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Robust and generalizable segmentation of brain tumors on multi-parametric magnetic resonance imaging (MRI) remains difficult because tumor types differ widely. The BraTS 2025 Lighthouse Challenge benchmarks segmentation methods on diverse…

This paper presents a novel method for unsupervised segmentation of pathology images. Staging of lung cancer is a major factor of prognosis. Measuring the maximum dimensions of the invasive component in a pathology images is an essential…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Takayasu Moriya , Holger R. Roth , Shota Nakamura , Hirohisa Oda , Kai Nagara , Masahiro Oda , Kensaku Mori

In medical applications, weakly supervised anomaly detection methods are of great interest, as only image-level annotations are required for training. Current anomaly detection methods mainly rely on generative adversarial networks or…

Image and Video Processing · Electrical Eng. & Systems 2022-10-06 Julia Wolleb , Florentin Bieder , Robin Sandkühler , Philippe C. Cattin

Anomaly detection in medical imaging plays a crucial role in identifying pathological regions across various imaging modalities, such as brain MRI, liver CT, and carotid ultrasound (US). However, training fully supervised segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Yuan Bi , Lucie Huang , Ricarda Clarenbach , Reza Ghotbi , Angelos Karlas , Nassir Navab , Zhongliang Jiang

The quality of patient care associated with diagnostic radiology is proportionate to a physician workload. Segmentation is a fundamental limiting precursor to both diagnostic and therapeutic procedures. Advances in machine learning (ML) aim…

Image and Video Processing · Electrical Eng. & Systems 2022-08-30 Ahmed Ghorbel , Ahmed Aldahdooh , Shadi Albarqouni , Wassim Hamidouche

Lesion detection in brain Magnetic Resonance Images (MRIs) remains a challenging task. MRIs are typically read and interpreted by domain experts, which is a tedious and time-consuming process. Recently, unsupervised anomaly detection (UAD)…

Image and Video Processing · Electrical Eng. & Systems 2022-02-01 Marcel Bengs , Finn Behrendt , Max-Heinrich Laves , Julia Krüger , Roland Opfer , Alexander Schlaefer

Brain cancer can be very fatal, but chances of survival increase through early detection and treatment. Doctors use Magnetic Resonance Imaging (MRI) to detect and locate tumors in the brain, and very carefully analyze scans to segment brain…

Computer Vision and Pattern Recognition · Computer Science 2018-11-08 Ryan Sherman

Segmentation of structural and diffusion MRI (sMRI/dMRI) is usually performed independently in neuroimaging pipelines. However, some brain structures (e.g., globus pallidus, thalamus and its nuclei) can be extracted more accurately by…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Juan Eugenio Iglesias , Koen Van Leemput , Polina Golland , Anastasia Yendiki

Brain tumor segmentation is a fundamental step in assessing a patient's cancer progression. However, manual segmentation demands significant expert time to identify tumors in 3D multimodal brain MRI scans accurately. This reliance on manual…

Image and Video Processing · Electrical Eng. & Systems 2024-05-07 Fadillah Maani , Anees Ur Rehman Hashmi , Numan Saeed , Mohammad Yaqub

Tumor volume segmentation on MRI is a challenging and time-consuming process that is performed manually in typical clinical settings. This work presents an approach to automated delineation of head and neck tumors on MRI scans, developed in…

Image and Video Processing · Electrical Eng. & Systems 2025-01-10 Andrei Iantsen

To develop a domain-agnostic, semi-supervised anomaly detection framework that integrates deep reinforcement learning (DRL) to address challenges such as large-scale data, overfitting, and class imbalance, focusing on brain MRI volumes.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Zeduo Zhang , Yalda Mohsenzadeh

The availability of large scale data with high quality ground truth labels is a challenge when developing supervised machine learning solutions for healthcare domain. Although, the amount of digital data in clinical workflows is increasing,…

Image and Video Processing · Electrical Eng. & Systems 2022-08-31 Sara Atito , Syed Muhammad Anwar , Muhammad Awais , Josef Kitler

Artificial intelligence is increasingly integrated into radiotherapy workflows, yet such pipelines remain vulnerable to out-of-distribution image data that may introduce unexpected behavior in clinical tasks. Deep learning-based anomaly…

In medical vision, different imaging modalities provide complementary information. However, in practice, not all modalities may be available during inference or even training. Previous approaches, e.g., knowledge distillation or image…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Aishik Konwer , Xiaoling Hu , Joseph Bae , Xuan Xu , Chao Chen , Prateek Prasanna

Computer-aided segmentation of brain tumors from MRI data is of crucial significance to clinical decision-making in diagnosis, treatment planning, and follow-up disease monitoring. Gliomas, owing to their high malignancy and heterogeneity,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 MD Rashidul Islam , Bakary Gibba

Anomaly detection (AD) is the identification of data samples that do not fit a learned data distribution. As such, AD systems can help physicians to determine the presence, severity, and extension of a pathology. Deep generative models,…

Image and Video Processing · Electrical Eng. & Systems 2021-04-12 Jaime Simarro , Ezequiel de la Rosa , Thijs Vande Vyvere , David Robben , Diana M. Sima

Deep sparse auto-encoders with mixed structure regularization (MSR) in addition to explicit sparsity regularization term and stochastic corruption of the input data with Gaussian noise have the potential to improve unsupervised abnormality…

Computer Vision and Pattern Recognition · Computer Science 2019-03-05 Moti Freiman , Ravindra Manjeshwar , Liran Goshen

Medical anomaly detection is a crucial yet challenging task aimed at recognizing abnormal images to assist in diagnosis. Due to the high-cost annotations of abnormal images, most methods utilize only known normal images during training and…

Computer Vision and Pattern Recognition · Computer Science 2023-03-21 Yu Cai , Hao Chen , Xin Yang , Yu Zhou , Kwang-Ting Cheng

Diagnosis and treatment guidance are aided by detecting relevant biomarkers in medical images. Although supervised deep learning can perform accurate segmentation of pathological areas, it is limited by requiring a-priori definitions of…

Prostate cancer is one of the most prevalent malignancies in the world. While deep learning has potential to further improve computer-aided prostate cancer detection on MRI, its efficacy hinges on the exhaustive curation of manually…

Computer Vision and Pattern Recognition · Computer Science 2024-06-19 Alex Chen , Nathan Lay , Stephanie Harmon , Kutsev Ozyoruk , Enis Yilmaz , Brad J. Wood , Peter A. Pinto , Peter L. Choyke , Baris Turkbey