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We developed a voice-driven artificial intelligence (AI) system that guides anyone - from paramedics to family members - through expert-level stroke evaluations using natural conversation, while also enabling smartphone video capture of key…

While ischemic stroke is a leading cause of death worldwide, there has been little success translating putative cerebroprotectants from rodent preclinical trials to human patients. We investigated computational image-based assessment tools…

Background: Stroke is second-leading cause of disability and death among adults. Approximately 17 million people suffer from a stroke annually, with about 85% being ischemic strokes. Predicting mortality of ischemic stroke patients in…

Machine Learning · Computer Science 2024-09-04 Armin Abdollahi , Negin Ashrafi , Maryam Pishgar

Currently, strokes are the leading cause of adult disability in the United States. Traditional treatment and rehabilitation options such as physical therapy and tissue plasminogen activator are limited in their effectiveness and ability to…

Signal Processing · Electrical Eng. & Systems 2020-08-20 Mohammad-Parsa Hosseini , Cecilia Hemingway , Jerard Madamba , Alexander McKee , Natalie Ploof , Jennifer Schuman , Elliot Voss

This paper addresses the question of the brain's critical dynamics after an injury such as a stroke. It is hypothesized that the healthy brain operates near a phase transition (critical point), which provides optimal conditions for…

Neurons and Cognition · Quantitative Biology 2023-08-01 Jakub Janarek , Zbigniew Drogosz , Jacek Grela , Jeremi K. Ochab , Paweł Oświęcimka

This paper proposes a novel, simple and minimally invasive method for stroke volume variation assessment using arterial blood pressure measurements. The arterial blood pressure signal is reconstructed using a semi-classical signal analysis…

Objective: Acute intracranial hypertension is an important risk factor of secondary brain damage after traumatic brain injury. Hypertensive episodes are often diagnosed reactively, leading to late detection and lost time for intervention…

Signal Processing · Electrical Eng. & Systems 2020-12-03 Matthias Hüser , Adrian Kündig , Walter Karlen , Valeria De Luca , Martin Jaggi

Stroke is the second leading cause of mortality worldwide. Immediate attention and diagnosis play a crucial role regarding patient prognosis. The key to diagnosis consists in localizing and delineating brain lesions. Standard stroke…

Image and Video Processing · Electrical Eng. & Systems 2024-09-05 Santiago Gómez , Daniel Mantilla , Gustavo Garzón , Edgar Rangel , Andrés Ortiz , Franklin Sierra-Jerez , Fabio Martínez

The trajectory of an individual's recovery after traumatic brain injury (TBI) is heterogeneous, with complete recovery in some cases but persistent disability in others. We hypothesized that changes in structural brain network abnormalities…

Stroke poses a significant global health threat, with millions affected annually, leading to substantial morbidity and mortality. Current stroke risk assessment for the general population relies on markers such as demographics, blood tests,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-24 Yu Xi Huang , Simon Mahler , Aidin Abedi , Julian Michael Tyszka , Yu Tung Lo , Patrick D. Lyden , Jonathan Russin , Charles Liu , Changhuei Yang

Predicting the final ischaemic stroke lesion provides crucial information regarding the volume of salvageable hypoperfused tissue, which helps physicians in the difficult decision-making process of treatment planning and intervention.…

Image and Video Processing · Electrical Eng. & Systems 2021-01-05 Adriano Pinto , Sérgio Pereira , Raphael Meier , Roland Wiest , Victor Alves , Mauricio Reyes , Carlos A. Silva

Distinguishing acute ischemic strokes (AIS) from stroke mimics (SMs), particularly in cases involving medium and small vessel occlusions, remains a significant diagnostic challenge. While computed tomography (CT) based protocols are…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Marijn Borghouts , Richard McKinley , Manuel Köstner , Josien Pluim , Roland Wiest , Ruisheng Su

Postoperative stroke remains a critical complication in elderly surgical intensive care unit (SICU) patients, contributing to prolonged hospitalization, elevated healthcare costs, and increased mortality. Accurate early risk stratification…

Quantitative Methods · Quantitative Biology 2025-06-05 Tinghuan Li , Shuheng Chen , Junyi Fan , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Background and Purpose: We aimed to develop and evaluate an automatic acute ischemic stroke-related (AIS) detection system involving a two-stage deep learning model. Methods: We included 238 cases from two different institutions.…

Image and Video Processing · Electrical Eng. & Systems 2020-09-09 Mizuho Nishio , Sho Koyasu , Shunjiro Noguchi , Takao Kiguchi , Kanako Nakatsu , Thai Akasaka , Hiroki Yamada , Kyo Itoh

Aphasia, a language disorder primarily caused by a stroke, is traditionally diagnosed using behavioral language tests. However, these tests are time-consuming, require manual interpretation by trained clinicians, suffer from low ecological…

Signal Processing · Electrical Eng. & Systems 2024-01-22 Pieter De Clercq , Corentin Puffay , Jill Kries , Hugo Van Hamme , Maaike Vandermosten , Tom Francart , Jonas Vanthornhout

For acute ischemic stroke (AIS) patients with large vessel occlusions, clinicians must decide if the benefit of mechanical thrombectomy (MTB) outweighs the risks and potential complications following an invasive procedure. Pre-treatment…

Image and Video Processing · Electrical Eng. & Systems 2024-04-19 Haoyue Zhang , Jennifer S. Polson , Eric J. Yang , Kambiz Nael , William Speier , Corey W. Arnold

Stroke is one of the leading causes of disability worldwide. The efficacy of recovery is determined by a variety of factors, including patient adherence to rehabilitation programs. One way to increase patient adherence to their…

Human-Computer Interaction · Computer Science 2024-02-20 Alicia Ouskine , Adrian D. C. Chan , Fateme Rajabiyazdi

Accelerometry has been extensively studied as an objective means of measuring upper limb function in patients post-stroke. The objective of this paper is to determine whether the accelerometry-derived measurements frequently used in more…

Machine Learning · Computer Science 2023-11-09 Mackenzie Wallich , Kenneth Lai , Svetlana Yanushkevich

Neuroinflammation immediately follows the onset of ischemic stroke in the middle cerebral artery. During this process, microglial cells are activated in and recruited to the penumbra. Microglial cells can be activated into two different…

Cell Behavior · Quantitative Biology 2025-08-19 Sara Amato , Andrea Arnold

This study assessed the safety, feasibility, and acceptability of a novel device to monitor ischaemic stroke patients. The device captured electroencephalography (EEG) and electrocardiography (ECG) data to compute an ECG-based metric termed…