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Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

Histology images with multi-gigapixel of resolution yield rich information for cancer diagnosis and prognosis. Most of the time, only slide-level label is available because pixel-wise annotation is labour intensive task. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2022-09-08 Made Satria Wibawa , Kwok-Wai Lo , Lawrence Young , Nasir Rajpoot

Breast cancer is one of the most serious types of cancer that can occur in women. The automatic diagnosis of breast cancer by analyzing histological images (HIs) is important for patients and their prognosis. The classification of HIs…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Hayder A. Khikani , Naira Elazab , Ahmed Elgarayhi , Mohammed Elmogy , Mohammed Sallah

Breast cancer is one of the leading causes of female mortality in the world. This can be reduced when diagnoses are performed at the early stages of progression. Further, the efficiency of the process can be significantly improved with…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Aravind Ravi

Convolutional Neural Networks (CNN) are state-of-the-art models for many image classification tasks. However, to recognize cancer subtypes automatically, training a CNN on gigapixel resolution Whole Slide Tissue Images (WSI) is currently…

Computer Vision and Pattern Recognition · Computer Science 2016-03-10 Le Hou , Dimitris Samaras , Tahsin M. Kurc , Yi Gao , James E. Davis , Joel H. Saltz

Fine-grained classification is challenging because categories can only be discriminated by subtle and local differences. Variances in the pose, scale or rotation usually make the problem more difficult. Most fine-grained classification…

Computer Vision and Pattern Recognition · Computer Science 2014-11-25 Tianjun Xiao , Yichong Xu , Kuiyuan Yang , Jiaxing Zhang , Yuxin Peng , Zheng Zhang

Although CNNs are widely considered as the state-of-the-art models in various applications of image analysis, one of the main challenges still open is the training of a CNN on high resolution images. Different strategies have been proposed…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Nadia Brancati , Giuseppe De Pietro , Daniel Riccio , Maria Frucci

Undoubtedly breast cancer identifies itself as one of the most widespread and terrifying cancers across the globe. Millions of women are getting affected each year from it. Breast cancer remains the major one for being the reason of largest…

Image and Video Processing · Electrical Eng. & Systems 2024-03-28 Sheekar Banerjee , Md. Kamrul Hasan Monir

Histopathology image analysis can be considered as a Multiple instance learning (MIL) problem, where the whole slide histopathology image (WSI) is regarded as a bag of instances (i.e, patches) and the task is to predict a single class label…

Computer Vision and Pattern Recognition · Computer Science 2019-06-28 Meng Li , Lin Wu , Arnold Wiliem , Kun Zhao , Teng Zhang , Brian C. Lovell

Accurate medical image segmentation is essential for diagnosis and treatment planning of diseases. Convolutional Neural Networks (CNNs) have achieved state-of-the-art performance for automatic medical image segmentation. However, they are…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Ran Gu , Guotai Wang , Tao Song , Rui Huang , Michael Aertsen , Jan Deprest , Sébastien Ourselin , Tom Vercauteren , Shaoting Zhang

Intracranial hemorrhage (ICH) is a life-threatening medical emergency that requires timely and accurate diagnosis for effective treatment and improved patient survival rates. While deep learning techniques have emerged as the leading…

Computer Vision and Pattern Recognition · Computer Science 2023-08-30 Amirhossein Rasoulian , Soorena Salari , Yiming Xiao

In this paper, we develop a complete pipeline for stain normalization, segmentation, and classification of nuclei in hematoxylin and eosin (H&E) stained breast cancer histopathology images. In the first step, we use a CNN-based stain…

Computer Vision and Pattern Recognition · Computer Science 2018-11-12 Edwin Yuan , Junkyo Suh

Cervical Cancer continues to be the leading gynecological malignancy, posing a persistent threat to women's health on a global scale. Early screening via cytology Whole Slide Image (WSI) diagnosis is critical to prevent this Cancer…

Computer Vision and Pattern Recognition · Computer Science 2024-07-30 Honglin Li , Yusuan Sun , Chenglu Zhu , Yunlong Zhang , Shichuan Zhang , Zhongyi Shui , Pingyi Chen , Jingxiong Li , Sunyi Zheng , Can Cui , Lin Yang

Cervical cancer is one of the most common types of cancer found in females. It contributes to 6-29% of all cancers in women. It is caused by the Human Papilloma Virus (HPV). The 5-year survival chances of cervical cancer range from 17%-92%…

Image and Video Processing · Electrical Eng. & Systems 2022-09-27 Tamanna Sood

Incorporating human domain knowledge for breast tumor diagnosis is challenging, since shape, boundary, curvature, intensity, or other common medical priors vary significantly across patients and cannot be employed. This work proposes a new…

Image and Video Processing · Electrical Eng. & Systems 2020-09-03 Aleksandar Vakanski , Min Xian , Phoebe Freer

Background: Renal chronicity indices (CI) have been identified as strong predictors of long-term outcomes in lupus nephritis (LN) patients. However, assessment by pathologists is hindered by challenges such as substantial time requirements,…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Tianqi Tu , Hui Wang , Jiangbo Pei , Xiaojuan Yu , Aidong Men , Suxia Wang , Qingchao Chen , Ying Tan , Feng Yu , Minghui Zhao

Due to the lack of fine-grained annotation guidance, current Multiple Instance Learning (MIL) struggles to establish a robust causal relationship between Whole Slide Image (WSI) diagnosis and evidence sub-images, just like fully supervised…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Tianhang Nan , Yong Ding , Hao Quan , Deliang Li , Lisha Li , Guanghong Zhao , Xiaoyu Cui

Ovarian cancer remains one of the most lethal gynecological malignancies, largely due to late diagnosis and extensive heterogeneity across subtypes. Current diagnostic methods are limited in their ability to reveal underlying genomic…

Image and Video Processing · Electrical Eng. & Systems 2025-11-06 Gabriela Fernandes

Ovarian cancer remains a challenging malignancy to diagnose and manage, with prognosis heavily dependent on the stage at detection. Accurate grading and staging, primarily based on histopathological examination of biopsy tissue samples, are…

Medical Physics · Physics 2025-05-16 Ashmit K Mishra , Mousa Alrubayan , Prabhakar Pradhan

Cervical cancer remains a significant health challenge, with high incidence and mortality rates, particularly in transitioning countries. Conventional Liquid-Based Cytology(LBC) is a labor-intensive process, requires expert pathologists and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-30 Love Panta , Suraj Prasai , Karishma Malla Vaidya , Shyam Shrestha , Suresh Manandhar