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Recent developments in single-cell omics technologies have enabled the quantification of molecular profiles in individual cells at an unparalleled resolution. Deep learning, a rapidly evolving sub-field of machine learning, has instilled a…

Genomics · Quantitative Biology 2024-01-17 Manoj M Wagle , Siqu Long , Carissa Chen , Chunlei Liu , Pengyi Yang

Mixture models are often used to identify meaningful subpopulations (i.e., clusters) in observed data such that the subpopulations have a real-world interpretation (e.g., as cell types). However, when used for subpopulation discovery,…

Methodology · Statistics 2024-03-04 Jiawei Li , Jonathan H. Huggins

There has been a large number of studies in interpretable and explainable ML for cybersecurity, in particular, for intrusion detection. Many of these studies have significant amount of overlapping and repeated evaluations and analysis. At…

Cryptography and Security · Computer Science 2024-07-08 Omer Subasi , Johnathan Cree , Joseph Manzano , Elena Peterson

The ability of large language models (LLMs) to interpret visual representations of data is crucial for advancing their application in data analysis and decision-making processes. This paper presents a novel synthetic dataset designed to…

Computation and Language · Computer Science 2024-09-05 Aneta Pawelec , Victoria Sara Wesołowska , Zuzanna Bączek , Piotr Sankowski

Supervised machine learning often operates on the data-driven paradigm, wherein internal model parameters are autonomously optimized to converge predicted outputs with the ground truth, devoid of explicitly programming rules or a priori…

Machine Learning · Computer Science 2024-12-12 Daniel Geissler , Bo Zhou , Mengxi Liu , Paul Lukowicz

AutoClustering methods aim to automate unsupervised learning tasks, including algorithm selection (AS), hyperparameter optimization (HPO), and pipeline synthesis (PS), by often leveraging meta-learning over dataset meta-features. While…

Machine Learning · Computer Science 2026-02-23 Matheus Camilo da Silva , Leonardo Arrighi , Ana Carolina Lorena , Sylvio Barbon Junior

We introduce Matched Machine Learning, a framework that combines the flexibility of machine learning black boxes with the interpretability of matching, a longstanding tool in observational causal inference. Interpretability is paramount in…

Methodology · Statistics 2023-04-05 Marco Morucci , Cynthia Rudin , Alexander Volfovsky

Multimodal Small-to-Medium sized Language Models (MSLMs) have demonstrated strong capabilities in integrating visual and textual information but still face significant limitations in visual comprehension and mathematical reasoning,…

Machine Learning · Computer Science 2026-01-27 Ashutosh Bajpai , Akshat Bhandari , Akshay Nambi , Tanmoy Chakraborty

Deep learning has achieved remarkable success in processing and managing unstructured data. However, its "black box" nature imposes significant limitations, particularly in sensitive application domains. While existing interpretable machine…

Machine Learning · Computer Science 2025-02-11 Wen-Dong Jiang , Chih-Yung Chang , Show-Jane Yen , Diptendu Sinha Roy

As artificial intelligence (AI) systems become increasingly integrated into critical decision-making processes, the need for transparent and interpretable models has become paramount. In this article we present a new ruleset creation method…

Machine Learning · Computer Science 2024-07-30 Mario Parrón Verdasco , Esteban García-Cuesta

In this paper, we present the Draw-and-Understand framework, exploring how to integrate visual prompting understanding capabilities into Multimodal Large Language Models (MLLMs). Visual prompts allow users to interact through multi-modal…

Computer Vision and Pattern Recognition · Computer Science 2025-02-25 Weifeng Lin , Xinyu Wei , Ruichuan An , Peng Gao , Bocheng Zou , Yulin Luo , Siyuan Huang , Shanghang Zhang , Hongsheng Li

Modern machine learning models are opaque, and as a result there is a burgeoning academic subfield on methods that explain these models' behavior. However, what is the precise goal of providing such explanations, and how can we demonstrate…

Machine Learning · Computer Science 2022-12-01 Patrick Fernandes , Marcos Treviso , Danish Pruthi , André F. T. Martins , Graham Neubig

Large Multimodal Models (LMMs), or Vision-Language Models (VLMs), have shown impressive capabilities in a wide range of visual tasks. However, they often struggle with fine-grained visual reasoning, failing to identify domain-specific…

Computer Vision and Pattern Recognition · Computer Science 2025-02-26 Yucheng Shi , Quanzheng Li , Jin Sun , Xiang Li , Ninghao Liu

Interpretable machine learning tackles the important problem that humans cannot understand the behaviors of complex machine learning models and how these models arrive at a particular decision. Although many approaches have been proposed, a…

Machine Learning · Computer Science 2019-05-21 Mengnan Du , Ninghao Liu , Xia Hu

Machine learning (ML) has become a popular tool in the industrial sector as it helps to improve operations, increase efficiency, and reduce costs. However, deploying and managing ML models in production environments can be complex. This is…

Machine learning (ML) is increasingly employed in real-world applications like medicine or economics, thus, potentially affecting large populations. However, ML models often do not perform homogeneously, leading to underperformance or,…

Machine Learning · Computer Science 2025-08-28 Tom Siegl , Kutalmış Coşkun , Bjarne C. Hiller , Amin Mirzaei , Florian Lemmerich , Martin Becker

Deep learning is becoming increasingly adopted in business and industry due to its ability to transform large quantities of data into high-performing models. These models, however, are generally regarded as black boxes, which, in spite of…

Machine Learning · Computer Science 2023-02-21 Stefan Druc , Peter Wooldridge , Adarsh Krishnamurthy , Soumik Sarkar , Aditya Balu

As machine learning algorithms are increasingly applied to high impact yet high risk tasks, such as medical diagnosis or autonomous driving, it is critical that researchers can explain how such algorithms arrived at their predictions. In…

Computer Vision and Pattern Recognition · Computer Science 2021-12-06 Ruth Fong , Andrea Vedaldi

A task of interest in machine learning (ML) is that of ascribing explanations to the predictions made by ML models. Furthermore, in domains deemed high risk, the rigor of explanations is paramount. Indeed, incorrect explanations can and…

Artificial Intelligence · Computer Science 2025-07-11 Mohamed Siala , Jordi Planes , Joao Marques-Silva

Trained on a vast amount of data, Large Language models (LLMs) have achieved unprecedented success and generalization in modeling fairly complex textual inputs in the abstract space, making them powerful tools for zero-shot learning. Such…

Computer Vision and Pattern Recognition · Computer Science 2023-05-19 Shervin Ardeshir