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Temporal Point Processes (TPP) are probabilistic generative frameworks. They model discrete event sequences localized in continuous time. Generally, real-life events reveal descriptive information, known as marks. Marked TPPs model time and…

Machine Learning · Computer Science 2024-11-26 Govind Waghmare , Ankur Debnath , Siddhartha Asthana , Aakarsh Malhotra

Electronic Medical Records (EHR) are extremely sparse. Only a small proportion of events (symptoms, diagnoses, and treatments) are observed in the lifetime of an individual. The high degree of missingness of EHR can be attributed to a large…

Artificial Intelligence · Computer Science 2021-11-18 Ramon Vinas , Xu Zheng , Jer Hayes

Although increasingly used as a data resource for assembling cohorts, electronic health records (EHRs) pose many analytic challenges. In particular, a patient's health status influences when and what data are recorded, generating sampling…

Methodology · Statistics 2020-04-28 Yifei Sun , Charles E. McCulloch , Kieren A. Marr , Chiung-Yu Huang

Modeling event sequences of multiple event types with marked temporal point processes (MTPPs) provides a principled way to uncover governing dynamical rules and predict future events. Current neural network approaches to MTPP inference rely…

Machine Learning · Computer Science 2026-03-02 David Berghaus , Patrick Seifner , Kostadin Cvejoski , César Ojeda , Ramsés J. Sánchez

EHR audit logs are a highly granular stream of events that capture clinician activities, and is a significant area of interest for research in characterizing clinician workflow on the electronic health record (EHR). Existing techniques to…

Computation and Language · Computer Science 2023-11-28 Benjamin C. Warner , Thomas Kannampallil , Seunghwan Kim

Electronic health records (EHR) consist of longitudinal clinical observations portrayed with sparsity, irregularity, and high-dimensionality, which become major obstacles in drawing reliable downstream clinical outcomes. Although there…

Machine Learning · Computer Science 2020-11-17 Ahmad Wisnu Mulyadi , Eunji Jun , Heung-Il Suk

Deep Learning based models are currently dominating most state-of-the-art solutions for disease prediction. Existing works employ RNNs along with multiple levels of attention mechanisms to provide interpretability. These deep learning…

Machine Learning · Statistics 2022-06-01 Subhadip Maji , Raghav Bali , Sree Harsha Ankem , Kishore V Ayyadevara

Background: Natural Language Processing (NLP) is widely used to extract clinical insights from Electronic Health Records (EHRs). However, the lack of annotated data, automated tools, and other challenges hinder the full utilisation of NLP…

Computation and Language · Computer Science 2023-06-23 Elias Hossain , Rajib Rana , Niall Higgins , Jeffrey Soar , Prabal Datta Barua , Anthony R. Pisani , Ph. D , Kathryn Turner}

Understanding deep learning model behavior is critical to accepting machine learning-based decision support systems in the medical community. Previous research has shown that jointly using clinical notes with electronic health record (EHR)…

Machine Learning · Computer Science 2022-12-07 Severin Husmann , Hugo Yèche , Gunnar Rätsch , Rita Kuznetsova

Foundational marked temporal point process (MTPP) models, such as the Hawkes process, often use inexpressive model families in order to offer interpretable parameterizations of event data. On the other hand, neural MTPPs models forego this…

Machine Learning · Statistics 2025-11-04 Alex Boyd , Andrew Warrington , Taha Kass-Hout , Parminder Bhatia , Danica Xiao

The surging availability of electronic medical records (EHR) leads to increased research interests in medical predictive modeling. Recently many deep learning based predicted models are also developed for EHR data and demonstrated…

Machine Learning · Computer Science 2018-02-15 Mengying Sun , Fengyi Tang , Jinfeng Yi , Fei Wang , Jiayu Zhou

Sepsis remains one of the most complex and heterogeneous syndromes in intensive care, characterized by diverse physiological trajectories and variable responses to treatment. While deep learning models perform well in the early prediction…

Machine Learning · Computer Science 2026-04-01 Vincent Lemaire , Nédra Meloulli , Pierre Jaquet

Temporal point processes are powerful generative models for event sequences that capture complex dependencies in time-series data. They are commonly specified using autoregressive models that learn the distribution of the next event from…

Machine Learning · Computer Science 2025-10-24 Marin Biloš , Anderson Schneider , Yuriy Nevmyvaka

Electronic phenotyping is the task of ascertaining whether an individual has a medical condition of interest by analyzing their medical record and is foundational in clinical informatics. Increasingly, electronic phenotyping is performed…

Machine Learning · Statistics 2019-01-08 Daisy Yi Ding , Chloé Simpson , Stephen Pfohl , Dave C. Kale , Kenneth Jung , Nigam H. Shah

Predicting (1) when the next hospital admission occurs and (2) what will happen in the next admission about a patient by mining electronic health record (EHR) data can provide granular readmission predictions to assist clinical decision…

Machine Learning · Computer Science 2021-02-05 Bhagya Hettige , Weiqing Wang , Yuan-Fang Li , Suong Le , Wray Buntine

In recent years, we have witnessed an increased interest in temporal modeling of patient records from large scale Electronic Health Records (EHR). While simpler RNN models have been used for such problems, memory networks, which in other…

Machine Learning · Computer Science 2020-07-15 Prithwish Chakraborty , Fei Wang , Jianying Hu , Daby Sow

The introduction of electronic personal health records (EHR) enables nationwide information exchange and curation among different health care systems. However, the current EHR systems do not provide transparent means for diagnosis support,…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-10-04 Dragi Kimovski , Sasko Ristov , Radu Prodan

The classical temporal point process (TPP) constructs an intensity function by taking the occurrence times into account. Nevertheless, occurrence time may not be the only relevant factor, other contextual data, termed covariates, may also…

Machine Learning · Computer Science 2024-07-24 Zizhuo Meng , Boyu Li , Xuhui Fan , Zhidong Li , Yang Wang , Fang Chen , Feng Zhou

Due to potential applications in chronic disease management and personalized healthcare, the EHRs data analysis has attracted much attention of both researchers and practitioners. There are three main challenges in modeling longitudinal and…

Machine Learning · Computer Science 2019-12-03 Yi Huang , Xiaoshan Yang , Changsheng Xu

Electronic health records (EHRs) are increasingly recognized as a cost-effective resource for patient recruitment in clinical research. However, how to optimally select a cohort from millions of individuals to answer a scientific question…

Methodology · Statistics 2023-12-14 Guanghao Zhang , Lauren J. Beesley , Bhramar Mukherjee , Xu Shi