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Separating and labeling each instance of a nucleus (instance-aware segmentation) is the key challenge in segmenting single cell nuclei on fluorescence microscopy images. Deep Neural Networks can learn the implicit transformation of a…

Computer Vision and Pattern Recognition · Computer Science 2021-08-11 Florian Kromp , Lukas Fischer , Eva Bozsaky , Inge Ambros , Wolfgang Doerr , Sabine Taschner-Mandl , Peter Ambros , Allan Hanbury

Intra-operative ultrasound is an increasingly important imaging modality in neurosurgery. However, manual interaction with imaging data during the procedures, for example to select landmarks or perform segmentation, is difficult and can be…

Computer Vision and Pattern Recognition · Computer Science 2019-04-19 Julia Rackerseder , Rüdiger Göbl , Nassir Navab , Christoph Hennersperger

We propose an embarrassingly simple point annotation scheme to collect weak supervision for instance segmentation. In addition to bounding boxes, we collect binary labels for a set of points uniformly sampled inside each bounding box. We…

Computer Vision and Pattern Recognition · Computer Science 2022-06-17 Bowen Cheng , Omkar Parkhi , Alexander Kirillov

Quantitative analysis of cell nuclei in microscopic images is an essential yet challenging source of biological and pathological information. The major challenge is accurate detection and segmentation of densely packed nuclei in images…

Quantitative Methods · Quantitative Biology 2019-11-14 Linqing Feng , Jun Ho Song , Jiwon Kim , Soomin Jeong , Jin Sung Park , Jinhyun Kim

We present a weakly supervised instance segmentation algorithm based on deep community learning with multiple tasks. This task is formulated as a combination of weakly supervised object detection and semantic segmentation, where individual…

Computer Vision and Pattern Recognition · Computer Science 2020-11-19 Jaedong Hwang , Seohyun Kim , Jeany Son , Bohyung Han

Separating overlapped nuclei is a major challenge in histopathology image analysis. Recently published approaches have achieved promising overall performance on nuclei segmentation; however, their performance on separating overlapped nuclei…

Image and Video Processing · Electrical Eng. & Systems 2021-10-01 Haotian Wang , Aleksandar Vakanski , Changfa Shi , Min Xian

Large-scale datasets with point-wise semantic and instance labels are crucial to 3D instance segmentation but also expensive. To leverage unlabeled data, previous semi-supervised 3D instance segmentation approaches have explored…

Computer Vision and Pattern Recognition · Computer Science 2024-06-25 Yizheng Wu , Zhiyu Pan , Kewei Wang , Xingyi Li , Jiahao Cui , Liwen Xiao , Guosheng Lin , Zhiguo Cao

Food instance segmentation is essential to estimate the serving size of dishes in a food image. The recent cutting-edge techniques for instance segmentation are deep learning networks with impressive segmentation quality and fast…

Computer Vision and Pattern Recognition · Computer Science 2023-06-29 Huu-Thanh Nguyen , Yu Cao , Chong-Wah Ngo , Wing-Kwong Chan

Instance segmentation is the problem of detecting and delineating each distinct object of interest appearing in an image. Current instance segmentation approaches consist of ensembles of modules that are trained independently of each other,…

Computer Vision and Pattern Recognition · Computer Science 2016-10-26 Bernardino Romera-Paredes , Philip H. S. Torr

While convolutional neural networks have gained impressive success recently in solving structured prediction problems such as semantic segmentation, it remains a challenge to differentiate individual object instances in the scene. Instance…

Machine Learning · Computer Science 2017-07-14 Mengye Ren , Richard S. Zemel

This paper addresses the task of nuclei segmentation in high-resolution histopathological images. We propose an auto- matic end-to-end deep neural network algorithm for segmenta- tion of individual nuclei. A nucleus-boundary model is…

Computer Vision and Pattern Recognition · Computer Science 2020-03-18 Yuxin Cui , Guiying Zhang , Zhonghao Liu , Zheng Xiong , Jianjun Hu

Image segmentation is a fundamental problem in biomedical image analysis. Recent advances in deep learning have achieved promising results on many biomedical image segmentation benchmarks. However, due to large variations in biomedical…

Computer Vision and Pattern Recognition · Computer Science 2017-06-16 Lin Yang , Yizhe Zhang , Jianxu Chen , Siyuan Zhang , Danny Z. Chen

Instance segmentation is essential for numerous computer vision applications, including robotics, human-computer interaction, and autonomous driving. Currently, popular models bring impressive performance in instance segmentation by…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Cuong Manh Hoang

Accurate and automated tumor segmentation is highly desired since it has the great potential to increase the efficiency and reproducibility of computing more complete tumor measurements and imaging biomarkers, comparing to (often partial)…

Image and Video Processing · Electrical Eng. & Systems 2020-08-26 Ling Zhang , Yu Shi , Jiawen Yao , Yun Bian , Kai Cao , Dakai Jin , Jing Xiao , Le Lu

Annotation cost is a bottleneck for collecting massive data in mammography, especially for training deep neural networks. In this paper, we study the use of heterogeneous levels of annotation granularity to improve predictive performances.…

Image and Video Processing · Electrical Eng. & Systems 2019-09-13 Thi-Lam-Thuy Le , Nicolas Thome , Sylvain Bernard , Vincent Bismuth , Fanny Patoureaux

Deep convolutional neural networks (CNNs) are state-of-the-art for semantic image segmentation, but typically require many labeled training samples. Obtaining 3D segmentations of medical images for supervised training is difficult and labor…

Computer Vision and Pattern Recognition · Computer Science 2019-07-29 Zhenlin Xu , Marc Niethammer

Semi-supervised segmentation methods have demonstrated promising results in natural scenarios, providing a solution to reduce dependency on manual annotation. However, these methods face significant challenges when directly applied to…

Computer Vision and Pattern Recognition · Computer Science 2024-02-08 Ye Zhang , Ziyue Wang , Yifeng Wang , Hao Bian , Linghan Cai , Hengrui Li , Lingbo Zhang , Yongbing Zhang

Many successful methods developed for medical image analysis that are based on machine learning use supervised learning approaches, which often require large datasets annotated by experts to achieve high accuracy. However, medical data…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Banafshe Felfeliyan , Abhilash Hareendranathan , Gregor Kuntze , David Cornell , Nils D. Forkert , Jacob L. Jaremko , Janet L. Ronsky

Nucleus instance segmentation in histology images is crucial for a broad spectrum of clinical applications. Current dominant algorithms rely on regression of nuclear proxy maps. Distinguishing nucleus instances from the estimated maps…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Zhongyi Shui , Yunlong Zhang , Kai Yao , Chenglu Zhu , Sunyi Zheng , Jingxiong Li , Honglin Li , Yuxuan Sun , Ruizhe Guo , Lin Yang

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha