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A cluster tree provides a highly-interpretable summary of a density function by representing the hierarchy of its high-density clusters. It is estimated using the empirical tree, which is the cluster tree constructed from a density…

Statistics Theory · Mathematics 2017-02-14 Jisu Kim , Yen-Chi Chen , Sivaraman Balakrishnan , Alessandro Rinaldo , Larry Wasserman

Galled trees are studied as a recombination model in population genetics. This class of phylogenetic networks is generalized into tree-child, galled and reticulation-visible network classes by relaxing a structural condition imposed on…

Populations and Evolution · Quantitative Biology 2020-02-28 Gabriel Cardona , Louxin Zhang

Bayesian inference is a popular and widely-used approach to infer phylogenies (evolutionary trees). However, despite decades of widespread application, it remains difficult to judge how well a given Bayesian Markov chain Monte Carlo (MCMC)…

Methodology · Statistics 2022-09-07 Andrew F. Magee , Michael D. Karcher , Frederick A. Matsen , Vladimir N. Minin

Terraces are potentially large sets of trees with precisely the same likelihood or parsimony score, which can be induced by missing sequences in partitioned multi-locus phylogenetic data matrices. The set of trees on a terrace can be…

Populations and Evolution · Quantitative Biology 2014-10-30 Michael J Sanderson , Michelle M. McMahon , Alexandros Stamatakis , Derrick J. Zwickl , Mike Steel

In this article the results of Waddell and Azad (2009) are extended. In particular, the geometric percentage mean standard deviation measure of the fit of distances to a phylogenetic tree is adjusted for the number of parameters fitted to…

Populations and Evolution · Quantitative Biology 2011-01-04 Peter J. Waddell , Ariful Azad , Ishita Khan

Staged trees are a recently-developed, powerful family of probabilistic graphical models. An equivalence class of staged trees has now been characterised, and two fundamental statistical operators have been defined to traverse the…

Methodology · Statistics 2023-01-18 Conor Hughes , Peter Strong , Aditi Shenvi

Phylogenetics is now fundamental in life sciences, providing insights into the earliest branches of life and the origins and spread of epidemics. However, finding suitable phylogenies from the vast space of possible trees remains…

Populations and Evolution · Quantitative Biology 2024-01-24 Matthew J Penn , Neil Scheidwasser , Joseph Penn , Christl A Donnelly , David A Duchêne , Samir Bhatt

Billey et al. [arXiv:1507.04976] have recently discovered a surprisingly simple formula for the number $a_n(\sigma)$ of leaf-labelled rooted non-embedded binary trees (also known as phylogenetic trees) with $n\geq 1$ leaves, fixed (for the…

Combinatorics · Mathematics 2016-03-08 Éric Fusy

Rooted bifurcating trees are mathematical objects used to model evolutionary relationships and arise naturally in both coalescent theory and phylogenetics. Recent numerical representations of tree topologies, known as F-matrices, allow for…

Invariants for complicated objects such as those arising in phylogenetics, whether they are invariants as matrices, polynomials, or other mathematical structures, are important tools for distinguishing and working with such objects. In this…

Populations and Evolution · Quantitative Biology 2022-04-06 Joan Carles Pons , Tomás M. Coronado , Michael Hendriksen , Andrew Francis

The inference of the evolutionary history of a collection of organisms is a problem of fundamental importance in evolutionary biology. The abundance of DNA sequence data arising from genome sequencing projects has led to significant…

Populations and Evolution · Quantitative Biology 2015-07-07 Julia Chifman , Laura Kubatko

Estimating the effective sample size (ESS) is fundamental in Bayesian phylogenetic inference to properly account for autocorrelation in MCMC samples. While methods for continuous parameters are well established, the discrete and…

Populations and Evolution · Quantitative Biology 2026-03-05 Jonathan Klawitter , Lars Berling , Jordan Douglas , Dong Xie , Alexei J. Drummond

This paper builds up on T. Martinez-Coronado, A. Mir, F. Rossello and G. Valiente's work "A balance index for phylogenetic trees based on quartets", introducing a new balance index for trees. We show here that this balance index, in the…

Populations and Evolution · Quantitative Biology 2020-11-23 Krzysztof Bartoszek

Inference of species networks from genomic data under the Network Multispecies Coalescent Model is currently severely limited by heavy computational demands. It also remains unclear how complicated networks can be for consistent inference…

Populations and Evolution · Quantitative Biology 2022-05-10 Elizabeth S. Allman , Hector Baños , Jonathan D. Mitchell , John A. Rhodes

Phylogenetic inference, the task of reconstructing how related sequences evolved from common ancestors, is a central objective in evolutionary genomics. The current state-of-the-art methods exploit probabilistic models of sequence evolution…

Populations and Evolution · Quantitative Biology 2026-02-19 Luc Blassel , Noémie Sauvage , Pierre Barrat-Charlaix , Bastien Boussau , Nicolas Lartillot , Laurent Jacob

Correlations between two variables of a high-dimensional system can be indicative of an underlying interaction, but can also result from indirect effects. Inverse Ising inference is a method to distinguish one from the other. Essentially,…

Populations and Evolution · Quantitative Biology 2014-12-10 Benedikt Obermayer , Erel Levine

A method was developed for Bayesian inference of species phylogeny using the multi-species coalescent model. To improve the mixing properties of the Markov chain Monte Carlo (MCMC) algorithm that traverses the space of species trees, we…

Populations and Evolution · Quantitative Biology 2015-12-15 Bruce Rannala , Ziheng Yang

In this paper we investigate the geometry of a discrete Bayesian network whose graph is a tree all of whose variables are binary and the only observed variables are those labeling its leaves. We provide the full geometric description of…

Statistics Theory · Mathematics 2011-10-20 Piotr Zwiernik , Jim Q. Smith

In biology, a phylogenetic tree is a tool to represent the evolutionary relationship between species. Unfortunately, the classical Schr\"oder tree model is not adapted to take into account the chronology between the branching nodes. In…

Data Structures and Algorithms · Computer Science 2019-01-15 Olivier Bodini , Antoine Genitrini , Mehdi Naima

The problem of reconstructing evolutionary trees or phylogenies is of great interest in computational biology. A popular model for this problem assumes that we are given the set of leaves (current species) of an unknown binary tree and the…

Data Structures and Algorithms · Computer Science 2022-06-16 Eshwar Ram Arunachaleswaran , Anindya De , Sampath Kannan