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Related papers: Energy-based View of Retrosynthesis

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Leveraging artificial intelligence for automatic retrosynthesis speeds up organic pathway planning in digital laboratories. However, existing deep learning approaches are unexplainable, like "black box" with few insights, notably limiting…

Machine Learning · Computer Science 2023-10-13 Yu Wang , Chao Pang , Yuzhe Wang , Yi Jiang , Junru Jin , Sirui Liang , Quan Zou , Leyi Wei

Fine-grained open-set recognition (FineOSR) aims to recognize images belonging to classes with subtle appearance differences while rejecting images of unknown classes. A recent trend in OSR shows the benefit of generative models to…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Wentao Bao , Qi Yu , Yu Kong

We note that most existing approaches for molecular graph generation fail to guarantee the intrinsic property of permutation invariance, resulting in unexpected bias in generative models. In this work, we propose GraphEBM to generate…

Machine Learning · Computer Science 2021-04-13 Meng Liu , Keqiang Yan , Bora Oztekin , Shuiwang Ji

Energy-Based Models (EBMs), also known as non-normalized probabilistic models, specify probability density or mass functions up to an unknown normalizing constant. Unlike most other probabilistic models, EBMs do not place a restriction on…

Machine Learning · Computer Science 2021-02-19 Yang Song , Diederik P. Kingma

In domains with interdependent data, such as graphs, quantifying the epistemic uncertainty of a Graph Neural Network (GNN) is challenging as uncertainty can arise at different structural scales. Existing techniques neglect this issue or…

Machine Learning · Computer Science 2025-02-28 Dominik Fuchsgruber , Tom Wollschläger , Stephan Günnemann

We present E NERGY N ET , a new framework for analyzing and building artificial neural network architectures. Our approach adaptively learns the structure of the networks in an unsupervised manner. The methodology is based upon the…

Machine Learning · Computer Science 2017-11-10 Gus Kristiansen , Xavi Gonzalvo

Consider learning a policy purely on the basis of demonstrated behavior -- that is, with no access to reinforcement signals, no knowledge of transition dynamics, and no further interaction with the environment. This *strictly batch…

Machine Learning · Statistics 2021-01-15 Daniel Jarrett , Ioana Bica , Mihaela van der Schaar

We introduce a mathematical framework for retrosynthetic analysis, an important research method in synthetic chemistry. Our approach represents molecules and their interaction using string diagrams in layered props - a recently introduced…

Logic in Computer Science · Computer Science 2023-11-08 Ella Gale , Leo Lobski , Fabio Zanasi

We cast retrosynthesis as a machine translation problem by introducing a special Tensor2Tensor, an entire attention-based and fully data-driven model. Given a data set comprising about 50,000 diverse reactions extracted from USPTO patents,…

Chemical Physics · Physics 2019-08-05 Hongliang Duan , Ling Wang , Chengyun Zhang , Jianjun Li

Machine learning-based compact models provide a rapid and efficient approach for estimating device behavior across multiple input parameter variations. In this study, we introduce two reverse-design algorithms that utilize these compact…

Emerging Technologies · Computer Science 2025-08-29 Diego Ferrer , Jack Hutchins , Revanth Koduru , Sumeet Kumar Gupta , Admedullah Aziz

Automated Synthesis Planning has recently re-emerged as a research area at the intersection of chemistry and machine learning. Despite the appearance of steady progress, we argue that imperfect benchmarks and inconsistent comparisons mask…

Machine Learning · Computer Science 2024-09-09 Krzysztof Maziarz , Austin Tripp , Guoqing Liu , Megan Stanley , Shufang Xie , Piotr Gaiński , Philipp Seidl , Marwin Segler

The pre-trained foundation models (PFMs) have become essential for facilitating large-scale multimodal learning. Researchers have effectively employed the ``pre-train, prompt, and predict'' paradigm through prompt learning to induce…

Computation and Language · Computer Science 2025-12-24 Xiang Chen , Yixin Ou , Quan Feng , Lei Li , Piji Li , Haibo Ye , Sheng-Jun Huang , Shuofei Qiao , Shumin Deng , Huajun Chen , Ningyu Zhang

Despite the progresses on pre-trained language models, there is a lack of unified frameworks for pre-trained sentence representation. As such, it calls for different pre-training methods for specific scenarios, and the pre-trained models…

Computation and Language · Computer Science 2022-08-02 Alexander Liu , Samuel Yang

We offer a study that connects robust discriminative classifiers trained with adversarial training (AT) with generative modeling in the form of Energy-based Models (EBM). We do so by decomposing the loss of a discriminative classifier and…

Machine Learning · Computer Science 2023-06-06 Senad Beadini , Iacopo Masi

Machine Learning has been applied in a wide range of tasks throughout the last years, ranging from image classification to autonomous driving and natural language processing. Restricted Boltzmann Machine (RBM) has received recent attention…

Machine Learning · Computer Science 2021-01-05 Gustavo H. de Rosa , Mateus Roder , João P. Papa

This work has been submitted to the IEEE for possible publication. Copyright may be transferred without notice, after which this version may no longer be accessible. In many applications, the spatial distribution of a field needs to be…

Machine Learning · Computer Science 2021-09-01 Roberto Ponciroli , Andrea Rovinelli , Lander Ibarra

Controllable generation is one of the key requirements for successful adoption of deep generative models in real-world applications, but it still remains as a great challenge. In particular, the compositional ability to generate novel…

Computer Vision and Pattern Recognition · Computer Science 2021-12-07 Weili Nie , Arash Vahdat , Anima Anandkumar

Recent advances in unimanual manipulation policies have achieved remarkable success across diverse robotic tasks through abundant training data and well-established model architectures. However, extending these capabilities to bimanual…

Robotics · Computer Science 2026-03-24 Mingchen Song , Xiang Deng , Jie Wei , Dongmei Jiang , Liqiang Nie , Weili Guan

Adversarial Training (AT) is known as an effective approach to enhance the robustness of deep neural networks. Recently researchers notice that robust models with AT have good generative ability and can synthesize realistic images, while…

Machine Learning · Computer Science 2022-03-28 Yifei Wang , Yisen Wang , Jiansheng Yang , Zhouchen Lin

While deep learning-based classification is generally tackled using standardized approaches, a wide variety of techniques are employed for regression. In computer vision, one particularly popular such technique is that of confidence-based…

Machine Learning · Computer Science 2020-07-21 Fredrik K. Gustafsson , Martin Danelljan , Goutam Bhat , Thomas B. Schön