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We consider the estimation of average treatment effects in observational studies and propose a new framework of robust causal inference with unobserved confounders. Our approach is based on distributionally robust optimization and proceeds…

Methodology · Statistics 2023-02-06 Dimitris Bertsimas , Kosuke Imai , Michael Lingzhi Li

In this work, we propose an approach for assessing sensitivity to unobserved confounding in studies with multiple outcomes. We demonstrate how prior knowledge unique to the multi-outcome setting can be leveraged to strengthen causal…

Methodology · Statistics 2023-01-26 Jiajing Zheng , Jiaxi Wu , Alexander D'Amour , Alexander Franks

Most research designing novel predictive models, or employing existing ones, assumes that training and testing data are independent and identically distributed. In practice, the data encountered at serving time often deviate from the…

Machine Learning · Computer Science 2026-03-30 Hanyu Duan , Yi Yang , Ahmed Abbasi , Kar Yan Tam

We study the problem of learning personalized decision policies from observational data while accounting for possible unobserved confounding. Previous approaches, which assume unconfoundedness, i.e., that no unobserved confounders affect…

Machine Learning · Computer Science 2019-11-05 Nathan Kallus , Angela Zhou

Domain generalization (DG) aims to learn predictive models that can generalize to unseen domains. Most existing DG approaches focus on learning domain-invariant representations under the assumption of conditional distribution shift (i.e.,…

Machine Learning · Computer Science 2026-02-03 Jewon Yeom , Kyubyung Chae , Hyunggyu Lim , Yoonna Oh , Dongyoon Yang , Taesup Kim

Practitioners often face the challenge of deploying prediction models in new environments with shifted distributions of covariates and responses. With observational data, such shifts are often driven by unobserved confounding, and can in…

Machine Learning · Computer Science 2026-04-02 Kulunu Dharmakeerthi , YoonHaeng Hur , Tengyuan Liang

Domain generalization (DG) aims to learn from multiple source domains a model that can generalize well on unseen target domains. Existing DG methods mainly learn the representations with invariant marginal distribution of the input…

Machine Learning · Computer Science 2023-05-26 Junkun Yuan , Xu Ma , Ruoxuan Xiong , Mingming Gong , Xiangyu Liu , Fei Wu , Lanfen Lin , Kun Kuang

Learning representations that capture the underlying data generating process is a key problem for data efficient and robust use of neural networks. One key property for robustness which the learned representation should capture and which…

Machine Learning · Computer Science 2022-06-24 Mathieu Chevalley , Charlotte Bunne , Andreas Krause , Stefan Bauer

We study a worst-case scenario in generalization: Out-of-domain generalization from a single source. The goal is to learn a robust model from a single source and expect it to generalize over many unknown distributions. This challenging…

Computer Vision and Pattern Recognition · Computer Science 2021-03-16 Fengchun Qiao , Xi Peng

Unsupervised approaches for learning representations invariant to common transformations are used quite often for object recognition. Learning invariances makes models more robust and practical to use in real-world scenarios. Since data…

Machine Learning · Computer Science 2024-02-27 Gauri Gupta , Ritvik Kapila , Keshav Gupta , Ramesh Raskar

A crucial aspect in reliable machine learning is to design a deployable system in generalizing new related but unobserved environments. Domain generalization aims to alleviate such a prediction gap between the observed and unseen…

Machine Learning · Computer Science 2021-06-01 Changjian Shui , Boyu Wang , Christian Gagné

Predictive algorithms inform consequential decisions in settings with selective labels: outcomes are observed only for units selected by past decision makers. This creates an identification problem under unobserved confounding -- when…

Econometrics · Economics 2025-11-07 Ashesh Rambachan , Amanda Coston , Edward Kennedy

We consider the task of out-of-distribution (OOD) generalization, where the distribution shift is due to an unobserved confounder ($Z$) affecting both the covariates ($X$) and the labels ($Y$). This confounding introduces heterogeneity in…

Machine Learning · Computer Science 2025-08-14 Parjanya Prashant , Seyedeh Baharan Khatami , Bruno Ribeiro , Babak Salimi

Causal inference with observational data can be performed under an assumption of no unobserved confounders (unconfoundedness assumption). There is, however, seldom clear subject-matter or empirical evidence for such an assumption. We…

Methodology · Statistics 2023-11-13 Minna Genbäck , Xavier de Luna

Statistical inferences for high-dimensional regression models have been extensively studied for their wide applications ranging from genomics, neuroscience, to economics. However, in practice, there are often potential unmeasured…

Methodology · Statistics 2023-09-12 Jing Ouyang , Kean Ming Tan , Gongjun Xu

We introduce a new predictive mechanism that operates in the presence of hidden confounding across distributionally diverse data sources while ensuring consistent estimation of causal parameters-despite their recognized suboptimality for…

Statistics Theory · Mathematics 2025-04-01 Carlos García Meixide , David Ríos Insua

Unobserved confounding is a fundamental challenge for estimating causal effects. To address unobserved confounding, recent literature has turned to two different approaches -- proxy variables and the use of multiple treatments. The first…

Methodology · Statistics 2026-05-20 Aytijhya Saha , Stephen Bates , Devavrat Shah

Empirical risk minimization often performs poorly when the distribution of the target domain differs from those of source domains. To address such potential distribution shifts, we develop an unsupervised domain adaptation approach that…

Machine Learning · Statistics 2025-03-25 Zhenyu Wang , Peter Bühlmann , Zijian Guo

This paper develops a robust and efficient method for policy learning from observational data in the presence of unobserved confounding, complementing existing instrumental variable (IV) based approaches. We employ the marginal sensitivity…

Econometrics · Economics 2025-07-29 Zequn Jin , Gaoqian Xu , Xi Zheng , Yahong Zhou

Domain generalization aims to learn knowledge invariant across different distributions while semantically meaningful for downstream tasks from multiple source domains, to improve the model's generalization ability on unseen target domains.…

Machine Learning · Computer Science 2021-06-03 Yunqi Wang , Furui Liu , Zhitang Chen , Qing Lian , Shoubo Hu , Jianye Hao , Yik-Chung Wu
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