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Prognostic models aim to predict the future course of a disease or condition and are a vital component of personalized medicine. Statistical models make use of longitudinal data to capture the temporal aspect of disease progression;…

Machine Learning · Computer Science 2020-07-13 Joshua Bridge , Simon P. Harding , Yalin Zheng

Diabetes is a globally prevalent disease that can cause visible microvascular complications such as diabetic retinopathy and macular edema in the human eye retina, the images of which are today used for manual disease screening. This…

Image and Video Processing · Electrical Eng. & Systems 2019-04-19 Jaakko Sahlsten , Joel Jaskari , Jyri Kivinen , Lauri Turunen , Esa Jaanio , Kustaa Hietala , Kimmo Kaski

Retinal diseases remain among the leading preventable causes of visual impairment worldwide. Automated screening based on fundus image analysis has the potential to expand access to early detection, particularly in underserved populations.…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Ali Akram

Early detection of retinal diseases is one of the most important means of preventing partial or permanent blindness in patients. In this research, a novel multi-label classification system is proposed for the detection of multiple retinal…

Computer Vision and Pattern Recognition · Computer Science 2022-08-01 M. A. Rodriguez , H. AlMarzouqi , P. Liatsis

Retinal vessel segmentation is a fundamental step in screening, diagnosis, and treatment of various cardiovascular and ophthalmic diseases. Robustness is one of the most critical requirements for practical utilization, since the test images…

Image and Video Processing · Electrical Eng. & Systems 2021-09-29 Xu Sun , Huihui Fang , Yehui Yang , Dongwei Zhu , Lei Wang , Junwei Liu , Yanwu Xu

Interpretability of deep learning (DL) systems is gaining attention in medical imaging to increase experts' trust in the obtained predictions and facilitate their integration in clinical settings. We propose a deep visualization method to…

Computer Vision and Pattern Recognition · Computer Science 2022-02-02 Cristina González-Gonzalo , Bart Liefers , Bram van Ginneken , Clara I. Sánchez

High-quality fundus images provide essential anatomical information for clinical screening and ophthalmic disease diagnosis. Yet, due to hardware limitations, operational variability, and patient compliance, fundus images often suffer from…

Federated learning (FL) enables the collaborative training of deep neural networks across decentralized data archives (i.e., clients) without sharing the local data of the clients. Most of the existing FL methods assume that the data…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Barış Büyüktaş , Gencer Sumbul , Begüm Demir

Deep learning-based segmentation methods have been widely employed for automatic glaucoma diagnosis and prognosis. In practice, fundus images obtained by different fundus cameras vary significantly in terms of illumination and intensity.…

Computer Vision and Pattern Recognition · Computer Science 2022-10-11 Qianbi Yu , Dongnan Liu , Chaoyi Zhang , Xinwen Zhang , Weidong Cai

End-to-end training from scratch of current deep architectures for new computer vision problems would require Imagenet-scale datasets, and this is not always possible. In this paper we present a method that is able to take advantage of…

Computer Vision and Pattern Recognition · Computer Science 2017-05-25 Lluis Gomez , Yash Patel , Marçal Rusiñol , Dimosthenis Karatzas , C. V. Jawahar

Introspection of deep supervised predictive models trained on functional and structural brain imaging may uncover novel markers of Alzheimer's disease (AD). However, supervised training is prone to learning from spurious features (shortcut…

Machine Learning · Computer Science 2022-05-24 Alex Fedorov , Lei Wu , Tristan Sylvain , Margaux Luck , Thomas P. DeRamus , Dmitry Bleklov , Sergey M. Plis , Vince D. Calhoun

Diabetic retinopathy (DR) grading from fundus images has attracted increasing interest in both academic and industrial communities. Most convolutional neural network (CNN) based algorithms treat DR grading as a classification task via…

Computer Vision and Pattern Recognition · Computer Science 2021-03-19 Yehui Yang , Fangxin Shang , Binghong Wu , Dalu Yang , Lei Wang , Yanwu Xu , Wensheng Zhang , Tianzhu Zhang

Retinal foundation models have significantly advanced retinal image analysis by leveraging self-supervised learning to reduce dependence on labeled data while achieving strong generalization. Many recent approaches enhance retinal image…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Yeonkyung Lee , Woojung Han , Youngjun Jun , Hyeonmin Kim , Jungkyung Cho , Seong Jae Hwang

The diabetic retinopathy is timely diagonalized through color eye fundus images by experienced ophthalmologists, in order to recognize potential retinal features and identify early-blindness cases. In this paper, it is proposed to extract…

Computer Vision and Pattern Recognition · Computer Science 2017-07-31 Ibrahim Sadek , Mohamed Elawady , Abd El Rahman Shabayek

Manually annotating medical images is extremely expensive, especially for large-scale datasets. Self-supervised contrastive learning has been explored to learn feature representations from unlabeled images. However, unlike natural images,…

Computer Vision and Pattern Recognition · Computer Science 2021-07-20 Yijin Huang , Li Lin , Pujin Cheng , Junyan Lyu , Xiaoying Tang

Purpose To develop a computer based method for the automated assessment of image quality in the context of diabetic retinopathy (DR) to guide the photographer. Methods A deep learning framework was trained to grade the images automatically.…

Computer Vision and Pattern Recognition · Computer Science 2017-03-08 Sajib Kumar Saha , Basura Fernando , Jorge Cuadros , Di Xiao , Yogesan Kanagasingam

The success of supervised learning requires large-scale ground truth labels which are very expensive, time-consuming, or may need special skills to annotate. To address this issue, many self- or un-supervised methods are developed. Unlike…

Computer Vision and Pattern Recognition · Computer Science 2020-04-14 Longlong Jing , Yucheng Chen , Ling Zhang , Mingyi He , Yingli Tian

In this paper, a method is presented for superimposition (i.e. registration) of eye fundus images from persons with diabetes screened over many years for diabetic retinopathy. The method is fully automatic and robust to camera changes and…

Computer Vision and Pattern Recognition · Computer Science 2018-11-28 Guillaume Noyel , Rebecca Thomas , Gavin Bhakta , Andrew Crowder , David Owens , Peter Boyle

This paper introduces an innovative software system for fundus image analysis that deliberately diverges from the conventional screening approach, opting not to predict specific diagnoses. Instead, our methodology mimics the diagnostic…

Computer Vision and Pattern Recognition · Computer Science 2025-01-27 Dmitry Ryabtsev , Boris Vasilyev , Sergey Shershakov

In ophthalmology, early fundus screening is an economic and effective way to prevent blindness caused by ophthalmic diseases. Clinically, due to the lack of medical resources, manual diagnosis is time-consuming and may delay the condition.…

Computer Vision and Pattern Recognition · Computer Science 2021-02-17 Ning Li , Tao Li , Chunyu Hu , Kai Wang , Hong Kang