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Light scattering and aberrations limit optical microscopy in biological tissue, which motivates the development of adaptive optics techniques. Here, we develop a method for adaptive optics with reflected light and deep neural networks…

Optics · Physics 2020-07-28 Ivan Vishniakou , Johannes D. Seelig

Aberrations limit scanning fluorescence microscopy when imaging in scattering materials such as biological tissue. Model-based approaches for adaptive optics take advantage of a computational model of the optical setup. Such models can be…

Optics · Physics 2021-07-07 Ivan Vishniakou , Johannes D. Seelig

Adaptive optics can focus light through opaque media by compensating the random phase delay acquired while crossing a scattering curtain. The technique is commonly exploited in many fields, including astrophysics, microscopy, biomedicine…

Optics · Physics 2015-06-24 Diego Di Battista , Giannis Zacharakis , Marco Leonetti

In optical imaging, light propagation is affected by the inhomogeneities of the medium. Sample-induced aberrations and multiple scattering can strongly degrade the image resolution and contrast. Based on a dynamic correction of the incident…

Scattering often limits the controlled delivery of light in applications such as biomedical imaging, optogenetics, optical trapping, and fiber-optic communication or imaging. Such scattering can be controlled by appropriately shaping the…

Optics · Physics 2019-02-19 Alex Turpin , Ivan Vishniakou , Johannes D. Seelig

Optical aberrations of optical systems cause significant degradation of imaging quality. Aberration correction by sophisticated lens designs and special glass materials generally incurs high cost of manufacturing and the increase in the…

Computer Vision and Pattern Recognition · Computer Science 2023-04-13 Shuang Cui , Bingnan Wang , Quan Zheng

Microscope objectives achieve near diffraction-limited performance only when used under the conditions they are designed for. In non-standard geometries, such as thick cover slips or curved surfaces, severe aberrations arise, inevitably…

Optics · Physics 2025-03-24 D. W. S. Cox , T. Knop , I. M. Vellekoop

Optical aberrations prevent telescopes from reaching their theoretical diffraction limit. Once estimated, these aberrations can be compensated for using deformable mirrors in a closed loop. Focal plane wavefront sensing enables the…

Microscopy and optical imaging are drastically limited by the inhomogeneities encountered by the light while propagating from the object of interest to the detection system. In this context, adaptive optics and wavefront manipulation are…

Optics · Physics 2017-01-23 Diego Di Battista

Inhomogeneities in the refractive index of a biological sample can introduce phase aberrationsin microscopy systems, severely impairing the quality of images. Adaptive optics can be employed to correct for phase aberrations and improve…

Diffraction-limited focusing deep into biological tissue is challenging due to spherical aberrations that lead to a broadening of the focal spot particularly in axial direction. While the diffraction-limit can be restored employing…

We present a learning-based approach for removing unwanted obstructions, such as window reflections, fence occlusions or raindrops, from a short sequence of images captured by a moving camera. Our method leverages the motion differences…

Computer Vision and Pattern Recognition · Computer Science 2020-04-03 Yu-Lun Liu , Wei-Sheng Lai , Ming-Hsuan Yang , Yung-Yu Chuang , Jia-Bin Huang

The capability of the adaptive optics to correct for the segmentation error is analyzed in terms of the residual wavefront RMS and the power spectral density of the phase. The analytical model and the end-to-end simulation give…

Astrophysics · Physics 2009-11-11 Natalia Yaitskova , Christophe Verinaud

Many adaptive optics systems operate by measuring the distortion of the wavefront in one wavelength range and performing the scientific observations in a second, different wavelength range. One common technique is to measure wavefront…

Astrophysics · Physics 2009-11-07 Henry G. Roe

Adaptive optics is a strategy to compensate for sample-induced aberrations in microscopy applications. Generally, it requires the presence of "guide stars" in the sample to serve as localized reference targets. We describe an implementation…

Machine learning methods for computational imaging require uncertainty estimation to be reliable in real settings. While Bayesian models offer a computationally tractable way of recovering uncertainty, they need large data volumes to be…

Machine Learning · Computer Science 2020-08-24 Francesco Tonolini , Jack Radford , Alex Turpin , Daniele Faccio , Roderick Murray-Smith

Diffuse Reflectance Spectroscopy has demonstrated a strong aptitude for identifying and differentiating biological tissues. However, the broadband and smooth nature of these signals require algorithmic processing, as they are often…

Image and Video Processing · Electrical Eng. & Systems 2025-03-06 Nicola Rossberg , Celina L. Li , Simone Innocente , Stefan Andersson-Engels , Katarzyna Komolibus , Barry O'Sullivan , Andrea Visentin

Deep neural networks have been applied successfully to a wide variety of inverse problems arising in computational imaging. These networks are typically trained using a forward model that describes the measurement process to be inverted,…

Image and Video Processing · Electrical Eng. & Systems 2021-04-14 Davis Gilton , Gregory Ongie , Rebecca Willett

In planar metamaterial lenses, the focal point moves with the frequency. Here it is shown numerically that this movement can be controlled by properly engineering the dimensions of the metamaterial-based phase shifters that constitute the…

Optics · Physics 2013-03-01 W. J. Capecchi , N. Behdad , F. A. Volpe

Object detection for robot guidance is a crucial mission for autonomous robots, which has provoked extensive attention for researchers. However, the changing view of robot movement and limited available data hinder the research in this…

Computer Vision and Pattern Recognition · Computer Science 2019-11-21 Jingwen Fu , Licheng Zong , Yinbing Li , Ke Li , Bingqian Yang , Xibei Liu
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