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Echocardiography plays a fundamental role in the extraction of important clinical parameters (e.g. left ventricular volume and ejection fraction) required to determine the presence and severity of heart-related conditions. When deploying…

Computer Vision and Pattern Recognition · Computer Science 2025-02-19 Thierry Judge , Olivier Bernard , Woo-Jin Cho Kim , Alberto Gomez , Arian Beqiri , Agisilaos Chartsias , Pierre-Marc Jodoin

Clinical investigations of anatomy's structural changes over time could greatly benefit from population-level quantification of shape, or spatiotemporal statistic shape modeling (SSM). Such a tool enables characterizing patient organ cycles…

Machine Learning · Computer Science 2022-09-08 Jadie Adams , Nawazish Khan , Alan Morris , Shireen Elhabian

We present a robust method to find region-level correspondences between shapes, which are invariant to changes in geometry and applicable across multiple shape representations. We generate simplified shape graphs by jointly decomposing the…

Graphics · Computer Science 2018-03-06 Yanir Kleiman , Maks Ovsjanikov

Statistical shape modeling (SSM) directly from 3D medical images is an underutilized tool for detecting pathology, diagnosing disease, and conducting population-level morphology analysis. Deep learning frameworks have increased the…

Computer Vision and Pattern Recognition · Computer Science 2022-05-17 Jadie Adams , Shireen Elhabian

Much research has been devoted to the problem of estimating treatment effects from observational data; however, most methods assume that the observed variables only contain confounders, i.e., variables that affect both the treatment and the…

Machine Learning · Computer Science 2021-04-27 Weijia Zhang , Lin Liu , Jiuyong Li

This paper proposes a new approach to address the problem of unmeasured confounding in spatial designs. Spatial confounding occurs when some confounding variables are unobserved and not included in the model, leading to distorted…

Methodology · Statistics 2025-03-05 Carlo Zaccardi , Pasquale Valentini , Luigi Ippoliti , Alexandra M. Schmidt

Accurate estimation of shape thickness from medical images is crucial in clinical applications. For example, the thickness of myocardium is one of the key to cardiac disease diagnosis. While mathematical models are available to obtain…

Image and Video Processing · Electrical Eng. & Systems 2020-08-26 Qiaoying Huang , Eric Z. Chen , Hanchao Yu , Yimo Guo , Terrence Chen , Dimitris Metaxas , Shanhui Sun

Causal decomposition analysis provides a way to identify mediators that contribute to health disparities between marginalized and non-marginalized groups. In particular, the degree to which a disparity would be reduced or remain after…

Methodology · Statistics 2021-09-16 Soojin Park , Suyeon Kang , Chioun Lee

The classification of shapes is of great interest in diverse areas ranging from medical imaging to computer vision and beyond. While many statistical frameworks have been developed for the classification problem, most are strongly tied to…

Machine Learning · Statistics 2019-01-24 Min Ho Cho , Sebastian Kurtek , Steven N. MacEachern

Adjusting for an unmeasured confounder is generally an intractable problem, but in the spatial setting it may be possible under certain conditions. In this paper, we derive necessary conditions on the coherence between the treatment…

Methodology · Statistics 2020-12-23 Yawen Guan , Garritt L. Page , Brian J Reich , Massimo Ventrucci , Shu Yang

One obstacle to ``elevating" correlation to causation is the phenomenon of confounding, i.e., when a correlation between two variables exists because both variables are in fact caused by a third variable. The situation where the confounders…

Applications · Statistics 2025-06-24 Caren Marzban , Yikun Zhang , Nicholas Bond , Michael Richman

Statistical shape modeling is the computational process of discovering significant shape parameters from segmented anatomies captured by medical images (such as MRI and CT scans), which can fully describe subject-specific anatomy in the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Krithika Iyer , Shireen Elhabian

Valid estimation of treatment effects from observational data requires proper control of confounding. If the number of covariates is large relative to the number of observations, then controlling for all available covariates is infeasible.…

Methodology · Statistics 2018-01-11 Joseph Antonelli , Matthew Cefalu , Nathan Palmer , Denis Agniel

Unmeasured confounding is a major challenge for identifying causal relationships from non-experimental data. Here, we propose a method that can accommodate unmeasured discrete confounding. Extending recent identifiability results in deep…

Machine Learning · Computer Science 2024-08-13 Patrick Burauel , Frederick Eberhardt , Michel Besserve

With systems for acquiring 3D surface data being evermore commonplace, it has become important to reliably extract specific shapes from the acquired data. In the presence of noise and occlusions, this can be done through the use of…

Computer Vision and Pattern Recognition · Computer Science 2015-03-30 Alan Brunton , Augusto Salazar , Timo Bolkart , Stefanie Wuhrer

Large prospective epidemiological studies acquire cardiovascular magnetic resonance (CMR) images for pre-symptomatic populations and follow these over time. To support this approach, fully automatic large-scale 3D analysis is essential. In…

Image and Video Processing · Electrical Eng. & Systems 2019-07-04 Rahman Attar , Marco Pereanez , Christopher Bowles , Stefan K. Piechnik , Stefan Neubauer , Steffen E. Petersen , Alejandro F. Frangi

Respiratory motion and the associated deformations of abdominal organs and tumors are essential information in clinical applications. However, inter- and intra-patient multi-organ deformations are complex and have not been statistically…

Computer Vision and Pattern Recognition · Computer Science 2020-11-04 Megumi Nakao , Mitsuhiro Nakamura , Takashi Mizowaki , Tetsuya Matsuda

Measurement error is a pervasive issue which renders the results of an analysis unreliable. The measurement error literature contains numerous correction techniques, which can be broadly divided into those which aim to produce exactly…

Methodology · Statistics 2021-11-08 Dylan Spicker , Michael P Wallace , Grace Y Yi

In this paper, we propose a novel graph-based data augmentation method that can generally be applied to medical waveform data with graph structures. In the process of recording medical waveform data, such as electrocardiogram (ECG) or…

Machine Learning · Computer Science 2025-02-11 Kyung Geun Kim , Byeong Tak Lee

Atlas-based approaches allow high-quality, patient-specific shape reconstructions of cardiac anatomy from sparse and/or noisy data such as point clouds. However, these methods are mainly prior-driven, so the impact of uncertainty can be…

Image and Video Processing · Electrical Eng. & Systems 2026-05-11 Jan Verhülsdonk , Thomas Grandits , Francisco Sahli Costabal , Thomas Beiert , Simone Pezzuto , Alexander Effland