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Approximate Bayesian computation (ABC) using a sequential Monte Carlo method provides a comprehensive platform for parameter estimation, model selection and sensitivity analysis in differential equations. However, this method, like other…

Machine Learning · Statistics 2015-07-21 Sanmitra Ghosh , Srinandan Dasmahapatra , Koushik Maharatna

Accurate forecasts of COVID-19 is central to resource management and building strategies to deal with the epidemic. We propose a heterogeneous infection rate model with human mobility for epidemic modeling, a preliminary version of which we…

Populations and Evolution · Quantitative Biology 2020-05-06 Ajitesh Srivastava , Viktor K. Prasanna

We present a new method for analyzing stochastic epidemic models under minimal assumptions. The method, dubbed DSA, is based on a simple yet powerful observation, namely that population-level mean-field trajectories described by a system of…

Populations and Evolution · Quantitative Biology 2022-02-22 Francesco Di Lauro , Wasiur R. KhudaBukhsh , Istvan Z. Kiss , Eben Kenah , Max Jensen , Grzegorz A. Rempala

In this paper, we propose a deep learning model to forecast the range of increase in COVID-19 infected cases in future days and we present a novel method to compute equidimensional representations of multivariate time series and…

Computers and Society · Computer Science 2020-08-04 Ankit Ramchandani , Chao Fan , Ali Mostafavi

Determinants of COVID-19 clinical severity are commonly assessed by transverse or longitudinal studies of the fatality counts. However, the fatality counts depend both on disease clinical severity and transmissibility, as more infected also…

Populations and Evolution · Quantitative Biology 2021-09-02 Sofija Markovic , Andjela Rodic , Igor Salom , Ognjen Milicevic , Magdalena Djordjevic , Marko Djordjevic

Complex and nonlinear dynamical systems often involve parameters that change with time, accurate tracking of which is essential to tasks such as state estimation, prediction, and control. Existing machine-learning methods require full state…

Machine Learning · Computer Science 2023-11-16 Zheng-Meng Zhai , Mohammadamin Moradi , Bryan Glaz , Mulugeta Haile , Ying-Cheng Lai

Parameter estimation for dynamical systems remains challenging due to non-convexity and sensitivity to initial parameter guesses. Recent deep learning approaches enable accurate and fast parameter estimation but do not exploit transferable…

Systems and Control · Electrical Eng. & Systems 2026-04-08 Fabian Raisch , Timo Germann , J. Nathan Kutz , Christoph Goebel , Benjamin Tischler

Computer simulations have become an important tool across the biomedical sciences and beyond. For many important problems several different models or hypotheses exist and choosing which one best describes reality or observed data is not…

Quantitative Methods · Quantitative Biology 2010-01-20 Tina Toni , Michael P. H. Stumpf

The process of calibrating computer models of natural phenomena is essential for applications in the physical sciences, where plenty of domain knowledge can be embedded into simulations and then calibrated against real observations. Current…

Machine Learning · Computer Science 2025-01-20 Rafael Oliveira , Dino Sejdinovic , David Howard , Edwin V. Bonilla

This paper proposes a novel approach to predict epidemiological parameters by integrating new real-time signals from various sources of information, such as novel social media-based population density maps and Air Quality data. We implement…

Machine Learning · Computer Science 2023-07-04 Romain Molinas , César Quilodrán Casas , Rossella Arcucci , Ovidiu Şerban

The emergence of an epidemic evokes the need to monitor its spread and assess and validate any mitigation measures enacted by governments and administrative bodies in real time. We present here a method to observe and quantify this spread…

Populations and Evolution · Quantitative Biology 2024-11-06 Justin Trujillo , Valerica Raicu

The equations of complex dynamical systems may not be identified by expert knowledge, especially if the underlying mechanisms are unknown. Data-driven discovery methods address this challenge by inferring governing equations from…

Machine Learning · Computer Science 2026-02-05 Amit K. Chakraborty , Hao Wang , Pouria Ramazi

Widespread growth signatures in COVID-19 confirmed case counts are reported, with sharp transitions between three distinct dynamical regimes (exponential, superlinear and sublinear). Through analytical and numerical analysis, a novel…

Populations and Evolution · Quantitative Biology 2021-03-26 Magdalena Djordjevic , Marko Djordjevic , Bojana Ilic , Stefan Stojku , Igor Salom

Efficient skill acquisition, representation, and on-line adaptation to different scenarios has become of fundamental importance for assistive robotic applications. In the past decade, dynamical systems (DS) have arisen as a flexible and…

Robotics · Computer Science 2020-03-27 Matteo Saveriano , Dongheui Lee

The COVID-19 pandemic has created an urgent need for robust, scalable monitoring tools supporting stratification of high-risk patients. This research aims to develop and validate prediction models, using the UK Biobank, to estimate COVID-19…

For many tasks of data analysis, we may only have the information of the explanatory variable and the evaluation of the response values are quite expensive. While it is impractical or too costly to obtain the responses of all units, a…

Computation · Statistics 2023-04-07 Wei Zheng , Ting Tian , Xueqin Wang

Understanding protein conformational dynamics is essential for elucidating biological function but remains challenging due to the wide range of timescales and the complexity of collective motions. Enhanced sampling methods overcome…

Statistical Mechanics · Physics 2026-05-11 Souvik Mondal , Michael A. Sauer , Matthias Heyden

Macroscopic dynamical descriptions of complex physical systems are crucial for understanding and controlling material behavior. With the growing availability of data and compute, machine learning has become a promising alternative to…

Computational Physics · Physics 2026-03-24 Mengyi Chen , Pengru Huang , Kostya S. Novoselov , Qianxiao Li

Interest in the study of in-host microbial communities has increased in recent years due to our improved understanding of the communities' significant role in host health. As a result, the ability to model these communities using…

Quantitative Methods · Quantitative Biology 2015-09-24 Matthias Chung , Justin Krueger , Mihai Pop

We consider the problem of estimating the expected value of information (the knowledge gradient) for Bayesian learning problems where the belief model is nonlinear in the parameters. Our goal is to maximize some metric, while simultaneously…

Machine Learning · Statistics 2016-11-23 Xinyu He , Warren B. Powell
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