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During the COVID-19 pandemic, many institutions such as universities and workplaces implemented testing regimens with every member of some population tested longitudinally, and those testing positive isolated for some time. Although the…

Methodology · Statistics 2023-04-19 Patrick M. Schnell , Matthew Wascher , Grzegorz A. Rempala

CoVID-19 is currently one of the biggest threats to mankind. To date, it is the reason for infections of over 35 lakhs and the death of over 2 lakh human beings. We propose a procedure to detect CoVID-19 affected localities using a sewage…

Other Quantitative Biology · Quantitative Biology 2020-05-18 Ritam Guha , Anik Sengupta , Ankan Dutta

Group testing can help maintain a widespread testing program using fewer resources amid a pandemic. In a group testing setup, we are given n samples, one per individual. Each individual is either infected or uninfected. These samples are…

Signal Processing · Electrical Eng. & Systems 2023-07-19 Shu-Jie Cao , Ritesh Goenka , Chau-Wai Wong , Ajit Rajwade , Dror Baron

We study the problem of group testing with non-identical, independent priors. So far, the pooling strategies that have been proposed in the literature take the following approach: a hand-crafted test design along with a decoding strategy is…

Information Theory · Computer Science 2022-01-31 Sundara Rajan Srinivasavaradhan , Pavlos Nikolopoulos , Christina Fragouli , Suhas Diggavi

Large-scale testing is crucial in pandemic containment, but resources are often prohibitively constrained. We study the optimal application of pooled testing for populations that are heterogeneous with respect to an individual's infection…

Computer Science and Game Theory · Computer Science 2023-09-22 Simon Finster , Michelle González Amador , Edwin Lock , Francisco Marmolejo-Cossío , Evi Micha , Ariel D. Procaccia

To strengthen inferences meta analyses are commonly used to summarize information from a set of independent studies. In some cases, though, the data may not satisfy the assumptions underlying the meta analysis. Using three Bayesian methods…

Applications · Statistics 2022-04-07 Dexter Cahoy , Joseph Sedransk

It is quite common in modern research, for a researcher to test many hypotheses. The statistical (frequentist) hypothesis testing framework, does not scale with the number of hypotheses in the sense that naively performing many hypothesis…

Methodology · Statistics 2013-06-26 Jonathan Rosenblatt

Group testing allows saving chemical reagents, analysis time, and costs, by testing pools of samples instead of individual samples. We introduce a class of group testing protocols with small dilution, suited to operate even at high…

Physics and Society · Physics 2022-03-09 Marco Chiani , Gianluigi Liva , Enrico Paolini

Since the onset of the COVID-19 pandemic in 2020, millions of people have succumbed to this deadly virus. Many attempts have been made to devise an automated method of testing that could detect the virus. Various researchers around the…

Image and Video Processing · Electrical Eng. & Systems 2021-11-11 Samyak Prajapati , Japman Singh Monga , Shaanya Singh , Amrit Raj , Yuvraj Singh Champawat , Chandra Prakash

Long-term care facilities have been widely affected by the COVID-19 pandemic. Retirement homes are particularly vulnerable due to the higher mortality risk of infected elderly individuals. Once an outbreak occurs, suppressing the spread of…

Optimization and Control · Mathematics 2022-04-06 Mansoor Davoodi , Ana Batista , Abhishek Senapati , Weronika Schlechte-Welnicz , Birgit Wagner , Justin M. Calabrese

The original problem of group testing consists in the identification of defective items in a collection, by applying tests on groups of items that detect the presence of at least one defective item in the group. The aim is then to identify…

Applications · Statistics 2021-06-10 Emilien Joly , Bastien Mallein

In order to overcome the limitations imposed by DNA barcoding when multiplexing a large number of samples in the current generation of high-throughput sequencing instruments, we have recently proposed a new protocol that leverages advances…

Quantitative Methods · Quantitative Biology 2013-08-02 Denisa Duma , Mary Wootters , Anna C. Gilbert , Hung Q. Ngo , Atri Rudra , Matthew Alpert , Timothy J. Close , Gianfranco Ciardo , Stefano Lonardi

Coronavirus case-count data has influenced government policies and drives most epidemiological forecasts. Limited testing is cited as the key driver behind minimal information on the COVID-19 pandemic. While expanded testing is laudable,…

Methodology · Statistics 2022-09-22 Walter Dempsey

We consider the optimal strategy for laboratory testing of biological samples when we wish to know the results for each sample rather than the average prevalence of positive samples. If the proportion of positive samples is low considerable…

Quantitative Methods · Quantitative Biology 2010-07-29 Brian G. Williams

The cataclysmic contagion based calamity -- Covid-19 has shown us a clear need for a comprehensive community based strategy that overcomes the sheer complexity of controlling it and the caveats of current methods. In this regard, as seen in…

Physics and Society · Physics 2021-09-17 Surya Dheeshjith , Inavamsi Enaganti , Bud Mishra

The development of fast and accurate screening tools, which could facilitate testing and prevent more costly clinical tests, is key to the current pandemic of COVID-19. In this context, some initial work shows promise in detecting…

Gathering observational data for medical decision-making often involves uncertainties arising from both type I (false positive)and type II (false negative) errors. In this work, we develop a statistical model to study how medical…

Applications · Statistics 2025-10-21 Lucas Böttcher , Maria R. D'Orsogna , Tom Chou

The gold standard for COVID-19 is RT-PCR, testing facilities for which are limited and not always optimally distributed. Test results are delayed, which impacts treatment. Expert radiologists, one of whom is a co-author, are able to…

Computer Vision and Pattern Recognition · Computer Science 2021-02-17 Kartikeya Badola , Sameer Ambekar , Himanshu Pant , Sumit Soman , Anuradha Sural , Rajiv Narang , Suresh Chandra , Jayadeva

Codeword stabilized (CWS) codes are, in general, non-additive quantum codes that can correct errors by an exhaustive search of different error patterns, similar to the way that we decode classical non-linear codes. For an n-qubit quantum…

Quantum Physics · Physics 2010-05-28 Yunfan Li , Ilya Dumer , Markus Grassl , Leonid P. Pryadko

Controlling the COVID-19 pandemic is an urgent global challenge. The rapid geographic spread of SARS-CoV-2 directly reflects the social structure. Before effective vaccines and treatments are widely available, we have to rely on…

Physics and Society · Physics 2021-08-11 Karina I Mazzitello , Yi Jiang , Constancio M Arizmendi