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In this paper we consider the problem of unsupervised anomaly segmentation in medical images, which has attracted increasing attention in recent years due to the expensive pixel-level annotations from experts and the existence of a large…

Image and Video Processing · Electrical Eng. & Systems 2021-12-20 Raunak Dey , Wenbo Sun , Haibo Xu , Yi Hong

The complex heterogeneity of brain tumours is increasingly recognized to demand data of magnitudes and richness only fully-inclusive, large-scale collections drawn from routine clinical care could plausibly offer. This is a task…

Computer Vision and Pattern Recognition · Computer Science 2023-05-01 James K Ruffle , Samia Mohinta , Robert J Gray , Harpreet Hyare , Parashkev Nachev

Deep unsupervised anomaly detection in brain magnetic resonance imaging offers a promising route to identify pathological deviations without requiring lesion-specific annotations. Yet, fragmented evaluations, heterogeneous datasets, and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Alexander Frotscher , Christian F. Baumgartner , Thomas Wolfers

Tumors can manifest in various forms and in different areas of the human body. Brain tumors are specifically hard to diagnose and treat because of the complexity of the organ in which they develop. Detecting them in time can lower the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-18 Antonio Curci , Andrea Esposito

Brain tumors are one of the deadliest forms of cancer with a mortality rate of over 80%. A quick and accurate diagnosis is crucial to increase the chance of survival. However, in medical analysis, the manual annotation and segmentation of a…

Image and Video Processing · Electrical Eng. & Systems 2024-03-18 Zachary Schwehr , Sriman Achanta

Detection of various lesions in brain MRI is clinically critical, but challenging due to the diversity of lesions and variability in imaging conditions. Current unsupervised learning methods detect anomalies mainly through reconstructing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Tao Yang , Xiuying Wang , Hao Liu , Guanzhong Gong , Lian-Ming Wu , Yu-Ping Wang , Lisheng Wang

The use of supervised deep learning techniques to detect pathologies in brain MRI scans can be challenging due to the diversity of brain anatomy and the need for annotated data sets. An alternative approach is to use unsupervised anomaly…

Image and Video Processing · Electrical Eng. & Systems 2023-03-08 Finn Behrendt , Debayan Bhattacharya , Julia Krüger , Roland Opfer , Alexander Schlaefer

Expert interpretation of anatomical images of the human brain is the central part of neuro-radiology. Several machine learning-based techniques have been proposed to assist in the analysis process. However, the ML models typically need to…

Deep unsupervised representation learning has recently led to new approaches in the field of Unsupervised Anomaly Detection (UAD) in brain MRI. The main principle behind these works is to learn a model of normal anatomy by learning to…

Image and Video Processing · Electrical Eng. & Systems 2020-04-09 Christoph Baur , Stefan Denner , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab

In medical imaging, anomaly detection is a vital element of healthcare diagnostics, especially for neurological conditions which can be life-threatening. Conventional deterministic methods often fall short when it comes to capturing the…

Machine Learning · Computer Science 2025-04-23 Dip Roy

Automatic segmentation of brain abnormalities is challenging, as they vary considerably from one pathology to another. Current methods are supervised and require numerous annotated images for each pathology, a strenuous task. To tackle…

Image and Video Processing · Electrical Eng. & Systems 2021-01-27 Benjamin Lambert , Maxime Louis , Senan Doyle , Florence Forbes , Michel Dojat , Alan Tucholka

Many successful methods developed for medical image analysis that are based on machine learning use supervised learning approaches, which often require large datasets annotated by experts to achieve high accuracy. However, medical data…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Banafshe Felfeliyan , Abhilash Hareendranathan , Gregor Kuntze , David Cornell , Nils D. Forkert , Jacob L. Jaremko , Janet L. Ronsky

Pathological anomalies exhibit diverse appearances in medical imaging, making it difficult to collect and annotate a representative amount of data required to train deep learning models in a supervised setting. Therefore, in this work, we…

Image and Video Processing · Electrical Eng. & Systems 2023-07-18 Mariana-Iuliana Georgescu

Lesion detection in brain Magnetic Resonance Images (MRI) remains a challenging task. State-of-the-art approaches are mostly based on supervised learning making use of large annotated datasets. Human beings, on the other hand, even…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Xiaoran Chen , Ender Konukoglu

Automatic image segmentation becomes very crucial for tumor detection in medical image processing.In general, manual and semi automatic segmentation techniques require more time and knowledge. However these drawbacks had overcome by…

Computer Vision and Pattern Recognition · Computer Science 2016-03-09 D. Anithadevi , K. Perumal

Supervised deep learning techniques show promise in medical image analysis. However, they require comprehensive annotated data sets, which poses challenges, particularly for rare diseases. Consequently, unsupervised anomaly detection (UAD)…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Finn Behrendt , Debayan Bhattacharya , Lennart Maack , Julia Krüger , Roland Opfer , Robin Mieling , Alexander Schlaefer

The scarcity of labeled data often limits the application of supervised deep learning techniques for medical image segmentation. This has motivated the development of semi-supervised techniques that learn from a mixture of labeled and…

Computer Vision and Pattern Recognition · Computer Science 2019-11-05 Gerda Bortsova , Florian Dubost , Laurens Hogeweg , Ioannis Katramados , Marleen de Bruijne

Semi-supervised learning relaxes the need of large pixel-wise labeled datasets for image segmentation by leveraging unlabeled data. A prominent way to exploit unlabeled data is to regularize model predictions. Since the predictions of…

Computer Vision and Pattern Recognition · Computer Science 2023-10-26 Sukesh Adiga , Jose Dolz , Herve Lombaert

Artificial intelligence aids in brain tumor detection via MRI scans, enhancing the accuracy and reducing the workload of medical professionals. However, in scenarios with extremely limited medical images, traditional deep learning…

Computer Vision and Pattern Recognition · Computer Science 2024-10-16 Sin Chee Chin , Xuan Zhang , Lee Yeong Khang , Wenming Yang

Purpose: Lesion segmentation in medical imaging is key to evaluating treatment response. We have recently shown that reinforcement learning can be applied to radiological images for lesion localization. Furthermore, we demonstrated that…

Computer Vision and Pattern Recognition · Computer Science 2021-03-22 Joseph Stember , Hrithwik Shalu