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There is increasing interest in data-driven approaches for recommending optimal treatment strategies in many chronic disease management and critical care applications. Reinforcement learning methods are well-suited to this sequential…

Machine Learning · Computer Science 2023-06-14 Milashini Nambiar , Supriyo Ghosh , Priscilla Ong , Yu En Chan , Yong Mong Bee , Pavitra Krishnaswamy

Causal learning has garnered significant attention in recent years because it reveals the essential relationships that underpin phenomena and delineates the mechanisms by which the world evolves. Nevertheless, traditional causal learning…

Machine Learning · Computer Science 2024-07-31 Zizhen Deng , Xiaolong Zheng , Hu Tian , Daniel Dajun Zeng

Clinical diffusion imaging requires short acquisition times and good image quality to permit its use in various medical applications. In turn, these demands require the development of a robust and efficient post-processing framework in…

Medical Physics · Physics 2015-02-18 Ivan I. Maximov , Farida Grinberg , Irene Neuner , N. Jon Shah

Deep learning has become a prominent computational modeling tool in the areas of computer vision and image processing in recent years. This research comprehensively analyzes the different deep-learning methods used for image-to-image…

Image and Video Processing · Electrical Eng. & Systems 2023-03-17 Yuda Bi

The novelty of new human coronavirus COVID-19/SARS-CoV-2 and the lack of effective drugs and vaccines gave rise to a wide variety of strategies employed to fight this worldwide pandemic. Many of these strategies rely on the repositioning of…

Molecular Networks · Quantitative Biology 2021-06-09 Giulia Fiscon , Federica Conte , Lorenzo Farina , Paola Paci

Objective: Causality mining is an active research area, which requires the application of state-of-the-art natural language processing techniques. In the healthcare domain, medical experts create clinical text to overcome the limitation of…

Causal inference and model interpretability research are gaining increasing attention, especially in the domains of healthcare and bioinformatics. Despite recent successes in this field, decorrelating features under nonlinear environments…

Machine Learning · Computer Science 2022-09-30 Junda Wang , Weijian Li , Han Wang , Hanjia Lyu , Caroline Thirukumaran , Addisu Mesfin , Jiebo Luo

Applying machine learning to real-world medical data, e.g. from hospital archives, has the potential to revolutionize disease detection in brain images. However, detecting pathology in such heterogeneous cohorts is a difficult challenge.…

Image and Video Processing · Electrical Eng. & Systems 2025-08-06 Ana Lawry Aguila , Ayodeji Ijishakin , Juan Eugenio Iglesias , Tomomi Takenaga , Yukihiro Nomura , Takeharu Yoshikawa , Osamu Abe , Shouhei Hanaoka

Clinical trials are a systematic endeavor to assess the safety and efficacy of new drugs or treatments. Conducting such trials typically demands significant financial investment and meticulous planning, highlighting the need for accurate…

Machine Learning · Computer Science 2025-11-03 Tien Huu Do , Antoine Masquelier , Nae Eoun Lee , Jonathan Crowther

Causal inference methods are widely applied in the fields of medicine, policy, and economics. Central to these applications is the estimation of treatment effects to make decisions. Current methods make binary yes-or-no decisions based on…

Machine Learning · Computer Science 2020-04-24 Will Y. Zou , Smitha Shyam , Michael Mui , Mingshi Wang , Jan Pedersen , Zoubin Ghahramani

In this work we present a deep learning approach to conduct hypothesis-free, transcriptomics-based matching of drugs for diseases. Our proposed neural network architecture is trained on approved drug-disease indications, taking as input the…

Genomics · Quantitative Biology 2023-03-22 Yannis Papanikolaou , Francesco Tuveri , Misa Ogura , Daniel O'Donovan

International Classification of Diseases (ICD) are the de facto codes used globally for clinical coding. These codes enable healthcare providers to claim reimbursement and facilitate efficient storage and retrieval of diagnostic…

Computation and Language · Computer Science 2022-02-22 Pavithra Rajendran , Alexandros Zenonos , Josh Spear , Rebecca Pope

Rare diseases represent the long tail of medical imaging, where AI models often fail due to the scarcity of representative training data. In clinical workflows, radiologists frequently consult case reports and literature when confronted…

Computation and Language · Computer Science 2025-11-10 Ha Young Kim , Jun Li , Ana Beatriz Solana , Carolin M. Pirkl , Benedikt Wiestler , Julia A. Schnabel , Cosmin I. Bercea

We introduce OpportunityFinder, a code-less framework for performing a variety of causal inference studies with panel data for non-expert users. In its current state, OpportunityFinder only requires users to provide raw observational data…

Machine Learning · Computer Science 2023-09-26 Huy Nguyen , Prince Grover , Devashish Khatwani

This research addresses the challenge of conducting interpretable causal inference between a binary treatment and its resulting outcome when not all confounders are known. Confounders are factors that have an influence on both the treatment…

Machine Learning · Computer Science 2023-10-24 Sohaib Kiani , Jared Barton , Jon Sushinsky , Lynda Heimbach , Bo Luo

Recommender systems research lacks standardized benchmarks for reproducibility and algorithm comparisons. We introduce RBoard, a novel framework addressing these challenges by providing a comprehensive platform for benchmarking diverse…

Information Retrieval · Computer Science 2024-09-11 Xinyang Shao , Edoardo D'Amico , Gabor Fodor , Tri Kurniawan Wijaya

Estimating individual-level treatment effect from observational data is a fundamental problem in causal inference and has attracted increasing attention in the fields of education, healthcare, and public policy.In this work, we concentrate…

Machine Learning · Computer Science 2025-07-10 Hui Meng , Keping Yang , Xuyu Peng , Bo Zheng

With the development of computer-assisted techniques, research communities including biochemistry and deep learning have been devoted into the drug discovery field for over a decade. Various applications of deep learning have drawn great…

Machine Learning · Computer Science 2023-03-07 Wenhao Hu , Yingying Liu , Xuanyu Chen , Wenhao Chai , Hangyue Chen , Hongwei Wang , Gaoang Wang

The notion of causality assumes a paramount position within the realm of human cognition. Over the past few decades, there has been significant advancement in the domain of causal effect estimation across various disciplines, including but…

Machine Learning · Statistics 2024-05-24 Zongyu Li , Xiaobo Guo , Siwei Qiang

Visual representation learning is ubiquitous in various real-world applications, including visual comprehension, video understanding, multi-modal analysis, human-computer interaction, and urban computing. Due to the emergence of huge…

Computer Vision and Pattern Recognition · Computer Science 2023-03-23 Yang Liu , Yushen Wei , Hong Yan , Guanbin Li , Liang Lin