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This study proposes a risk prediction method based on a Multi-Scale Temporal Alignment Network (MSTAN) to address the challenges of temporal irregularity, sampling interval differences, and multi-scale dynamic dependencies in Electronic…

Machine Learning · Computer Science 2025-11-27 Wei-Chen Chang , Lu Dai , Ting Xu

Predictive modeling with electronic health record (EHR) data is anticipated to drive personalized medicine and improve healthcare quality. Constructing predictive statistical models typically requires extraction of curated predictor…

Evaluating the clinical similarities between pairwise patients is a fundamental problem in healthcare informatics. A proper patient similarity measure enables various downstream applications, such as cohort study and treatment comparative…

Machine Learning · Statistics 2019-02-12 Zihao Zhu , Changchang Yin , Buyue Qian , Yu Cheng , Jishang Wei , Fei Wang

Electronic health records (EHR) contain valuable longitudinal patient-level information, yet most statistical methods reduce the irregular timing of EHR codes into simple counts, thereby discarding rich temporal structure. Existing temporal…

Methodology · Statistics 2025-08-29 Parker Knight , Doudou Zhou , Zongqi Xia , Tianxi Cai , Junwei Lu

Event prediction in the continuous-time domain is a crucial but rather difficult task. Temporal point process (TPP) learning models have shown great advantages in this area. Existing models mainly focus on encoding global contexts of events…

Machine Learning · Computer Science 2023-06-27 Wang-Tao Zhou , Zhao Kang , Ling Tian , Yi Su

Deep learning-based modeling of multimodal Electronic Health Records (EHRs) has become an important approach for clinical diagnosis and risk prediction. However, due to diverse clinical workflows and privacy constraints, raw EHRs are…

Machine Learning · Computer Science 2026-04-09 Bohao Li , Tao Zou , Junchen Ye , Yan Gong , Bowen Du

While the volume of electronic health records (EHR) data continues to grow, it remains rare for hospital systems to capture dense physiological data streams, even in the data-rich intensive care unit setting. Instead, typical EHR records…

Machine Learning · Computer Science 2018-12-04 Satya Narayan Shukla , Benjamin M. Marlin

The shift to electronic medical records (EMRs) has engendered research into machine learning and natural language technologies to analyze patient records, and to predict from these clinical outcomes of interest. Two observations motivate…

Computation and Language · Computer Science 2019-04-09 Sarthak Jain , Ramin Mohammadi , Byron C. Wallace

Temporal Point Processes (TPPs) have been widely used for modeling event sequences on the Web, such as user reviews, social media posts, and online transactions. However, traditional TPP models often struggle to effectively incorporate the…

Computation and Language · Computer Science 2026-03-19 Quyu Kong , Yixuan Zhang , Yang Liu , Panrong Tong , Enqi Liu , Feng Zhou

In this work, we identify open research opportunities in applying Neural Temporal Point Process (NTPP) models to industry scale customer behavior data by carefully reproducing NTPP models published up to date on known literature benchmarks…

Machine Learning · Computer Science 2022-08-19 Dominykas Šeputis , Jevgenij Gamper , Remigijus Paulavičius

We develop an unsupervised probabilistic model for heterogeneous Electronic Health Record (EHR) data. Utilizing a mixture model formulation, our approach directly models sequences of arbitrary length, such as medications and laboratory…

Machine Learning · Computer Science 2022-09-02 Alan D. Kaplan , John D. Greene , Vincent X. Liu , Priyadip Ray

Temporal point process (TPP) is commonly used to model the asynchronous event sequence featuring occurrence timestamps and revealed by probabilistic models conditioned on historical impacts. While lots of previous works have focused on…

Machine Learning · Computer Science 2022-08-05 Haitao Lin , Lirong Wu , Guojiang Zhao , Pai Liu , Stan Z. Li

A temporal point process is a stochastic process that predicts which type of events is likely to happen and when the event will occur given a history of a sequence of events. There are various examples of occurrence dynamics in the daily…

Machine Learning · Computer Science 2022-02-23 Deokjun Eom , Sehyun Lee , Jaesik Choi

Temporal point processes (TPPs) are widely used to model the timing and occurrence of events in domains such as social networks, transportation systems, and e-commerce. In this paper, we introduce TPP-LLM, a novel framework that integrates…

Machine Learning · Computer Science 2025-06-11 Zefang Liu , Yinzhu Quan

Temporal Point Processes (TPPs) are often used to represent the sequence of events ordered as per the time of occurrence. Owing to their flexible nature, TPPs have been used to model different scenarios and have shown applicability in…

Machine Learning · Computer Science 2021-07-19 Shivshankar Reddy , Anand Vir Singh Chauhan , Maneet Singh , Karamjit Singh

Temporal point process (TPP) models combined with recurrent neural networks provide a powerful framework for modeling continuous-time event data. While such models are flexible, they are inherently sequential and therefore cannot benefit…

Machine Learning · Computer Science 2020-11-11 Oleksandr Shchur , Nicholas Gao , Marin Biloš , Stephan Günnemann

The large volumes of data generated by human activities such as online purchases, health records, spatial mobility etc. are stored as a sequence of events over a continuous time. Learning deep learning methods over such sequences is a…

Machine Learning · Computer Science 2021-11-16 Vinayak Gupta

Databases of electronic health records (EHRs) are increasingly used to inform clinical decisions. Machine learning methods can find patterns in EHRs that are predictive of future adverse outcomes. However, statistical models may be built…

Machine Learning · Statistics 2018-12-04 Andrew C. Miller , Ziad Obermeyer , Sendhil Mullainathan

The widespread application of Electronic Health Records (EHR) data in the medical field has led to early successes in disease risk prediction using deep learning methods. These methods typically require extensive data for training due to…

Machine Learning · Computer Science 2024-11-28 Shibo Li , Hengliang Cheng , Weihua Li

Marked Temporal Point Processes (MTPPs) arise naturally in medical, social, commercial, and financial domains. However, existing Transformer-based methods mostly inject temporal information only via positional encodings, relying on shared…

Machine Learning · Computer Science 2026-03-25 Xinzi Tan , Kejian Zhang , Junhan Yu , Doudou Zhou