Related papers: Implementing Stepped Pooled Testing for Rapid COVI…

Background: Rapid testing for an infection is paramount during a pandemic to prevent continued viral spread and excess morbidity and mortality. This study aimed to determine whether alternative testing strategies based on sample pooling can…

COVID-19 has resulted in a global health crisis that may become even more acute over the upcoming months. One of the main reasons behind the current rapid growth of COVID-19 in the U.S. population is the limited availability of testing kits…

Pooled testing offers an efficient solution to the unprecedented testing demands of the COVID-19 pandemic, although with potentially lower sensitivity and increased costs to implementation in some settings. Assessments of this trade-off…

When testing for a disease such as COVID-19, the standard method is individual testing: we take a sample from each individual and test these samples separately. An alternative is pooled testing (or "group testing"), where samples are mixed…

Sample pooling consists in combining samples from multiple individuals into a single pool that is then tested using a unique test-kit. A positive test means that at least one individual within the pool is infected. Here, we propose an…

Fast testing can help mitigate the coronavirus disease 2019 (COVID-19) pandemic. Despite their accuracy for single sample analysis, infectious diseases diagnostic tools, like RT-PCR, require substantial resources to test large populations.…

As humanity struggles to contain the global Covid-19 infection, prophylactic actions are grandly slowed down by the shortage of testing kits. Governments have taken several measures to work around this shortage: the FDA has become more…

We consider a novel method to increase the reliability of COVID-19 virus or antibody tests by using specially designed pooled testings. Instead of testing nasal swab or blood samples from individual persons, we propose to test mixtures of…

In pandemics or epidemics, public health authorities need to rapidly test a large number of individuals, both to determine the line of treatment as well as to know the spread of infection to plan containment, mitigation and future…

In the current COVID19 crisis many national healthcare systems are confronted with an acute shortage of tests for confirming SARS-CoV-2 infections. For low overall infection levels in the population, pooling of samples can drastically…

The cataclysmic contagion based calamity -- Covid-19 has shown us a clear need for a comprehensive community based strategy that overcomes the sheer complexity of controlling it and the caveats of current methods. In this regard, as seen in…

The group testing approach that achieves significant cost reduction over the individual testing approach has received a lot of interest lately for massive testing of COVID-19. Many studies simply assume samples mixed in a group are…

A key requirement in containing contagious diseases, such as the Coronavirus disease 2019 (COVID-19) pandemic, is the ability to efficiently carry out mass diagnosis over large populations. Some of the leading testing procedures, such as…

We propose a mathematical model based on probability theory to optimize COVID-19 testing by a multi-step batch testing approach with variable batch sizes. This model and simulation tool dramatically increase the efficiency and efficacy of…

We present a method for efficient estimation of the prevalence of infection in a population with high accuracy using only a small number of tests. The presented approach uses pool testing with a mix of pool sizes of various sizes. The test…

In comparison with individual testing, group testing (also known as pooled testing) is more efficient in reducing the number of tests and potentially leading to tremendous cost reduction. As indicated in the recent article posted on the US…

The usual problem for group testing is this: For a given number of individuals and a given prevalence, how many tests T* are required to find every infected individual? In real life, however, the problem is usually different: For a given…

We propose `Tapestry', a novel approach to pooled testing with application to COVID-19 testing with quantitative Reverse Transcription Polymerase Chain Reaction (RT-PCR) that can result in shorter testing time and conservation of reagents…

The corona virus disease 2019 (COVID-19) caused by the novel corona virus has an exponential rate of infection. COVID-19 is particularly notorious as the onset of symptoms in infected patients are usually delayed and there exists a large…

Suppressing SARS-CoV-2 will likely require the rapid identification and isolation of infected individuals, on an ongoing basis. RT-PCR (reverse transcription polymerase chain reaction) tests are accurate but costly, making regular testing…