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This article reviews recent advances in applying natural language processing (NLP) to Electronic Health Records (EHRs) for computational phenotyping. NLP-based computational phenotyping has numerous applications including diagnosis…

Computation and Language · Computer Science 2018-06-18 Zexian Zeng , Yu Deng , Xiaoyu Li , Tristan Naumann , Yuan Luo

Most recent work on interpretability of complex machine learning models has focused on estimating $\textit{a posteriori}$ explanations for previously trained models around specific predictions. $\textit{Self-explaining}$ models where…

Machine Learning · Computer Science 2018-12-05 David Alvarez-Melis , Tommi S. Jaakkola

Deep neural networks have been proven powerful at processing perceptual data, such as images and audio. However for tabular data, tree-based models are more popular. A nice property of tree-based models is their natural interpretability. In…

Machine Learning · Computer Science 2018-06-20 Yongxin Yang , Irene Garcia Morillo , Timothy M. Hospedales

In spite of several claims stating that some models are more interpretable than others -- e.g., "linear models are more interpretable than deep neural networks" -- we still lack a principled notion of interpretability to formally compare…

Artificial Intelligence · Computer Science 2020-11-16 Pablo Barceló , Mikaël Monet , Jorge Pérez , Bernardo Subercaseaux

Due to the powerful learning ability on high-rank and non-linear features, deep neural networks (DNNs) are being applied to data mining and machine learning in various fields, and exhibit higher discrimination performance than conventional…

Machine Learning · Computer Science 2023-02-21 Weiyu Guo , Zhijiang Yang , Shu Wu , Fu Chen

Nowadays, neural network (NN) and deep learning (DL) techniques are widely adopted in many applications, including recommender systems. Given the sparse and stochastic nature of collaborative filtering (CF) data, recent works have…

Information Retrieval · Computer Science 2024-07-03 Giuseppe Serra , Peter Tino , Zhao Xu , Xin Yao

The utilization of Electronic Health Records (EHRs) for clinical risk prediction is on the rise. However, strict privacy regulations limit access to comprehensive health records, making it challenging to apply standard machine learning…

Computation and Language · Computer Science 2023-12-08 Angeela Acharya , Sulabh Shrestha , Anyi Chen , Joseph Conte , Sanja Avramovic , Siddhartha Sikdar , Antonios Anastasopoulos , Sanmay Das

Modern electronic health records (EHRs) provide data to answer clinically meaningful questions. The growing data in EHRs makes healthcare ripe for the use of machine learning. However, learning in a clinical setting presents unique…

Machine Learning · Computer Science 2019-12-09 Marzyeh Ghassemi , Tristan Naumann , Peter Schulam , Andrew L. Beam , Irene Y. Chen , Rajesh Ranganath

This paper introduces the Actuarial Neural Additive Model, an inherently interpretable deep learning model for general insurance pricing that offers fully transparent and interpretable results while retaining the strong predictive power of…

Machine Learning · Computer Science 2025-09-11 Patrick J. Laub , Tu Pho , Bernard Wong

Artificial intelligence (AI) has demonstrated significant potential in transforming healthcare through the analysis and modeling of electronic health records (EHRs). However, the inherent heterogeneity, temporal irregularity, and…

Machine Learning · Computer Science 2025-07-18 Weijieying Ren , Jingxi Zhu , Zehao Liu , Tianxiang Zhao , Vasant Honavar

Advancements in sensing and computing technologies, the development of human and computer interaction frameworks, big data storage capabilities, and the emergence of cloud storage and could computing have resulted in an abundance of data in…

Machine Learning · Computer Science 2020-07-07 Ramin Moradi , Katrina M. Groth

Deep learning models have achieved state-of-the-art performance in many classification tasks. However, most of them cannot provide an interpretation for their classification results. Machine learning models that are interpretable are…

Machine Learning · Computer Science 2021-11-04 Miles Q. Li , Benjamin C. M. Fung , Adel Abusitta

Healthcare sector is totally different from other industry. It is on high priority sector and people expect highest level of care and services regardless of cost. It did not achieve social expectation even though it consume huge percentage…

Computer Vision and Pattern Recognition · Computer Science 2017-04-25 Muhammad Imran Razzak , Saeeda Naz , Ahmad Zaib

Although deep learning has achieved remarkable success in various scientific machine learning applications, its opaque nature poses concerns regarding interpretability and generalization capabilities beyond the training data.…

Machine Learning · Computer Science 2024-04-18 Amirhossein Arzani , Lingxiao Yuan , Pania Newell , Bei Wang

Learning an explainable classifier often results in low accuracy model or ends up with a huge rule set, while learning a deep model is usually more capable of handling noisy data at scale, but with the cost of hard to explain the result and…

Artificial Intelligence · Computer Science 2022-11-11 Yuanlong Li , Gaopan Huang , Min Zhou , Chuan Fu , Honglin Qiao , Yan He

Translating machine learning (ML) models effectively to clinical practice requires establishing clinicians' trust. Explainability, or the ability of an ML model to justify its outcomes and assist clinicians in rationalizing the model…

Machine Learning · Computer Science 2019-08-08 Sana Tonekaboni , Shalmali Joshi , Melissa D McCradden , Anna Goldenberg

The widespread availability of electronic health records (EHRs) promises to usher in the era of personalized medicine. However, the problem of extracting useful clinical representations from longitudinal EHR data remains challenging. In…

Machine Learning · Computer Science 2017-01-27 Zhengping Che , Yu Cheng , Zhaonan Sun , Yan Liu

Interpretability of machine learning models is critical for data-driven precision medicine efforts. However, highly predictive models are generally complex and are difficult to interpret. Here using Model-Agnostic Explanations algorithm, we…

Quantitative Methods · Quantitative Biology 2016-10-31 Gajendra Jung Katuwal , Robert Chen

Recent efforts to learn reward functions from human feedback have tended to use deep neural networks, whose lack of transparency hampers our ability to explain agent behaviour or verify alignment. We explore the merits of learning…

Machine Learning · Computer Science 2022-10-04 Tom Bewley , Jonathan Lawry , Arthur Richards , Rachel Craddock , Ian Henderson

Although deep models achieve high predictive performance, it is difficult for humans to understand the predictions they made. Explainability is important for real-world applications to justify their reliability. Many example-based…

Machine Learning · Statistics 2021-12-08 Tomoharu Iwata , Yuya Yoshikawa