , Björn Bornkamp , Martin Posch , Franz König

In recent years, there is a growing body of causal inference literature focusing on covariate balancing methods. These methods eliminate observed confounding by equalizing covariate moments between the treated and control groups. The…

Methodology · Statistics 2024-06-14 Xialing Wen , Ying Yan