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Drug-drug interaction (DDI) prediction is central to drug discovery and clinical development, particularly in the context of increasingly prevalent polypharmacy. Although existing computational methods achieve strong performance on standard…

Machine Learning · Computer Science 2026-01-23 Dong Xu , Jiantao Wu , Qihua Pan , Sisi Yuan , Zexuan Zhu , Junkai Ji

In order to enable high-quality decision making and motion planning of intelligent systems such as robotics and autonomous vehicles, accurate probabilistic predictions for surrounding interactive objects is a crucial prerequisite. Although…

Robotics · Computer Science 2019-04-05 Jiachen Li , Hengbo Ma , Masayoshi Tomizuka

Active inference helps us simulate adaptive behavior and decision-making in biological and artificial agents. Building on our previous work exploring the relationship between active inference, well-being, resilience, and sustainability, we…

Artificial Intelligence · Computer Science 2024-06-13 Mahault Albarracin , Ines Hipolito , Maria Raffa , Paul Kinghorn

Deep reinforcement learning (DRL) provides a promising way for intelligent agents (e.g., autonomous vehicles) to learn to navigate complex scenarios. However, DRL with neural networks as function approximators is typically considered a…

Robotics · Computer Science 2023-11-28 Jiachen Li , David Isele , Kanghoon Lee , Jinkyoo Park , Kikuo Fujimura , Mykel J. Kochenderfer

Active inference is a mathematical framework for understanding how agents (biological or artificial) interact with their environments, enabling continual adaptation and decision-making. It combines Bayesian inference and free energy…

Artificial Intelligence · Computer Science 2024-10-02 Rithvik Prakki

Active Inference is an emerging framework providing a quantitative account of behavioral processes in neuroscience and a principled approach to decision-making under uncertainty. Its application to agency problems is natural, offering an…

Computational Engineering, Finance, and Science · Computer Science 2026-04-15 Francesco Maria Mancinelli , Matteo Torzoni , Domenico Maisto , Francesco Donnarumma , Alberto Corigliano , Giovanni Pezzulo , Andrea Manzoni

From pedestrians to Kuramoto oscillators, interactions between agents govern how dynamical systems evolve in space and time. Discovering how these agents relate to each other has the potential to improve our understanding of the often…

Machine Learning · Computer Science 2025-03-12 Yulong Yang , Bowen Feng , Keqin Wang , Naomi Ehrich Leonard , Adji Bousso Dieng , Christine Allen-Blanchette

Multi-Agent Deep Reinforcement Learning (MADRL) was proven efficient in solving complex problems in robotics or games, yet most of the trained models are hard to interpret. While learning intrinsically interpretable models remains a…

Artificial Intelligence · Computer Science 2025-02-04 Yoann Poupart , Aurélie Beynier , Nicolas Maudet

Trajectory prediction for scenes with multiple agents and entities is a challenging problem in numerous domains such as traffic prediction, pedestrian tracking and path planning. We present a general architecture to address this challenge…

Machine Learning · Computer Science 2020-11-02 Nitin Kamra , Hao Zhu , Dweep Trivedi , Ming Zhang , Yan Liu

Multiagent reinforcement learning, as a prominent intelligent paradigm, enables collaborative decision-making within complex systems. However, existing approaches often rely on explicit action exchange between agents to evaluate action…

Robotics · Computer Science 2026-01-09 Zhenglong Luo , Zhiyong Chen , Aoxiang Liu

Many potential applications of reinforcement learning in the real world involve interacting with other agents whose numbers vary over time. We propose new neural policy architectures for these multi-agent problems. In contrast to other…

Machine Learning · Computer Science 2019-06-03 Matthew A. Wright , Roberto Horowitz

The behavioral dynamics of multi-agent systems have a rich and orderly structure, which can be leveraged to understand these systems, and to improve how artificial agents learn to operate in them. Here we introduce Relational Forward Models…

We apply recent advances in deep generative modeling to the task of imitation learning from biological agents. Specifically, we apply variations of the variational recurrent neural network model to a multi-agent setting where we learn…

Machine Learning · Computer Science 2020-07-02 Michael Teng , Tuan Anh Le , Adam Scibior , Frank Wood

Effective modeling of group interactions and dynamic semantic intentions is crucial for forecasting behaviors like trajectories or movements. In complex scenarios like sports, agents' trajectories are influenced by group interactions and…

Computer Vision and Pattern Recognition · Computer Science 2024-12-23 Mengshi Qi , Yuxin Yang , Huadong Ma

The ability to predict the future trajectories of traffic participants is crucial for the safe and efficient operation of autonomous vehicles. In this paper, a diffusion-based generative model for multi-agent trajectory prediction is…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Theodor Westny , Björn Olofsson , Erik Frisk

To accurately predict trajectories in multi-agent settings, e.g. team games, it is important to effectively model the interactions among agents. Whereas a number of methods have been developed for this purpose, existing methods implicitly…

Computer Vision and Pattern Recognition · Computer Science 2022-10-25 Zikai Wei , Xinge Zhu , Bo Dai , Dahua Lin

Inferring the laws of interaction between particles and agents in complex dynamical systems from observational data is a fundamental challenge in a wide variety of disciplines. We propose a non-parametric statistical learning approach to…

Machine Learning · Computer Science 2022-06-08 Fei Lu , Mauro Maggioni , Sui Tang , Ming Zhong

We study the problem of training sequential generative models for capturing coordinated multi-agent trajectory behavior, such as offensive basketball gameplay. When modeling such settings, it is often beneficial to design hierarchical…

Machine Learning · Computer Science 2019-02-25 Eric Zhan , Stephan Zheng , Yisong Yue , Long Sha , Patrick Lucey

Artificial intelligence systems increasingly involve continual learning to enable flexibility in general situations that are not encountered during system training. Human interaction with autonomous systems is broadly studied, but research…

Effective coordination and cooperation among agents are crucial for accomplishing individual or shared objectives in multi-agent systems. In many real-world multi-agent systems, agents possess varying abilities and constraints, making it…

Multiagent Systems · Computer Science 2023-10-20 Yasin Findik , Paul Robinette , Kshitij Jerath , S. Reza Ahmadzadeh