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We propose a variational autoencoder (VAE) approach for parameter estimation in nonlinear mixed-effects models based on ordinary differential equations (NLME-ODEs) using longitudinal data from multiple subjects. In moderate dimensions,…

Methodology · Statistics 2026-02-11 Zhe Li , Mélanie Prague , Rodolphe Thiébaut , Quentin Clairon

We investigate the detection of weak complex-valued signals immersed in non-Gaussian, range-varying interference, with emphasis on maritime radar scenarios. The proposed methodology exploits a Complex-valued Variational AutoEncoder (CVAE)…

As one of the most popular generative models, Variational Autoencoder (VAE) approximates the posterior of latent variables based on amortized variational inference. However, when the decoder network is sufficiently expressive, VAE may lead…

Machine Learning · Computer Science 2021-10-26 Dazhong Shen , Chuan Qin , Chao Wang , Hengshu Zhu , Enhong Chen , Hui Xiong

Building a scalable machine learning system for unsupervised anomaly detection via representation learning is highly desirable. One of the prevalent methods is using a reconstruction error from variational autoencoder (VAE) via maximizing…

Machine Learning · Computer Science 2020-05-08 Seonho Park , George Adosoglou , Panos M. Pardalos

We consider the problem of detecting out-of-distribution (OOD) samples in deep reinforcement learning. In a value based reinforcement learning setting, we propose to use uncertainty estimation techniques directly on the agent's value…

Machine Learning · Computer Science 2019-01-09 Andreas Sedlmeier , Thomas Gabor , Thomy Phan , Lenz Belzner , Claudia Linnhoff-Popien

Detecting out-of-distribution (OOD) samples in medical imaging plays an important role for downstream medical diagnosis. However, existing OOD detectors are demonstrated on natural images composed of inter-classes and have difficulty…

Image and Video Processing · Electrical Eng. & Systems 2022-01-28 Xiaoyuan Guo , Judy Wawira Gichoya , Saptarshi Purkayastha , Imon Banerjee

Deep generative models have been demonstrated as state-of-the-art density estimators. Yet, recent work has found that they often assign a higher likelihood to data from outside the training distribution. This seemingly paradoxical behavior…

Machine Learning · Computer Science 2022-01-19 Jakob D. Havtorn , Jes Frellsen , Søren Hauberg , Lars Maaløe

Out-of-distribution (OOD) detection, i.e., finding test samples derived from a different distribution than the training set, as well as reasoning about such samples (OOD reasoning), are necessary to ensure the safety of results generated by…

Machine Learning · Computer Science 2022-10-19 Zahra Rahiminasab , Michael Yuhas , Arvind Easwaran

The superior performance of object detectors is often established under the condition that the test samples are in the same distribution as the training data. However, in many practical applications, out-of-distribution (OOD) instances are…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Tianhao Zhang , Shenglin Wang , Nidhal Bouaynaya , Radu Calinescu , Lyudmila Mihaylova

Learning Enabled Components (LECs) are widely being used in a variety of perception based autonomy tasks like image segmentation, object detection, end-to-end driving, etc. These components are trained with large image datasets with…

Computer Vision and Pattern Recognition · Computer Science 2020-03-20 Vijaya Kumar Sundar , Shreyas Ramakrishna , Zahra Rahiminasab , Arvind Easwaran , Abhishek Dubey

The ability to detect Out-of-Distribution (OOD) data is important in safety-critical applications of deep learning. The aim is to separate In-Distribution (ID) data drawn from the training distribution from OOD data using a measure of…

Machine Learning · Computer Science 2022-09-21 Guoxuan Xia , Christos-Savvas Bouganis

Variational autoencoders (VAE) are a powerful and widely-used class of models to learn complex data distributions in an unsupervised fashion. One important limitation of VAEs is the prior assumption that latent sample representations are…

Machine Learning · Computer Science 2018-11-27 Francesco Paolo Casale , Adrian V Dalca , Luca Saglietti , Jennifer Listgarten , Nicolo Fusi

Estimation of uncertainty in deep learning models is of vital importance, especially in medical imaging, where reliance on inference without taking into account uncertainty could lead to misdiagnosis. Recently, the probabilistic Variational…

Machine Learning · Computer Science 2020-10-20 Haleh Akrami , Anand A. Joshi , Sergul Aydore , Richard M. Leahy

Variational Auto-Encoders (VAEs) are capable of learning latent representations for high dimensional data. However, due to the i.i.d. assumption, VAEs only optimize the singleton variational distributions and fail to account for the…

Machine Learning · Computer Science 2020-04-20 Da Tang , Dawen Liang , Tony Jebara , Nicholas Ruozzi

Out-of-distribution (OOD) detection is important for deploying reliable machine learning models on real-world applications. Recent advances in outlier exposure have shown promising results on OOD detection via fine-tuning model with…

Machine Learning · Computer Science 2023-10-27 Jianing Zhu , Geng Yu , Jiangchao Yao , Tongliang Liu , Gang Niu , Masashi Sugiyama , Bo Han

Out-of-distribution (OOD) detection and uncertainty estimation (UE) are critical components for building safe machine learning systems, especially in real-world scenarios where unexpected inputs are inevitable. However the two problems…

Machine Learning · Computer Science 2025-12-01 Pirzada Suhail , Rehna Afroz , Gouranga Bala , Amit Sethi

Out-of-distribution (OOD) detection holds significant importance across many applications. While semantic and domain-shift OOD problems are well-studied, this work focuses on covariate shifts - subtle variations in the data distribution…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Francisco Caetano , Christiaan Viviers , Luis A. Zavala-Mondragón , Peter H. N. de With , Fons van der Sommen

We propose a novel Conditional Latent space Variational Autoencoder (CL-VAE) to perform improved pre-processing for anomaly detection on data with known inlier classes and unknown outlier classes. This proposed variational autoencoder (VAE)…

Machine Learning · Computer Science 2024-10-17 Oskar Åström , Alexandros Sopasakis

Structural Health Monitoring of Floating Offshore Wind Turbines (FOWTs) is critical for ensuring operational safety and efficiency. However, identifying damage in components like mooring systems from limited sensor data poses a challenging…

Computational Engineering, Finance, and Science · Computer Science 2026-01-13 Ana Fernandez-Navamuel , Martin Alberto Diaz Viera , Matteo Croci

When deploying a trained machine learning model in the real world, it is inevitable to receive inputs from out-of-distribution (OOD) sources. For instance, in continual learning settings, it is common to encounter OOD samples due to the…

Machine Learning · Computer Science 2024-01-23 Chuanwen Feng , Wenlong Chen , Ao Ke , Yilong Ren , Xike Xie , S. Kevin Zhou