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A model based on a thermodynamic approach is proposed for predicting the dynamics of communicable epidemics in a city, when the epidemic is governed by controlling efforts of multiple scales so that an entropy is associated with the system.…

Medical Physics · Physics 2013-10-01 W. B. Wang , Z. N. Wu , Z. M. Cao , R. F. Hu

Estimating parameters of a diffusion process given continuous-time observations of the process via maximum likelihood approaches or, online, via stochastic gradient descent or Kalman filter formulations constitutes a well-established…

Methodology · Statistics 2025-03-17 Jan Albrecht , Sebastian Reich

We develop a multiple compartment Susceptible-Infected-Recovered (SIR) model to analyze the spread of several infectious diseases through different geographic areas. Additionally, we propose a data-quality sensitive optimization framework…

Populations and Evolution · Quantitative Biology 2019-06-21 Inbar Seroussi , Nir Levy , Daniela Paolotti , Nir Sochen , Elad Yom-Tov

In this paper, we address a social planner's optimal control problem for a partially observable stochastic epidemic model. The control measures include social distancing, testing, and vaccination. Using a diffusion approximation for the…

Optimization and Control · Mathematics 2025-03-11 Ibrahim Mbouandi Njiasse , Florent Ouabo Kamkumo , Ralf Wunderlich

For many infectious disease outbreaks, the at-risk population changes their behavior in response to the outbreak severity, causing the transmission dynamics to change in real-time. Behavioral change is often ignored in epidemic modeling…

Methodology · Statistics 2023-10-25 Caitlin Ward , Rob Deardon , Alexandra M. Schmidt

We develop a stochastic epidemic model progressing over dynamic networks, where infection rates are heterogeneous and may vary with individual-level covariates. The joint dynamics are modeled as a continuous-time Markov chain such that…

Methodology · Statistics 2021-12-16 Fan Bu , Allison E. Aiello , Alexander Volfovsky , Jason Xu

We consider a continuous-time Markov chain model of SIR disease dynamics with two levels of mixing. For this so-called stochastic households model, we provide two methods for inferring the model parameters---governing within-household…

Populations and Evolution · Quantitative Biology 2018-02-07 James N. Walker , Joshua V. Ross , Andrew J. Black

Many disease models focus on characterizing the underlying transmission mechanism but make simple, possibly naive assumptions about how infections are reported. In this note, we use a simple deterministic Susceptible-Infected-Removed (SIR)…

Populations and Evolution · Quantitative Biology 2019-11-28 Sang Woo Park , Benjamin M. Bolker

Multitype branching processes with immigration in one type are used to model the dynamics of stage-structured plant populations. Parametric inference is first carried out when count data of all types are observed. Statistical…

Applications · Statistics 2009-02-27 Catherine Laredo , Olivier David , Aurélie Garnier

Infectious disease outbreaks have precipitated a profusion of mathematical models. Epidemic curves predicted by these models are typically qualitatively similar, despite distinct model assumptions, but there is no theoretical explanation…

Populations and Evolution · Quantitative Biology 2026-02-23 David J. D. Earn , Todd L. Parsons

This paper presents a state estimation-based robust optimal control strategy for influenza epidemics in an interactive human society in the presence of modeling uncertainties. Interactive society is influenced by the random entrance of…

Systems and Control · Electrical Eng. & Systems 2020-11-12 Vahid Azimi , Mojtaba Sharifi , Seyed Fakoorian , Thang Tien Nguyen , Van Van Huynh

Compartmental models, especially the Susceptible-Infected-Removed (SIR) model, have long been used to understand the behaviour of various diseases. Allowing parameters, such as the transmission rate, to be time-dependent functions makes it…

Methodology · Statistics 2024-09-27 Son Luu , Edward Susko , Lam Si Tung Ho

We propose a framework for Bayesian non-parametric estimation of the rate at which new infections occur assuming that the epidemic is partially observed. The developed methodology relies on modelling the rate at which new infections occur…

Methodology · Statistics 2014-12-16 Edward S. Knock , Theodore Kypraios

Recent work has focused attention on statistical inference for the population distribution of the number of sexual partners based on survey data. The characteristics of these distributions are of interest as components of mathematical…

Disordered Systems and Neural Networks · Physics 2007-05-23 Mark S. Handcock , James Holland Jones , Martina Morris

Infectious diseases on farms pose both public and animal health risks, so understanding how they spread between farms is crucial for developing disease control strategies to prevent future outbreaks. We develop novel Bayesian nonparametric…

Applications · Statistics 2021-08-24 R. G. Seymour , T. Kypraios , P. D. O'Neill , T. J. Hagenaars

Compartmental models provide simple and efficient tools to analyze the relevant transmission processes during an outbreak, to produce short-term forecasts or transmission scenarios, and to assess the impact of vaccination campaigns.…

Numerical Analysis · Mathematics 2025-02-19 Caterina Millevoi , Damiano Pasetto , Massimiliano Ferronato

We consider the estimation of average treatment effects in observational studies and propose a new framework of robust causal inference with unobserved confounders. Our approach is based on distributionally robust optimization and proceeds…

Methodology · Statistics 2023-02-06 Dimitris Bertsimas , Kosuke Imai , Michael Lingzhi Li

Using the continuous-time susceptible-infected-susceptible (SIS) model on networks, we investigate the problem of inferring the class of the underlying network when epidemic data is only available at population-level (i.e. the number of…

Populations and Evolution · Quantitative Biology 2019-12-05 F. Di Lauro , J. -C. Croix , M. Dashti , L. Berthouze , I. Z. Kiss

We present a scalable and robust Bayesian inference method for linear state space models. The method is applied to demand forecasting in the context of a large e-commerce platform, paying special attention to intermittent and bursty target…

Infectious diseases pose significant human and economic burdens. Accurately forecasting disease incidence can enable public health agencies to respond effectively to existing or emerging diseases. Despite progress in the field, developing…

Machine Learning · Computer Science 2024-09-04 Michael Morris