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Cell detection, segmentation and classification are essential for analyzing tumor microenvironments (TME) on hematoxylin and eosin (H&E) slides. Existing methods suffer from poor performance on understudied cell types (rare or not present…

Supervised image segmentation assigns image voxels to a set of labels, as defined by a specific labeling protocol. In this paper, we decompose segmentation into two steps. The first step is what we call "primitive segmentation", where…

Image and Video Processing · Electrical Eng. & Systems 2018-09-07 Sundaresh Ram , Mert R. Sabuncu

We propose a novel approach for automatic extraction (instance segmentation) of fibers from low resolution 3D X-ray computed tomography scans of short glass fiber reinforced polymers. We have designed a 3D instance segmentation architecture…

Computer Vision and Pattern Recognition · Computer Science 2019-01-07 Tomasz Konopczyński , Thorben Kröger , Lei Zheng , Jürgen Hesser

We share our recent findings in an attempt to train a universal segmentation network for various cell types and imaging modalities. Our method was built on the generalized U-Net architecture, which allows the evaluation of each component…

Computer Vision and Pattern Recognition · Computer Science 2022-08-01 Tianqi Guo , Yin Wang , Luis Solorio , Jan P. Allebach

In this paper, we study weakly-supervised laparoscopic image segmentation with sparse annotations. We introduce a novel Bayesian deep learning approach designed to enhance both the accuracy and interpretability of the model's segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-14 Zhou Zheng , Yuichiro Hayashi , Masahiro Oda , Takayuki Kitasaka , Kensaku Mori

In this work, we present a new operator, called Instance Mask Projection (IMP), which projects a predicted Instance Segmentation as a new feature for semantic segmentation. It also supports back propagation so is trainable end-to-end. Our…

Computer Vision and Pattern Recognition · Computer Science 2019-06-18 Cheng-Yang Fu , Tamara L. Berg , Alexander C. Berg

The accurate segmentation and tracking of cells in microscopy image sequences is an important task in biomedical research, e.g., for studying the development of tissues, organs or entire organisms. However, the segmentation of touching…

Computer Vision and Pattern Recognition · Computer Science 2020-12-10 Tim Scherr , Katharina Löffler , Moritz Böhland , Ralf Mikut

This work proposes a novel approach beyond supervised learning for effective pathological image analysis, addressing the challenge of limited robust labeled data. Pathological diagnosis of diseases like cancer has conventionally relied on…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Joonhyeon Song , Seohwan Yun , Seongho Yoon , Joohyeok Kim , Sangmin Lee

The goal of this paper is to present a new efficient image segmentation method based on evolutionary computation which is a model inspired from human behavior. Based on this model, a four layer process for image segmentation is proposed…

Computer Vision and Pattern Recognition · Computer Science 2017-12-07 Roohollah Aslanzadeh , Kazem Qazanfari , Mohammad Rahmati

We propose EM-PASTE: an Expectation Maximization(EM) guided Cut-Paste compositional dataset augmentation approach for weakly-supervised instance segmentation using only image-level supervision. The proposed method consists of three main…

Computer Vision and Pattern Recognition · Computer Science 2022-12-16 Yunhao Ge , Jiashu Xu , Brian Nlong Zhao , Laurent Itti , Vibhav Vineet

This paper presents a novel approach for learning instance segmentation with image-level class labels as supervision. Our approach generates pseudo instance segmentation labels of training images, which are used to train a fully supervised…

Computer Vision and Pattern Recognition · Computer Science 2019-05-13 Jiwoon Ahn , Sunghyun Cho , Suha Kwak

Highly clumped nuclei clusters captured in fluorescence in situ hybridization microscopy images are common histology entities under investigations in a wide spectrum of tissue-related biomedical investigations. Due to their large scale in…

Computer Vision and Pattern Recognition · Computer Science 2018-08-15 Xiaoyuan Guo , Hanyi Yu , Blair Rossetti , George Teodoro , Daniel Brat , Jun Kong

Nuclei detection and segmentation in hematoxylin and eosin-stained (H&E) tissue images are important clinical tasks and crucial for a wide range of applications. However, it is a challenging task due to nuclei variances in staining and…

Image and Video Processing · Electrical Eng. & Systems 2023-10-09 Fabian Hörst , Moritz Rempe , Lukas Heine , Constantin Seibold , Julius Keyl , Giulia Baldini , Selma Ugurel , Jens Siveke , Barbara Grünwald , Jan Egger , Jens Kleesiek

We address the problem of automated nuclear segmentation, classification, and quantification from Haematoxylin and Eosin stained histology images, which is of great relevance for several downstream computational pathology applications. In…

Computer Vision and Pattern Recognition · Computer Science 2022-04-19 Lihao Liu , Chenyang Hong , Angelica I. Aviles-Rivero , Carola-Bibiane Schönlieb

The task of Split and Rephrase, which splits a complex sentence into multiple simple sentences with the same meaning, improves readability and enhances the performance of downstream tasks in natural language processing (NLP). However, while…

Computation and Language · Computer Science 2024-04-16 Hayato Tsukagoshi , Tsutomu Hirao , Makoto Morishita , Katsuki Chousa , Ryohei Sasano , Koichi Takeda

Many two-stage instance segmentation heads predict a coarse 28x28 mask per instance, which is insufficient to capture the fine-grained details of many objects. To address this issue, PointRend and RefineMask predict a 112x112 segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-07-06 Cédric Picron , Tinne Tuytelaars

Automated semantic segmentation of cell nuclei in microscopic images is crucial for disease diagnosis and tissue microenvironment analysis. Nonetheless, this task presents challenges due to the complexity and heterogeneity of cells. While…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Zhuchen Shao , Sourya Sengupta , Hua Li , Mark A. Anastasio

Segmentation is a crucial task in the medical imaging field and is often an important primary step or even a prerequisite to the analysis of medical volumes. Yet treatments such as surgery complicate the accurate delineation of regions of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-13 Heejong Kim , Leo Milecki , Mina C Moghadam , Fengbei Liu , Minh Nguyen , Eric Qiu , Abhishek Thanki , Mert R Sabuncu

To minimize the annotation costs associated with the training of semantic segmentation models, researchers have extensively investigated weakly-supervised segmentation approaches. In the current weakly-supervised segmentation methods, the…

Computer Vision and Pattern Recognition · Computer Science 2019-11-13 Wataru Shimoda , Keiji Yanai

Diffusion models suffer from slow sample generation at inference time. Despite recent efforts, improving the sampling efficiency of stochastic samplers for diffusion models remains a promising direction. We propose Splitting Integrators for…

Machine Learning · Computer Science 2024-02-14 Kushagra Pandey , Maja Rudolph , Stephan Mandt