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Cluster analysis faces two problems in high dimensions: first, the `curse of dimensionality' that can lead to overfitting and poor generalization performance; and second, the sheer time taken for conventional algorithms to process large…

Quantitative Methods · Quantitative Biology 2013-09-12 Shabnam N. Kadir , Dan F. M. Goodman , Kenneth D. Harris

Biclustering algorithms play a central role in the biotechnological and biomedical domains. The knowledge extracted supports the extraction of putative regulatory modules, essential to understanding diseases, aiding therapy research, and…

Databases · Computer Science 2022-12-13 Leonardo Alexandre , Rafael S. Costa , Rui Henriques

The rapid emergence of high-dimensional data in various areas has brought new challenges to current ensemble clustering research. To deal with the curse of dimensionality, recently considerable efforts in ensemble clustering have been made…

Machine Learning · Computer Science 2021-09-07 Dong Huang , Chang-Dong Wang , Jian-Huang Lai , Chee-Keong Kwoh

We study the high-dimensional linear regression problem with categorical predictors that have many levels. We propose a new estimation approach, which performs model compression via two mechanisms by simultaneously encouraging (a)…

Methodology · Statistics 2026-03-30 Kayhan Behdin , Riade Benbaki , Peter Radchenko , Rahul Mazumder

Analysis of multivariate healthcare time series data is inherently challenging: irregular sampling, noisy and missing values, and heterogeneous patient groups with different dynamics violating exchangeability. In addition, interpretability…

Machine Learning · Computer Science 2023-11-15 Onur Poyraz , Pekka Marttinen

We provide new algorithms for two tasks relating to heterogeneous tabular datasets: clustering, and synthetic data generation. Tabular datasets typically consist of heterogeneous data types (numerical, ordinal, categorical) in columns, but…

Machine Learning · Computer Science 2024-04-22 Chandrani Kumari , Rahul Siddharthan

Background and Objectives: Multidrug Resistance (MDR) is a critical global health issue, causing increased hospital stays, healthcare costs, and mortality. This study proposes an interpretable Machine Learning (ML) framework for MDR…

Clustering in high-dimensional spaces is a difficult problem which is recurrent in many domains, for example in image analysis. The difficulty is due to the fact that high-dimensional data usually live in different low-dimensional subspaces…

Statistics Theory · Mathematics 2016-08-16 Charles Bouveyron , Stéphane Girard , Cordelia Schmid

State-of-the-art clustering algorithms use heuristics to partition the feature space and provide little insight into the rationale for cluster membership, limiting their interpretability. In healthcare applications, the latter poses a…

Machine Learning · Statistics 2018-12-04 Dimitris Bertsimas , Agni Orfanoudaki , Holly Wiberg

Subtype Discovery consists in finding interpretable and consistent sub-parts of a dataset, which are also relevant to a certain supervised task. From a mathematical point of view, this can be defined as a clustering task driven by…

Machine Learning · Statistics 2021-07-06 Robin Louiset , Pietro Gori , Benoit Dufumier , Josselin Houenou , Antoine Grigis , Edouard Duchesnay

Recent advances in engineering technologies have enabled the collection of a large number of longitudinal features. This wealth of information presents unique opportunities for researchers to investigate the complex nature of diseases and…

Methodology · Statistics 2023-11-27 Zihang Lu , Noirrit Kiran Chandra

In many applications, data can be heterogeneous in the sense of spanning latent groups with different underlying distributions. When predictive models are applied to such data the heterogeneity can affect both predictive performance and…

Machine Learning · Statistics 2022-05-04 Thomas Lartigue , Sach Mukherjee

Co-clustering simultaneously clusters rows and columns, revealing more fine-grained groups. However, existing co-clustering methods suffer from poor scalability and cannot handle large-scale data. This paper presents a novel and scalable…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-20 Zihan Wu , Zhaoke Huang , Hong Yan

Subspace clustering is an important unsupervised clustering approach. It is based on the assumption that the high-dimensional data points are approximately distributed around several low-dimensional linear subspaces. The majority of the…

Machine Learning · Computer Science 2021-12-20 Maryam Abdolali , Nicolas Gillis

We introduce a mixture model for censored durations (C-mix), and develop maximum likelihood inference for the joint estimation of the time distributions and latent regression parameters of the model. We consider a high-dimensional setting,…

Machine Learning · Statistics 2017-11-28 Simon Bussy , Agathe Guilloux , Stéphane Gaïffas , Anne-Sophie Jannot

Mixture models are a standard approach to dealing with heterogeneous data with non-i.i.d. structure. However, when the dimension $p$ is large relative to sample size $n$ and where either or both of means and covariances/graphical models may…

Machine Learning · Statistics 2019-02-25 Bernd Taschler , Frank Dondelinger , Sach Mukherjee

The problem of complex data analysis is a central topic of modern statistical science and learning systems and is becoming of broader interest with the increasing prevalence of high-dimensional data. The challenge is to develop statistical…

Machine Learning · Statistics 2018-03-05 Faicel Chamroukhi , Hien D. Nguyen

We consider the problem of simultaneously clustering and learning a linear representation of data lying close to a union of low-dimensional manifolds, a fundamental task in machine learning and computer vision. When the manifolds are…

Machine Learning · Computer Science 2023-08-25 Tianjiao Ding , Shengbang Tong , Kwan Ho Ryan Chan , Xili Dai , Yi Ma , Benjamin D. Haeffele

A probabilistic clustering algorithm is proposed for the analysis of forensic DNA mixtures in which individual cells are isolated and short tandem repeats are amplified using the polymerase chain reaction to generate single cell…

Applications · Statistics 2025-10-14 Robert G. Cowell

Covariance matrices provide a valuable source of information about complex interactions and dependencies within the data. However, from a clustering perspective, this information has often been underutilized and overlooked. Indeed, commonly…

Methodology · Statistics 2024-09-02 Andrea Cappozzo , Alessandro Casa