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In the field of disparities research, there has been growing interest in developing a counterfactual-based decomposition analysis to identify underlying mediating mechanisms that help reduce disparities in populations. Despite rapid…

Methodology · Statistics 2022-05-27 Soojin Park , Chioun Lee , Xu Qin

Methods utilizing instrumental variables have been a fundamental statistical approach to estimation in the presence of unmeasured confounding, usually occurring in non-randomized observational data common to fields such as economics and…

Methodology · Statistics 2022-10-06 Charles Spanbauer , Wei Pan

The knowledge of transitions between regular, laminar or chaotic behavior is essential to understand the underlying mechanisms behind complex systems. While several linear approaches are often insufficient to describe such processes, there…

Medical Physics · Physics 2007-05-23 N. Marwan , N. Wessel , U. Meyerfeldt , A. Schirdewan , J. Kurths

Observational studies provide invaluable opportunities to draw causal inference, but they may suffer from biases due to pretreatment difference between treated and control units. Matching is a popular approach to reduce observed covariate…

Methodology · Statistics 2025-09-17 Xinran Li

Many standard structural quantities, such as order parameters and correlation functions, exist for common condensed matter systems, such as spherical and rod-like particles. However, these structural quantities are often insufficient for…

Soft Condensed Matter · Physics 2012-01-18 Aaron S. Keys , Christopher R. Iacovella , Sharon C. Glotzer

Morphological features of small vessels provide invaluable information regarding underlying tissue, especially in cancerous tumors. This paper introduces methods for obtaining quantitative morphological features from microvasculature images…

Medical Physics · Physics 2018-12-11 Siavash Ghavami , Mahdi Bayat , Mostafa Fatemi , Azra Alizad

We consider the problem of precision matrix estimation where, due to extraneous confounding of the underlying precision matrix, the data are independent but not identically distributed. While such confounding occurs in many scientific…

Machine Learning · Statistics 2019-07-01 Sinong Geng , Mladen Kolar , Oluwasanmi Koyejo

This article introduces a full mathematical and numerical framework for treating functional shapes (or fshapes) following the landmarks of shape spaces and shape analysis. Functional shapes can be described as signal functions supported on…

Computational Geometry · Computer Science 2014-04-25 Benjamin Charlier , Nicolas Charon , Alain Trouvé

Background. Emerging technologies now allow for mass spectrometry based profiling of up to thousands of small molecule metabolites (metabolomics) in an increasing number of biosamples. While offering great promise for revealing insight into…

Motivated by two case studies using primary care records from the Clinical Practice Research Datalink, we describe statistical methods that facilitate the analysis of tall data, with very large numbers of observations. Our focus is on…

Methodology · Statistics 2018-05-14 Kirsty Rhodes , Rebecca Turner , Rupert Payne , Ian White

A new technique is presented for producing images from interferometric data. The method, ``smear fitting'', makes the constraints necessary for interferometric imaging double as a model, with uncertainties, of the sky brightness…

Astrophysics · Physics 2009-11-11 Robert I. Reid

The study of pathological cardiac conditions such as arrhythmias, a major cause of mortality in heart failure, is becoming increasingly informed by computational simulation, numerically modelling the governing equations. This can provide…

Computational Engineering, Finance, and Science · Computer Science 2014-06-09 Nathan Kirk , Alan Benson , Christopher Goodyer , Matthew Hubbard

In the field of heart disease classification, two primary obstacles arise. Firstly, existing Electrocardiogram (ECG) datasets consistently demonstrate imbalances and biases across various modalities. Secondly, these time-series data consist…

Machine Learning · Computer Science 2024-07-31 Thao Hoang , Linh Nguyen , Khoi Do , Duong Nguyen , Viet Dung Nguyen

Purpose: This study proposes a novel anatomically-driven dynamic modeling framework for coronary arteries using skeletal skinning weights computation, aiming to achieve precise control over vessel deformation while maintaining real-time…

Graphics · Computer Science 2025-03-05 Shuo Wang , Tong Ren , Nan Cheng , Rong Wang , Li Zhang

The deconfounder was proposed as a method for estimating causal parameters in a context with multiple causes and unobserved confounding. It is based on recovery of a latent variable from the observed causes. We disentangle the causal…

Statistics Theory · Mathematics 2024-03-04 Jeffrey Adams , Niels Richard Hansen

The human heart is a sophisticated system composed of four cardiac chambers with distinct shapes, which function in a coordinated manner. Existing shape models of the heart mainly focus on the ventricular chambers and they are derived from…

Image and Video Processing · Electrical Eng. & Systems 2026-03-31 Qiang Ma , Qingjie Meng , Yicheng Wu , Shuo Wang , Mengyun Qiao , Steven Niederer , Declan P. O'Regan , Paul M. Matthews , Wenjia Bai

This paper provides theoretical and computational developments in statistical shape analysis of shape graphs, and demonstrates them using analysis of complex data from retinal blood-vessel (RBV) networks. The shape graphs are represented by…

Methodology · Statistics 2022-11-29 Aditi Basu Bal , Xiaoyang Guo , Tom Needham , Anuj Srivastava

In observational studies, potential unobserved confounding is a major barrier in isolating the average causal effect (ACE). In these scenarios, two main approaches are often used: confounder adjustment for causality (CAC) and instrumental…

Methodology · Statistics 2024-11-26 Roy S. Zawadzki , Daniel L. Gillen

Counterfactual data augmentation has recently emerged as a method to mitigate confounding biases in the training data. These biases, such as spurious correlations, arise due to various observed and unobserved confounding variables in the…

Machine Learning · Computer Science 2023-11-22 Abbavaram Gowtham Reddy , Saketh Bachu , Saloni Dash , Charchit Sharma , Amit Sharma , Vineeth N Balasubramanian

Heart failure (HF) affects at least 26 million people worldwide, so predicting adverse events in HF patients represents a major target of clinical data science. However, achieving large sample sizes sometimes represents a challenge due to…